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Endometrial polyp

MedGen UID:
312370
Concept ID:
C1704273
Neoplastic Process
Synonyms: Endometrial Polyp; endometrial polyp; Endometrial Stromal Polyp; endometrial stromal polyp; endometrium polyp; Polyp of endometrium; Polyp of Endometrium; polyp of endometrium; Polyp of the Endometrium; polyp of the endometrium; polyp, endometrial stromal, benign
SNOMED CT: Endometrial polyp (1237359009); Polyp of endometrium (1237359009)
 
Monarch Initiative: MONDO:0006195

Definition

A benign nodular lesion protruding above the surface of the endometrium. It is composed of a fibrous stroma that contains thick-walled blood vessels and dilated endometrial glands. Polypectomy is the treatment of choice. Only few cases with recurrence have been reported. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Hiraoka T, Osuga Y, Hirota Y
J Obstet Gynaecol Res 2023 Oct;49(10):2397-2409. Epub 2023 Aug 1 doi: 10.1111/jog.15759. PMID: 37527810
Raz N, Feinmesser L, Moore O, Haimovich S
Minim Invasive Ther Allied Technol 2021 Oct;30(5):278-287. Epub 2021 Aug 6 doi: 10.1080/13645706.2021.1948867. PMID: 34355659
Vitale SG, Haimovich S, Laganà AS, Alonso L, Di Spiezio Sardo A, Carugno J; From the Global Community of Hysteroscopy Guidelines Committee
Eur J Obstet Gynecol Reprod Biol 2021 May;260:70-77. Epub 2021 Mar 13 doi: 10.1016/j.ejogrb.2021.03.017. PMID: 33756339

Recent clinical studies

Etiology

Vitale SG, Haimovich S, Laganà AS, Alonso L, Di Spiezio Sardo A, Carugno J; From the Global Community of Hysteroscopy Guidelines Committee
Eur J Obstet Gynecol Reprod Biol 2021 May;260:70-77. Epub 2021 Mar 13 doi: 10.1016/j.ejogrb.2021.03.017. PMID: 33756339
Van Den Bosch T, Verbakel JY, Valentin L, Wynants L, De Cock B, Pascual MA, Leone FPG, Sladkevicius P, Alcazar JL, Votino A, Fruscio R, Lanzani C, Van Holsbeke C, Rossi A, Jokubkiene L, Kudla M, Jakab A, Domali E, Epstein E, Van Pachterbeke C, Bourne T, Van Calster B, Timmerman D
Ultrasound Obstet Gynecol 2021 Jan;57(1):164-172. doi: 10.1002/uog.22109. PMID: 32484286
Lee M, Piao J, Jeon MJ
Yonsei Med J 2020 Apr;61(4):317-322. doi: 10.3349/ymj.2020.61.4.317. PMID: 32233174Free PMC Article
Salazar CA, Isaacson KB
J Minim Invasive Gynecol 2018 Feb;25(2):199-208. Epub 2017 Aug 10 doi: 10.1016/j.jmig.2017.08.009. PMID: 28803811
Mills AM, Longacre TA
Semin Diagn Pathol 2010 Nov;27(4):199-214. doi: 10.1053/j.semdp.2010.09.002. PMID: 21309256

Diagnosis

Raz N, Feinmesser L, Moore O, Haimovich S
Minim Invasive Ther Allied Technol 2021 Oct;30(5):278-287. Epub 2021 Aug 6 doi: 10.1080/13645706.2021.1948867. PMID: 34355659
Vitale SG, Haimovich S, Laganà AS, Alonso L, Di Spiezio Sardo A, Carugno J; From the Global Community of Hysteroscopy Guidelines Committee
Eur J Obstet Gynecol Reprod Biol 2021 May;260:70-77. Epub 2021 Mar 13 doi: 10.1016/j.ejogrb.2021.03.017. PMID: 33756339
Munro MG
Fertil Steril 2019 Apr;111(4):629-640. doi: 10.1016/j.fertnstert.2019.02.008. PMID: 30929720
Munro MG, Critchley HOD, Fraser IS; FIGO Menstrual Disorders Committee
Int J Gynaecol Obstet 2018 Dec;143(3):393-408. Epub 2018 Oct 10 doi: 10.1002/ijgo.12666. PMID: 30198563
Salazar CA, Isaacson KB
J Minim Invasive Gynecol 2018 Feb;25(2):199-208. Epub 2017 Aug 10 doi: 10.1016/j.jmig.2017.08.009. PMID: 28803811

