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Malignant Lung and Pleural Neoplasm

MedGen UID:
310977
•Concept ID:
C1708889
•
Neoplastic Process

Definition

A primary or metastatic malignant neoplasm that affects the lung and pleura. [from NCI]

Professional guidelines

PubMed

Malignant Pleural Effusion: Presentation, Diagnosis, and Management.
Gayen S
Am J Med 2022 Oct;135(10):1188-1192. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.017. PMID: 35576996
Malignant Pleural Effusion: Diagnosis and Management.
Ferreiro L, Suárez-Antelo J, Álvarez-Dobaño JM, Toubes ME, Riveiro V, Valdés L
Can Respir J 2020;2020:2950751. Epub 2020 Sep 23 doi: 10.1155/2020/2950751. PMID: 33273991Free PMC Article
Pleural Effusion in Adults-Etiology, Diagnosis, and Treatment.
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article

Recent clinical studies

Etiology

What's new in mesothelioma.
Ascoli V, Murer B, Nottegar A, Luchini C, Carella R, Calabrese F, Lunardi F, Cozzi I, Righi L
Pathologica 2018 Mar;110(1):12-28. PMID: 30259910
Malignant Mesothelioma and Its Non-Asbestos Causes.
Attanoos RL, Churg A, Galateau-Salle F, Gibbs AR, Roggli VL
Arch Pathol Lab Med 2018 Jun;142(6):753-760. Epub 2018 Feb 26 doi: 10.5858/arpa.2017-0365-RA. PMID: 29480760
A catalogue of treatment and technologies for malignant pleural mesothelioma.
Schunselaar LM, Quispel-Janssen JM, Neefjes JJ, Baas P
Expert Rev Anticancer Ther 2016;16(4):455-63. doi: 10.1586/14737140.2016.1162100. PMID: 26943000
Biomarkers and prognostic factors for malignant pleural mesothelioma.
Vigneri P, Martorana F, Manzella L, Stella S
Future Oncol 2015;11(24 Suppl):29-33. doi: 10.2217/fon.15.317. PMID: 26638920
Rare pleural tumors.
Erb CT, Johnson KM, Kim AW
Clin Chest Med 2013 Mar;34(1):113-36. doi: 10.1016/j.ccm.2012.12.001. PMID: 23411062

Diagnosis

Malignant Mesothelioma: Has Anything Changed?
Kim RY, Sterman DH, Haas AR
Semin Respir Crit Care Med 2019 Jun;40(3):347-360. Epub 2019 Sep 16 doi: 10.1055/s-0039-1693406. PMID: 31525810
What's new in mesothelioma.
Ascoli V, Murer B, Nottegar A, Luchini C, Carella R, Calabrese F, Lunardi F, Cozzi I, Righi L
Pathologica 2018 Mar;110(1):12-28. PMID: 30259910
Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment.
Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas I
Eur Respir Rev 2016 Dec;25(142):472-486. doi: 10.1183/16000617.0063-2016. PMID: 27903668Free PMC Article
Pleural neoplastic pathology.
Karpathiou G, Stefanou D, Froudarakis ME
Respir Med 2015 Aug;109(8):931-43. Epub 2015 May 21 doi: 10.1016/j.rmed.2015.05.014. PMID: 26048082
Malignant pleural mesothelioma.
Raja S, Murthy SC, Mason DP
Curr Oncol Rep 2011 Aug;13(4):259-64. doi: 10.1007/s11912-011-0177-9. PMID: 21573909

Therapy

Updates in Management of Malignant Pleural Mesothelioma.
John A, O'Sullivan H, Popat S
Curr Treat Options Oncol 2023 Dec;24(12):1758-1789. Epub 2023 Nov 17 doi: 10.1007/s11864-023-01148-2. PMID: 37975977
Target Therapy in Malignant Pleural Mesothelioma: Hope or Mirage?
Borea F, Franczak MA, Garcia M, Perrino M, Cordua N, Smolenski RT, Peters GJ, Dziadziuszko R, Santoro A, Zucali PA, Giovannetti E
Int J Mol Sci 2023 May 23;24(11) doi: 10.3390/ijms24119165. PMID: 37298116Free PMC Article
Immunotherapy approaches for malignant pleural mesothelioma.
Fennell DA, Dulloo S, Harber J
Nat Rev Clin Oncol 2022 Sep;19(9):573-584. Epub 2022 Jul 1 doi: 10.1038/s41571-022-00649-7. PMID: 35778611
Malignant Mesothelioma: Has Anything Changed?
Kim RY, Sterman DH, Haas AR
Semin Respir Crit Care Med 2019 Jun;40(3):347-360. Epub 2019 Sep 16 doi: 10.1055/s-0039-1693406. PMID: 31525810
Malignant pleural mesothelioma.
Raja S, Murthy SC, Mason DP
Curr Oncol Rep 2011 Aug;13(4):259-64. doi: 10.1007/s11912-011-0177-9. PMID: 21573909

