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Localized Resectable Adult Hepatocellular Carcinoma

MedGen UID:
313355
Concept ID:
C1708717
Neoplastic Process

Definition

A localized hepatocellular carcinoma that occurs during adulthood and it is amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Resectable Adult Hepatocellular Carcinoma

Professional guidelines

PubMed

Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, Fowers K, Lewandowski R, Padia SA
Hepatology 2021 Nov;74(5):2342-2352. Epub 2021 Jun 11 doi: 10.1002/hep.31819. PMID: 33739462Free PMC Article
Joliat GR, Allemann P, Labgaa I, Demartines N, Halkic N
Langenbecks Arch Surg 2017 Aug;402(5):737-744. Epub 2017 May 11 doi: 10.1007/s00423-017-1582-9. PMID: 28497194
Kassahun WT, Fangmann J, Harms J, Hauss J, Bartels M
Exp Clin Transplant 2006 Dec;4(2):549-58. PMID: 17238857

Recent clinical studies

Etiology

Tortajada P, Doamba R, Cano L, Ghallab M, Allard MA, Ciacio O, Pittau G, Salloum C, Cherqui D, Adam R, Sa Cunha A, Azoulay D, Pascale A, Vibert E, Golse N
Surgery 2022 Dec;172(6):1704-1711. Epub 2022 Oct 12 doi: 10.1016/j.surg.2022.08.012. PMID: 36241470
Kirimker EO, Kirac AT, Celik SU, Boztug CY, Kaya MB, Balci D, Karayalcin MK
Medicina (Kaunas) 2022 Sep 19;58(9) doi: 10.3390/medicina58091305. PMID: 36143982Free PMC Article
Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, Fowers K, Lewandowski R, Padia SA
Hepatology 2021 Nov;74(5):2342-2352. Epub 2021 Jun 11 doi: 10.1002/hep.31819. PMID: 33739462Free PMC Article
Akcam AT, Saritas AG, Ulku A, Rencuzogullari A
Transplant Proc 2019 May;51(4):1147-1152. Epub 2019 Feb 8 doi: 10.1016/j.transproceed.2019.01.093. PMID: 31101189
Chun YS, Zimmitti G
Recent Results Cancer Res 2013;190:101-10. doi: 10.1007/978-3-642-16037-0_7. PMID: 22941016

Diagnosis

Fraquelli M, Nadarevic T, Colli A, Manzotti C, Giljaca V, Miletic D, Štimac D, Casazza G
Cochrane Database Syst Rev 2022 Sep 2;9(9):CD013483. doi: 10.1002/14651858.CD013483.pub2. PMID: 36053210Free PMC Article
Nadarevic T, Colli A, Giljaca V, Fraquelli M, Casazza G, Manzotti C, Štimac D, Miletic D
Cochrane Database Syst Rev 2022 May 6;5(5):CD014798. doi: 10.1002/14651858.CD014798.pub2. PMID: 35521901Free PMC Article
Ding J, Wen Z
BMC Cancer 2021 Oct 29;21(1):1157. doi: 10.1186/s12885-021-08904-3. PMID: 34715816Free PMC Article
Marasco G, Colecchia A, Colli A, Ravaioli F, Casazza G, Bacchi Reggiani ML, Cucchetti A, Cescon M, Festi D
J Hepatol 2019 Mar;70(3):440-448. Epub 2018 Oct 31 doi: 10.1016/j.jhep.2018.10.022. PMID: 30389551
Chun YS, Zimmitti G
Recent Results Cancer Res 2013;190:101-10. doi: 10.1007/978-3-642-16037-0_7. PMID: 22941016

Therapy

Chiang CL, Chiu KWH, Chan KSK, Lee FAS, Li JCB, Wan CWS, Dai WC, Lam TC, Chen W, Wong NSM, Cheung ALY, Lee VWY, Lau VWH, El Helali A, Man K, Kong FMS, Lo CM, Chan AC
Lancet Gastroenterol Hepatol 2023 Feb;8(2):169-178. Epub 2022 Dec 15 doi: 10.1016/S2468-1253(22)00339-9. PMID: 36529152
Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, Fowers K, Lewandowski R, Padia SA
Hepatology 2021 Nov;74(5):2342-2352. Epub 2021 Jun 11 doi: 10.1002/hep.31819. PMID: 33739462Free PMC Article
Marasco G, Colecchia A, Colli A, Ravaioli F, Casazza G, Bacchi Reggiani ML, Cucchetti A, Cescon M, Festi D
J Hepatol 2019 Mar;70(3):440-448. Epub 2018 Oct 31 doi: 10.1016/j.jhep.2018.10.022. PMID: 30389551
Vilgrain V, Pereira H, Assenat E, Guiu B, Ilonca AD, Pageaux GP, Sibert A, Bouattour M, Lebtahi R, Allaham W, Barraud H, Laurent V, Mathias E, Bronowicki JP, Tasu JP, Perdrisot R, Silvain C, Gerolami R, Mundler O, Seitz JF, Vidal V, Aubé C, Oberti F, Couturier O, Brenot-Rossi I, Raoul JL, Sarran A, Costentin C, Itti E, Luciani A, Adam R, Lewin M, Samuel D, Ronot M, Dinut A, Castera L, Chatellier G; SARAH Trial Group
Lancet Oncol 2017 Dec;18(12):1624-1636. Epub 2017 Oct 26 doi: 10.1016/S1470-2045(17)30683-6. PMID: 29107679
Bruix J, Takayama T, Mazzaferro V, Chau GY, Yang J, Kudo M, Cai J, Poon RT, Han KH, Tak WY, Lee HC, Song T, Roayaie S, Bolondi L, Lee KS, Makuuchi M, Souza F, Berre MA, Meinhardt G, Llovet JM; STORM investigators
Lancet Oncol 2015 Oct;16(13):1344-54. Epub 2015 Sep 8 doi: 10.1016/S1470-2045(15)00198-9. PMID: 26361969

