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Uterine corpus epithelioid leiomyosarcoma

MedGen UID:
274363
Concept ID:
C1519851
Neoplastic Process
Synonyms: body of uterus epithelioid leiomyosarcoma; epithelioid leiomyosarcoma of body of uterus; Uterine Corpus Epithelioid Leiomyosarcoma; uterine corpus epithelioid leiomyosarcoma; uterine epithelioid leiomyosarcoma
 
Monarch Initiative: MONDO:0003782

Definition

A morphologic variant of leiomyosarcoma arising from the uterine corpus. It is characterized by the presence of epithelioid round cells with eosinophilic to clear cytoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine corpus epithelioid leiomyosarcoma

Professional guidelines

PubMed

Obstet Gynecol 2021 Mar 1;137(3):e63-e74. doi: 10.1097/AOG.0000000000004291. PMID: 33595252
Obstet Gynecol 2019 Mar;133(3):e238-e248. doi: 10.1097/AOG.0000000000003126. PMID: 30801477
Vongtama V, Karlen JR, Piver SM, Tsukada Y, Moore RH
AJR Am J Roentgenol 1976 Jan;126(1):139-47. doi: 10.2214/ajr.126.1.139. PMID: 175673

Recent clinical studies

Etiology

Asano H, Oda K, Yoshihara K, Ito YM, Matsumura N, Shimada M, Watari H, Enomoto T
J Gynecol Oncol 2022 Jul;33(4):e55. Epub 2022 May 3 doi: 10.3802/jgo.2022.33.e55. PMID: 35557035Free PMC Article
Hanley KZ, Birdsong GG, Mosunjac MB
Arch Pathol Lab Med 2017 Apr;141(4):528-541. Epub 2017 Feb 28 doi: 10.5858/arpa.2016-0284-SA. PMID: 28353387
Suh DH, Kim M, Kim HJ, Lee KH, Kim JW
J Gynecol Oncol 2016 Nov;27(6):e53. doi: 10.3802/jgo.2016.27.e53. PMID: 27775259Free PMC Article
Suh DH, Lee KH, Kim K, Kang S, Kim JW
J Gynecol Oncol 2015 Apr;26(2):156-67. doi: 10.3802/jgo.2015.26.2.156. PMID: 25872896Free PMC Article
Fadare O
Adv Anat Pathol 2011 Jan;18(1):60-74. doi: 10.1097/PAP.0b013e3182026be7. PMID: 21169739

Diagnosis

Yuk JS, Kim M
J Obstet Gynaecol 2022 Oct;42(7):3067-3072. Epub 2022 Jul 1 doi: 10.1080/01443615.2022.2091925. PMID: 35775461
Hanley KZ, Birdsong GG, Mosunjac MB
Arch Pathol Lab Med 2017 Apr;141(4):528-541. Epub 2017 Feb 28 doi: 10.5858/arpa.2016-0284-SA. PMID: 28353387
Suh DH, Lee KH, Kim K, Kang S, Kim JW
J Gynecol Oncol 2015 Apr;26(2):156-67. doi: 10.3802/jgo.2015.26.2.156. PMID: 25872896Free PMC Article
Gockley AA, Rauh-Hain JA, del Carmen MG
Int J Gynecol Cancer 2014 Nov;24(9):1538-42. doi: 10.1097/IGC.0000000000000290. PMID: 25304676
Fadare O
Adv Anat Pathol 2011 Jan;18(1):60-74. doi: 10.1097/PAP.0b013e3182026be7. PMID: 21169739

Therapy

Yuk JS, Kim M
J Obstet Gynaecol 2022 Oct;42(7):3067-3072. Epub 2022 Jul 1 doi: 10.1080/01443615.2022.2091925. PMID: 35775461
Asano H, Oda K, Yoshihara K, Ito YM, Matsumura N, Shimada M, Watari H, Enomoto T
J Gynecol Oncol 2022 Jul;33(4):e55. Epub 2022 May 3 doi: 10.3802/jgo.2022.33.e55. PMID: 35557035Free PMC Article
Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, Nagase Y, Matsuzaki S, Nakagawa S, Hiramatsu K, Okazawa A, Kimura T, Egawa-Takata T, Kobayashi E, Ueda Y, Yoshino K, Naka T, Kimura T
Am J Obstet Gynecol 2021 Feb;224(2):197.e1-197.e23. Epub 2020 Aug 19 doi: 10.1016/j.ajog.2020.08.028. PMID: 32822640
Suh DH, Kim M, Kim HJ, Lee KH, Kim JW
J Gynecol Oncol 2016 Nov;27(6):e53. doi: 10.3802/jgo.2016.27.e53. PMID: 27775259Free PMC Article
Suh DH, Lee KH, Kim K, Kang S, Kim JW
J Gynecol Oncol 2015 Apr;26(2):156-67. doi: 10.3802/jgo.2015.26.2.156. PMID: 25872896Free PMC Article

Prognosis

Hanley KZ, Birdsong GG, Mosunjac MB
Arch Pathol Lab Med 2017 Apr;141(4):528-541. Epub 2017 Feb 28 doi: 10.5858/arpa.2016-0284-SA. PMID: 28353387
Suh DH, Lee KH, Kim K, Kang S, Kim JW
J Gynecol Oncol 2015 Apr;26(2):156-67. doi: 10.3802/jgo.2015.26.2.156. PMID: 25872896Free PMC Article
Gockley AA, Rauh-Hain JA, del Carmen MG
Int J Gynecol Cancer 2014 Nov;24(9):1538-42. doi: 10.1097/IGC.0000000000000290. PMID: 25304676
Fadare O
Adv Anat Pathol 2011 Jan;18(1):60-74. doi: 10.1097/PAP.0b013e3182026be7. PMID: 21169739
DiSaia PJ, Pecorelli S
Semin Surg Oncol 1994 Sep-Oct;10(5):369-73. doi: 10.1002/ssu.2980100510. PMID: 7997731

Clinical prediction guides

Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, Nagase Y, Matsuzaki S, Nakagawa S, Hiramatsu K, Okazawa A, Kimura T, Egawa-Takata T, Kobayashi E, Ueda Y, Yoshino K, Naka T, Kimura T
Am J Obstet Gynecol 2021 Feb;224(2):197.e1-197.e23. Epub 2020 Aug 19 doi: 10.1016/j.ajog.2020.08.028. PMID: 32822640
Desai VB, Wright JD, Gross CP, Lin H, Boscoe FP, Hutchison LM, Schwartz PE, Xu X
Am J Obstet Gynecol 2019 Jul;221(1):39.e1-39.e14. Epub 2019 Mar 7 doi: 10.1016/j.ajog.2019.02.051. PMID: 30853364Free PMC Article
Suh DH, Kim M, Kim HJ, Lee KH, Kim JW
J Gynecol Oncol 2016 Nov;27(6):e53. doi: 10.3802/jgo.2016.27.e53. PMID: 27775259Free PMC Article
Suh DH, Lee KH, Kim K, Kang S, Kim JW
J Gynecol Oncol 2015 Apr;26(2):156-67. doi: 10.3802/jgo.2015.26.2.156. PMID: 25872896Free PMC Article
Fadare O
Adv Anat Pathol 2011 Jan;18(1):60-74. doi: 10.1097/PAP.0b013e3182026be7. PMID: 21169739

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