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Loss of Chromosome 10

MedGen UID:
273492
•Concept ID:
C1517947
•
Cell or Molecular Dysfunction
Synonym: del(10)

Definition

A cytogenetic abnormality that refers to loss of all or part of chromosome 10. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLoss of Chromosome 10

Professional guidelines

PubMed

Neuro-oncology Treatment Strategies for Primary Glial Tumors.
Santos-Pinheiro F, Graber JJ
Semin Neurol 2023 Dec;43(6):889-896. Epub 2023 Dec 14 doi: 10.1055/s-0043-1776764. PMID: 38096849
The role of neuropathology in the management of newly diagnosed glioblastoma: a systematic review and evidence-based clinical practice guideline.
Velázquez Vega JE, Brat DJ, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):143-164. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03616-3. PMID: 33215342
Survival of diffuse astrocytic glioma, IDH1/2 wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.
Tesileanu CMS, Dirven L, Wijnenga MMJ, Koekkoek JAF, Vincent AJPE, Dubbink HJ, Atmodimedjo PN, Kros JM, van Duinen SG, Smits M, Taphoorn MJB, French PJ, van den Bent MJ
Neuro Oncol 2020 Apr 15;22(4):515-523. doi: 10.1093/neuonc/noz200. PMID: 31637414Free PMC Article

Recent clinical studies

Diagnosis

Clinical, histopathological, and molecular features of IDH-wildtype indolent diffuse glioma: comparison with typical glioblastoma.
Suzuki H, Ono T, Koyota S, Takahashi M, Sugai T, Nanjo H, Shimizu H
J Neurooncol 2022 Sep;159(2):397-408. Epub 2022 Jul 2 doi: 10.1007/s11060-022-04074-9. PMID: 35779193

Prognosis

Clinical, histopathological, and molecular features of IDH-wildtype indolent diffuse glioma: comparison with typical glioblastoma.
Suzuki H, Ono T, Koyota S, Takahashi M, Sugai T, Nanjo H, Shimizu H
J Neurooncol 2022 Sep;159(2):397-408. Epub 2022 Jul 2 doi: 10.1007/s11060-022-04074-9. PMID: 35779193

Supplemental Content

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    Practice guidelines

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