Prognosis

Ding J, Wen Z
BMC Cancer 2021 Oct 29;21(1):1157. doi: 10.1186/s12885-021-08904-3. PMID: 34715816Free PMC Article
Yoh T, Seo S, Taura K, Iguchi K, Ogiso S, Fukumitsu K, Ishii T, Kaido T, Uemoto S
Ann Surg 2021 Apr 1;273(4):792-799. doi: 10.1097/SLA.0000000000003358. PMID: 31058698
Li M, Wang Z, Cao J, Han B, Zou H, Zang Y, Wu L
Eur J Surg Oncol 2019 Sep;45(9):1684-1690. Epub 2019 Apr 13 doi: 10.1016/j.ejso.2019.04.008. PMID: 31027944
Chun YS, Zimmitti G
Recent Results Cancer Res 2013;190:101-10. doi: 10.1007/978-3-642-16037-0_7. PMID: 22941016
Schwarz RE, Smith DD
Am J Surg 2008 Jun;195(6):829-36. Epub 2008 Apr 23 doi: 10.1016/j.amjsurg.2007.10.010. PMID: 18436176

Clinical prediction guides

Ding J, Wen Z
BMC Cancer 2021 Oct 29;21(1):1157. doi: 10.1186/s12885-021-08904-3. PMID: 34715816Free PMC Article
Lin WP, Xing KL, Fu JC, Ling YH, Li SH, Yu WS, Zhang YF, Zhong C, Wang JH, Chen ZY, Lu LH, Wei W, Guo RP
JAMA Netw Open 2021 Sep 1;4(9):e2125055. doi: 10.1001/jamanetworkopen.2021.25055. PMID: 34515782Free PMC Article
Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, Fowers K, Lewandowski R, Padia SA
Hepatology 2021 Nov;74(5):2342-2352. Epub 2021 Jun 11 doi: 10.1002/hep.31819. PMID: 33739462Free PMC Article
Marasco G, Colecchia A, Colli A, Ravaioli F, Casazza G, Bacchi Reggiani ML, Cucchetti A, Cescon M, Festi D
J Hepatol 2019 Mar;70(3):440-448. Epub 2018 Oct 31 doi: 10.1016/j.jhep.2018.10.022. PMID: 30389551
Hu B, Yang XR, Xu Y, Sun YF, Sun C, Guo W, Zhang X, Wang WM, Qiu SJ, Zhou J, Fan J
Clin Cancer Res 2014 Dec 1;20(23):6212-22. Epub 2014 Sep 30 doi: 10.1158/1078-0432.CCR-14-0442. PMID: 25271081

Recent systematic reviews

Fraquelli M, Nadarevic T, Colli A, Manzotti C, Giljaca V, Miletic D, Štimac D, Casazza G
Cochrane Database Syst Rev 2022 Sep 2;9(9):CD013483. doi: 10.1002/14651858.CD013483.pub2. PMID: 36053210Free PMC Article
Gavriilidis P, Askari A, Azoulay D
HPB (Oxford) 2017 Jan;19(1):3-9. Epub 2016 Oct 27 doi: 10.1016/j.hpb.2016.10.003. PMID: 28341429
Abdel-Rahman O, Elsayed Z
Cochrane Database Syst Rev 2017 Mar 7;3(3):CD011314. doi: 10.1002/14651858.CD011314.pub2. PMID: 28267205Free PMC Article
Qiao W, Yu F, Wu L, Li B, Zhou Y
BMC Gastroenterol 2016 Jan 28;16:11. doi: 10.1186/s12876-016-0427-2. PMID: 26822229Free PMC Article
Thomasset SC, Dennison AR, Garcea G
World J Surg 2015 May;39(5):1150-60. doi: 10.1007/s00268-015-2956-1. PMID: 25634340

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