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Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements

MedGen UID:
307990
•Concept ID:
C1514226
•
Neoplastic Process

Definition

An ovarian poorly differentiated Sertoli-Leydig cell tumor. It is characterized by the presence of a heterologous component, usually consisting of cartilage, skeletal muscle, or rhabdomyosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPoorly Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements

Recent clinical studies

Etiology

Outcomes in ovarian Sertoli-Leydig cell tumor: A report from the International Pleuropulmonary Blastoma/DICER1 and Ovarian and Testicular Stromal Tumor Registries.
Nelson AT, Harris AK, Watson D, Kamihara J, Chen KS, Stall JN, Devins KM, Young RH, Olson DR, Mallinger PHR, Mitchell SG, Hoffman LM, Halliday G, Suleymanova AM, Glade Bender JL, Messinger YH, Herzog CE, Field AL, Frazier AL, Stewart DR, Dehner LP, Hill DA, Billmire DF, Schneider DT, Schultz KAP
Gynecol Oncol 2024 Jul;186:117-125. Epub 2024 Apr 23 doi: 10.1016/j.ygyno.2024.04.005. PMID: 38657450Free PMC Article
Sertoli-Leydig cell tumor of ovary in children: A report of two cases, including retiform variant.
Sarkar P, Sengupta M, Chatterjee U, Ghosh D
Indian J Pathol Microbiol 2021 Jul-Sep;64(3):559-562. doi: 10.4103/IJPM.IJPM_443_20. PMID: 34341273

Diagnosis

Outcomes in ovarian Sertoli-Leydig cell tumor: A report from the International Pleuropulmonary Blastoma/DICER1 and Ovarian and Testicular Stromal Tumor Registries.
Nelson AT, Harris AK, Watson D, Kamihara J, Chen KS, Stall JN, Devins KM, Young RH, Olson DR, Mallinger PHR, Mitchell SG, Hoffman LM, Halliday G, Suleymanova AM, Glade Bender JL, Messinger YH, Herzog CE, Field AL, Frazier AL, Stewart DR, Dehner LP, Hill DA, Billmire DF, Schneider DT, Schultz KAP
Gynecol Oncol 2024 Jul;186:117-125. Epub 2024 Apr 23 doi: 10.1016/j.ygyno.2024.04.005. PMID: 38657450Free PMC Article
Sertoli-Leydig cell tumor of ovary in children: A report of two cases, including retiform variant.
Sarkar P, Sengupta M, Chatterjee U, Ghosh D
Indian J Pathol Microbiol 2021 Jul-Sep;64(3):559-562. doi: 10.4103/IJPM.IJPM_443_20. PMID: 34341273

Prognosis

Outcomes in ovarian Sertoli-Leydig cell tumor: A report from the International Pleuropulmonary Blastoma/DICER1 and Ovarian and Testicular Stromal Tumor Registries.
Nelson AT, Harris AK, Watson D, Kamihara J, Chen KS, Stall JN, Devins KM, Young RH, Olson DR, Mallinger PHR, Mitchell SG, Hoffman LM, Halliday G, Suleymanova AM, Glade Bender JL, Messinger YH, Herzog CE, Field AL, Frazier AL, Stewart DR, Dehner LP, Hill DA, Billmire DF, Schneider DT, Schultz KAP
Gynecol Oncol 2024 Jul;186:117-125. Epub 2024 Apr 23 doi: 10.1016/j.ygyno.2024.04.005. PMID: 38657450Free PMC Article

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