Prognosis

DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma.
González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP
Mod Pathol 2022 Jan;35(1):4-22. Epub 2021 Oct 1 doi: 10.1038/s41379-021-00905-8. PMID: 34599283Free PMC Article
What's new in mesothelioma.
Ascoli V, Murer B, Nottegar A, Luchini C, Carella R, Calabrese F, Lunardi F, Cozzi I, Righi L
Pathologica 2018 Mar;110(1):12-28. PMID: 30259910
Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment.
Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas I
Eur Respir Rev 2016 Dec;25(142):472-486. doi: 10.1183/16000617.0063-2016. PMID: 27903668Free PMC Article
Pleural neoplastic pathology.
Karpathiou G, Stefanou D, Froudarakis ME
Respir Med 2015 Aug;109(8):931-43. Epub 2015 May 21 doi: 10.1016/j.rmed.2015.05.014. PMID: 26048082
Pleural malignancies.
Friedberg JS, Cengel KA
Semin Radiat Oncol 2010 Jul;20(3):208-14. doi: 10.1016/j.semradonc.2010.01.009. PMID: 20685584

Clinical prediction guides

Immunotherapy approaches for malignant pleural mesothelioma.
Fennell DA, Dulloo S, Harber J
Nat Rev Clin Oncol 2022 Sep;19(9):573-584. Epub 2022 Jul 1 doi: 10.1038/s41571-022-00649-7. PMID: 35778611
Genomics and Functional Genomics of Malignant Pleural Mesothelioma.
Cakiroglu E, Senturk S
Int J Mol Sci 2020 Sep 1;21(17) doi: 10.3390/ijms21176342. PMID: 32882916Free PMC Article
Malignant Pleural Effusion and Its Current Management: A Review.
Skok K, Hladnik G, Grm A, Crnjac A
Medicina (Kaunas) 2019 Aug 15;55(8) doi: 10.3390/medicina55080490. PMID: 31443309Free PMC Article
What's new in mesothelioma.
Ascoli V, Murer B, Nottegar A, Luchini C, Carella R, Calabrese F, Lunardi F, Cozzi I, Righi L
Pathologica 2018 Mar;110(1):12-28. PMID: 30259910
Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment.
Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas I
Eur Respir Rev 2016 Dec;25(142):472-486. doi: 10.1183/16000617.0063-2016. PMID: 27903668Free PMC Article

Recent systematic reviews

Sensitivity and complications of thoracentesis and thoracoscopy: a meta-analysis.
Martinez-Zayas G, Molina S, Ost DE
Eur Respir Rev 2022 Dec 31;31(166) Epub 2022 Dec 21 doi: 10.1183/16000617.0053-2022. PMID: 36543349Free PMC Article
ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma.
Scherpereel A, Opitz I, Berghmans T, Psallidas I, Glatzer M, Rigau D, Astoul P, Bölükbas S, Boyd J, Coolen J, De Bondt C, De Ruysscher D, Durieux V, Faivre-Finn C, Fennell D, Galateau-Salle F, Greillier L, Hoda MA, Klepetko W, Lacourt A, McElnay P, Maskell NA, Mutti L, Pairon JC, Van Schil P, van Meerbeeck JP, Waller D, Weder W, Cardillo G, Putora PM
Eur Respir J 2020 Jun;55(6) Epub 2020 Jun 11 doi: 10.1183/13993003.00953-2019. PMID: 32451346
Interventions for the management of malignant pleural effusions: a network meta-analysis.
Dipper A, Jones HE, Bhatnagar R, Preston NJ, Maskell N, Clive AO
Cochrane Database Syst Rev 2020 Apr 21;4(4):CD010529. doi: 10.1002/14651858.CD010529.pub3. PMID: 32315458Free PMC Article
Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline.
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
A systematic review and meta-analysis of surgical treatments for malignant pleural mesothelioma.
Cao C, Tian D, Park J, Allan J, Pataky KA, Yan TD
Lung Cancer 2014 Feb;83(2):240-5. Epub 2013 Dec 6 doi: 10.1016/j.lungcan.2013.11.026. PMID: 24360321

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