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Perifollicular fibroma

MedGen UID:
312363
Concept ID:
C1704236
Neoplastic Process
Synonym: Perifollicular fibromas
SNOMED CT: Perifollicular fibroma (128683008); Perifollicular fibroma (254698004); Perifolliculoma (254698004)
 
HPO: HP:0032225

Definition

Perifollicular fibroma is a rare cutaneous hamartoma that shows differentiation in the connective tissue sheath of hair follicles. It can occur as a solitary papule or as multiple lesions. Histologically, the lesion consists of a concentric arrangement of cellular fibrous tissue around a normal hair follicle. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerifollicular fibroma

Recent clinical studies

Etiology

Haneke E, Happle R
J Cutan Pathol 2024 Feb;51(2):170-175. Epub 2023 Aug 30 doi: 10.1111/cup.14522. PMID: 37649357
Anzai A, Halpern I, Rivitti-Machado MC
Am J Dermatopathol 2015 Sep;37(9):704-6. doi: 10.1097/DAD.0000000000000280. PMID: 25839891
Lencastre A, Ponte P, Apetato M, Nunes L, Lestre S
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):203-5. doi: 10.1590/abd1806-4841.20132199. PMID: 24346920Free PMC Article

Diagnosis

Wang Y, Allen PW
Adv Anat Pathol 2020 Nov;27(6):422-424. doi: 10.1097/PAP.0000000000000282. PMID: 33027095
Lencastre A, Ponte P, Apetato M, Nunes L, Lestre S
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):203-5. doi: 10.1590/abd1806-4841.20132199. PMID: 24346920Free PMC Article
Happle R
Am J Med Genet A 2012 Jun;158A(6):1247-51. Epub 2012 May 11 doi: 10.1002/ajmg.a.35330. PMID: 22581760
Cho S, Hahm JH
J Eur Acad Dermatol Venereol 1999 Jul;13(1):46-9. PMID: 10565630
Freeman RG, Chernosky ME
Arch Dermatol 1969 Jul;100(1):66-9. PMID: 5822359

Clinical prediction guides

Lencastre A, Ponte P, Apetato M, Nunes L, Lestre S
An Bras Dermatol 2013 Nov-Dec;88(6 Suppl 1):203-5. doi: 10.1590/abd1806-4841.20132199. PMID: 24346920Free PMC Article
Junkins-Hopkins JM, Cooper PH
J Cutan Pathol 1994 Oct;21(5):467-71. doi: 10.1111/j.1600-0560.1994.tb00291.x. PMID: 7868760

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