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Cervical adenoid basal carcinoma

MedGen UID:
275704
•Concept ID:
C1516403
•
Neoplastic Process
Synonyms: Adenoid basal carcinoma of cervix uteri; cervical adenoid basal cancer; Cervical Adenoid Basal Carcinoma; cervical adenoid basal carcinoma
SNOMED CT: Adenoid basal carcinoma of cervix uteri (763063001); Cervical adenoid basal carcinoma (763063001)
 
Monarch Initiative: MONDO:0006132

Definition

A rare low grade carcinoma that arises from the cervix. It is characterized by the presence of nests of basaloid cells with focal glandular formations. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical adenoid basal carcinoma

Professional guidelines

PubMed

Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.
Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926
Endocervical adenocarcinoma and its variants: their morphology and differential diagnosis.
Young RH, Clement PB
Histopathology 2002 Sep;41(3):185-207. doi: 10.1046/j.1365-2559.2002.01462.x. PMID: 12207781
A reappraisal of "basaloid carcinoma" of the cervix, and the differential diagnosis of basaloid cervical neoplasms.
Grayson W, Cooper K
Adv Anat Pathol 2002 Sep;9(5):290-300. doi: 10.1097/00125480-200209000-00003. PMID: 12195218

Recent clinical studies

Etiology

Top 10 Basaloid Neoplasms of the Sinonasal Tract.
Baněčková M, Cox D
Head Neck Pathol 2023 Mar;17(1):16-32. Epub 2023 Mar 16 doi: 10.1007/s12105-022-01508-8. PMID: 36928732Free PMC Article
Retrospective Study of Buccal Mucosal Salivary Neoplasms.
Alramadhan SA, Fitzpatrick SG, Cohen DM, Bhattacharyya I, Islam MN
Head Neck Pathol 2020 Dec;14(4):1013-1020. Epub 2020 Jun 6 doi: 10.1007/s12105-020-01190-8. PMID: 32506376Free PMC Article
Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016
Malignant mullerian mixed tumors of the uterine cervix: a report of nine cases of a neoplasm with morphology often different from its counterpart in the corpus.
Clement PB, Zubovits JT, Young RH, Scully RE
Int J Gynecol Pathol 1998 Jul;17(3):211-22. PMID: 9656116
Histopathology of malignant salivary gland tumours.
Seifert G
Eur J Cancer B Oral Oncol 1992 Jul;28B(1):49-56. doi: 10.1016/0964-1955(92)90013-q. PMID: 1330147

Diagnosis

Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.
Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926
More than meets the eye.
White-Gibson A, Lennon P, O'Regan E, Timon C
BMJ Case Rep 2019 Feb 7;12(2) doi: 10.1136/bcr-2015-212000. PMID: 30737321Free PMC Article
Cervical Adenoid Basal Carcinoma: Clinicopathologic Features of 9 Cases With Reference to CK17 and Ki-67 Expression.
Liang Y, Lü B, Zhou C
J Low Genit Tract Dis 2019 Jan;23(1):77-81. doi: 10.1097/LGT.0000000000000428. PMID: 30106815
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839
Endocervical adenocarcinoma and its variants: their morphology and differential diagnosis.
Young RH, Clement PB
Histopathology 2002 Sep;41(3):185-207. doi: 10.1046/j.1365-2559.2002.01462.x. PMID: 12207781

Therapy

Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016
Outcomes of dacryocystorhinostomy in patients with head and neck cancer treated with high-dose radiation therapy.
El-Sawy T, Ali R, Nasser QJ, Esmaeli B
Ophthalmic Plast Reconstr Surg 2012 May-Jun;28(3):196-8. doi: 10.1097/IOP.0b013e31824c11df. PMID: 22460683Free PMC Article
Cervical adenoid basal carcinoma associated with invasive squamous cell carcinoma: a report of rare co-existence and review of literature.
Viriyapak B, Park ST, Lee AW, Park JS, Lee CW, Song MJ, Hur SY
World J Surg Oncol 2011 Oct 18;9:132. doi: 10.1186/1477-7819-9-132. PMID: 22004883Free PMC Article
Persistent and/or late complications of combined radiation therapy and hyperthermia.
Ben-Yosef R, Kapp DS
Int J Hyperthermia 1992 Nov-Dec;8(6):733-45. doi: 10.3109/02656739209005021. PMID: 1479199
Radiation-induced skin cancer of the head and neck.
Martin H, Strong E, Spiro RH
Cancer 1970 Jan;25(1):61-71. doi: 10.1002/1097-0142(197001)25:1<61::aid-cncr2820250110>3.0.co;2-w. PMID: 4312028

Prognosis

Retrospective Study of Buccal Mucosal Salivary Neoplasms.
Alramadhan SA, Fitzpatrick SG, Cohen DM, Bhattacharyya I, Islam MN
Head Neck Pathol 2020 Dec;14(4):1013-1020. Epub 2020 Jun 6 doi: 10.1007/s12105-020-01190-8. PMID: 32506376Free PMC Article
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839
Adenoid basal carcinoma of the uterine cervix: immunohistochemical study and literature review.
Senzaki H, Osaki T, Uemura Y, Kiyozuka Y, Ogura E, Okamura A, Tsubura A
Jpn J Clin Oncol 1997 Dec;27(6):437-41. doi: 10.1093/jjco/27.6.437. PMID: 9438010
Basaloid squamous cell carcinoma of the head and neck: clinicopathological features and differential diagnosis.
Barnes L, Ferlito A, Altavilla G, MacMillan C, Rinaldo A, Doglioni C
Ann Otol Rhinol Laryngol 1996 Jan;105(1):75-82. doi: 10.1177/000348949610500115. PMID: 8546432
Histopathology of malignant salivary gland tumours.
Seifert G
Eur J Cancer B Oral Oncol 1992 Jul;28B(1):49-56. doi: 10.1016/0964-1955(92)90013-q. PMID: 1330147

Clinical prediction guides

Identification and characterization of primary cilia-positive salivary gland tumours exhibiting basaloid/myoepithelial differentiation.
Shinmura K, Kusafuka K, Kawasaki H, Kato H, Hariyama T, Tsuchiya K, Kawanishi Y, Funai K, Misawa K, Mineta H, Sugimura H
J Pathol 2021 Aug;254(5):519-530. Epub 2021 May 29 doi: 10.1002/path.5688. PMID: 33931860
Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.
Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926
Basal Cell Carcinoma. Analysis of 395 cases localized in the neck, ear and nose region.
Kornevs E, Apse IA, Safronovs TJ, Krastina A, Paparde A, Lauskis G, Salms G
Stomatologija 2020;22(1):9-16. PMID: 32706341
Adenoid basal carcinoma arising in the cervical polyp: an immunohistochemical study of stromal cells.
Kuroda N, Hirano K, Ohara M, Hirouchi T, Mizuno K, Kubo A, Enzan H
Med Mol Morphol 2007 Jun;40(2):112-4. Epub 2007 Jun 18 doi: 10.1007/s00795-006-0343-6. PMID: 17572848
Giant basal cell carcinoma.
Curry MC, Montgomery H, Winkelmann RK
Arch Dermatol 1977 Mar;113(3):316-9. PMID: 843097

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