Therapy

Rotenberg O, Doulaveris G, Fridman D, Renz M, Kaplan J, Xie X, Goldberg GL, Dar P
Maturitas 2023 Dec;178:107847. Epub 2023 Sep 9 doi: 10.1016/j.maturitas.2023.107847. PMID: 37717294
Zhong X, Li Y, Liang W, Hu Q, Zeng A, Ding M, Chen D, Xie M
BMC Womens Health 2023 May 6;23(1):236. doi: 10.1186/s12905-023-02339-7. PMID: 37149578Free PMC Article
Lee M, Piao J, Jeon MJ
Yonsei Med J 2020 Apr;61(4):317-322. doi: 10.3349/ymj.2020.61.4.317. PMID: 32233174Free PMC Article
Wolfman W
J Obstet Gynaecol Can 2018 May;40(5):e367-e377. doi: 10.1016/j.jogc.2018.03.005. PMID: 29731210
Wolfman W, Leyland N, Heywood M, Singh SS, Rittenberg DA, Soucy R, Allaire C, Awadalla A, Best C, Dunn S, Leroux N, Potestio F, Senikas V, Wallace S, Menzies R; Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2010 Oct;32(10):990-9. doi: 10.1016/s1701-2163(16)34690-4. PMID: 21176311

Prognosis

Hiraoka T, Osuga Y, Hirota Y
J Obstet Gynaecol Res 2023 Oct;49(10):2397-2409. Epub 2023 Aug 1 doi: 10.1111/jog.15759. PMID: 37527810
Hui P
Arch Pathol Lab Med 2023 Apr 1;147(4):413-417. doi: 10.5858/arpa.2021-0557-RA. PMID: 35512230
Yao L, Li C, Cheng J
Arch Gynecol Obstet 2022 Dec;306(6):2047-2054. Epub 2022 Aug 25 doi: 10.1007/s00404-022-06734-7. PMID: 36006486
Bahmyari S, Jamali Z, Khatami SH, Vakili O, Roozitalab M, Savardashtaki A, Solati A, Mousavi P, Shabaninejad Z, Vakili S, Behrouj H, Ghasemi H, Movahedpour A
Cell Biochem Funct 2021 Dec;39(8):955-969. Epub 2021 Oct 27 doi: 10.1002/cbf.3671. PMID: 34708430
Assem H, Rottmann D, Finkelstein A, Wang M, Ratner E, Santin AD, Buza N, Hui P
Hum Pathol 2021 Dec;118:1-8. Epub 2021 Sep 8 doi: 10.1016/j.humpath.2021.09.001. PMID: 34508766

Clinical prediction guides

Hiraoka T, Osuga Y, Hirota Y
J Obstet Gynaecol Res 2023 Oct;49(10):2397-2409. Epub 2023 Aug 1 doi: 10.1111/jog.15759. PMID: 37527810
Hui P
Arch Pathol Lab Med 2023 Apr 1;147(4):413-417. doi: 10.5858/arpa.2021-0557-RA. PMID: 35512230
Heremans R, Van Den Bosch T, Valentin L, Wynants L, Pascual MA, Fruscio R, Testa AC, Buonomo F, Guerriero S, Epstein E, Bourne T, Timmerman D, Leone FPG; IETA Consortium
Ultrasound Obstet Gynecol 2022 Aug;60(2):243-255. doi: 10.1002/uog.24910. PMID: 35385178
Van Den Bosch T, Verbakel JY, Valentin L, Wynants L, De Cock B, Pascual MA, Leone FPG, Sladkevicius P, Alcazar JL, Votino A, Fruscio R, Lanzani C, Van Holsbeke C, Rossi A, Jokubkiene L, Kudla M, Jakab A, Domali E, Epstein E, Van Pachterbeke C, Bourne T, Van Calster B, Timmerman D
Ultrasound Obstet Gynecol 2021 Jan;57(1):164-172. doi: 10.1002/uog.22109. PMID: 32484286
Wolfman W, Leyland N, Heywood M, Singh SS, Rittenberg DA, Soucy R, Allaire C, Awadalla A, Best C, Dunn S, Leroux N, Potestio F, Senikas V, Wallace S, Menzies R; Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2010 Oct;32(10):990-9. doi: 10.1016/s1701-2163(16)34690-4. PMID: 21176311

Recent systematic reviews

Simon JA, Ferenczy A, Black D, Castonguay A, Royer C, Marouf R, Beauchemin C
Menopause 2023 Aug 1;30(8):855-866. Epub 2023 Jun 27 doi: 10.1097/GME.0000000000002211. PMID: 37369079Free PMC Article
de Rijk SR, Steenbergen ME, Nieboer TE, Coppus SF
Obstet Gynecol 2016 Sep;128(3):519-525. doi: 10.1097/AOG.0000000000001566. PMID: 27500332
Pereira AK, Garcia MT, Pinheiro W, Ejzenberg D, Soares JM Jr, Baracat EC
Climacteric 2015;18(4):498-502. Epub 2014 Nov 19 doi: 10.3109/13697137.2014.966240. PMID: 25242379
Lee SC, Kaunitz AM, Sanchez-Ramos L, Rhatigan RM
Obstet Gynecol 2010 Nov;116(5):1197-205. doi: 10.1097/AOG.0b013e3181f74864. PMID: 20966706
Lieng M, Istre O, Qvigstad E
Acta Obstet Gynecol Scand 2010 Aug;89(8):992-1002. doi: 10.3109/00016349.2010.493196. PMID: 20528202

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