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Anorexia nervosa

MedGen UID:
316
Concept ID:
C0003125
Mental or Behavioral Dysfunction
Synonyms: Anorexia Nervosa; Anorexia Nervosas; Nervosa, Anorexia; Nervosas, Anorexia
SNOMED CT: AN - Anorexia nervosa (56882008); Anorexia nervosa (56882008)
 
Monarch Initiative: MONDO:0005351
Orphanet: ORPHA36297

Definition

A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnorexia nervosa

Professional guidelines

PubMed

Muratore AF, Attia E
Curr Psychiatry Rep 2022 Jul;24(7):345-351. Epub 2022 May 16 doi: 10.1007/s11920-022-01340-5. PMID: 35576089Free PMC Article
Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U
Lancet Psychiatry 2015 Dec;2(12):1099-111. Epub 2015 Oct 27 doi: 10.1016/S2215-0366(15)00356-9. PMID: 26514083
Hartman D
Postgrad Med J 1995 Dec;71(842):712-6. doi: 10.1136/pgmj.71.842.712. PMID: 8552532Free PMC Article

Curated

UK NICE Guideline NG69, Eating disorders: recognition and treatment, 2020

Recent clinical studies

Etiology

van Eeden AE, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2021 Nov 1;34(6):515-524. doi: 10.1097/YCO.0000000000000739. PMID: 34419970Free PMC Article
Neale J, Hudson LD
Br J Hosp Med (Lond) 2020 Jun 2;81(6):1-8. Epub 2020 Jun 1 doi: 10.12968/hmed.2020.0099. PMID: 32589532
Marucci S, Ragione LD, De Iaco G, Mococci T, Vicini M, Guastamacchia E, Triggiani V
Endocr Metab Immune Disord Drug Targets 2018;18(4):316-324. doi: 10.2174/1871530318666180213111637. PMID: 29437020
Moskowitz L, Weiselberg E
Curr Probl Pediatr Adolesc Health Care 2017 Apr;47(4):70-84. doi: 10.1016/j.cppeds.2017.02.003. PMID: 28532965
Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U
Lancet Psychiatry 2015 Dec;2(12):1099-111. Epub 2015 Oct 27 doi: 10.1016/S2215-0366(15)00356-9. PMID: 26514083

Diagnosis

Mitchell JE, Peterson CB
N Engl J Med 2020 Apr 2;382(14):1343-1351. doi: 10.1056/NEJMcp1803175. PMID: 32242359
Peterson K, Fuller R
Nursing 2019 Oct;49(10):24-30. doi: 10.1097/01.NURSE.0000580640.43071.15. PMID: 31568077
Moskowitz L, Weiselberg E
Curr Probl Pediatr Adolesc Health Care 2017 Apr;47(4):70-84. doi: 10.1016/j.cppeds.2017.02.003. PMID: 28532965
Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U
Lancet Psychiatry 2015 Dec;2(12):1099-111. Epub 2015 Oct 27 doi: 10.1016/S2215-0366(15)00356-9. PMID: 26514083
Hartman D
Postgrad Med J 1995 Dec;71(842):712-6. doi: 10.1136/pgmj.71.842.712. PMID: 8552532Free PMC Article

Therapy

Fornaro M, Mondin AM, Billeci M, Fusco A, De Prisco M, Caiazza C, Micanti F, Calati R, Carvalho AF, de Bartolomeis A
J Affect Disord 2023 Oct 1;338:526-545. Epub 2023 Jun 30 doi: 10.1016/j.jad.2023.06.068. PMID: 37393954
Han R, Bian Q, Chen H
Brain Behav 2022 Feb;12(2):e2498. Epub 2022 Jan 12 doi: 10.1002/brb3.2498. PMID: 35020271Free PMC Article
Fisher CA, Skocic S, Rutherford KA, Hetrick SE
Cochrane Database Syst Rev 2019 May 1;5(5):CD004780. doi: 10.1002/14651858.CD004780.pub4. PMID: 31041816Free PMC Article
Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U
Lancet Psychiatry 2015 Dec;2(12):1099-111. Epub 2015 Oct 27 doi: 10.1016/S2215-0366(15)00356-9. PMID: 26514083
Vancampfort D, Vanderlinden J, De Hert M, Soundy A, Adámkova M, Skjaerven LH, Catalán-Matamoros D, Lundvik Gyllensten A, Gómez-Conesa A, Probst M
Disabil Rehabil 2014;36(8):628-34. Epub 2013 Jul 4 doi: 10.3109/09638288.2013.808271. PMID: 23826882

Prognosis

van Eeden AE, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2021 Nov 1;34(6):515-524. doi: 10.1097/YCO.0000000000000739. PMID: 34419970Free PMC Article
Neale J, Hudson LD
Br J Hosp Med (Lond) 2020 Jun 2;81(6):1-8. Epub 2020 Jun 1 doi: 10.12968/hmed.2020.0099. PMID: 32589532
Dobrescu SR, Dinkler L, Gillberg C, Råstam M, Gillberg C, Wentz E
Br J Psychiatry 2020 Feb;216(2):97-104. doi: 10.1192/bjp.2019.113. PMID: 31113504Free PMC Article
Smink FR, van Hoeken D, Hoek HW
Curr Opin Psychiatry 2013 Nov;26(6):543-8. doi: 10.1097/YCO.0b013e328365a24f. PMID: 24060914
Smink FR, van Hoeken D, Hoek HW
Curr Psychiatry Rep 2012 Aug;14(4):406-14. doi: 10.1007/s11920-012-0282-y. PMID: 22644309Free PMC Article

Clinical prediction guides

Cuntz U, Quadflieg N, Voderholzer U
Nutrients 2023 Jul 24;15(14) doi: 10.3390/nu15143262. PMID: 37513680Free PMC Article
Sravanti L, Velusamy AJP, Karki U, Kommu JVS, Girimaji SC
Asian J Psychiatr 2022 May;71:103077. Epub 2022 Mar 11 doi: 10.1016/j.ajp.2022.103077. PMID: 35299144
Gorwood P, Duriez P, Lengvenyte A, Guillaume S, Criquillion S; FFAB network
Psychiatry Res 2019 Nov;281:112561. Epub 2019 Sep 9 doi: 10.1016/j.psychres.2019.112561. PMID: 31521839
Rosen E, Bakshi N, Watters A, Rosen HR, Mehler PS
Dig Dis Sci 2017 Nov;62(11):2977-2981. Epub 2017 Sep 20 doi: 10.1007/s10620-017-4766-9. PMID: 28932925
Raevuori A, Keski-Rahkonen A, Hoek HW
Curr Opin Psychiatry 2014 Nov;27(6):426-30. doi: 10.1097/YCO.0000000000000113. PMID: 25226158

Recent systematic reviews

Minano-Garrido EJ, Catalan-Matamoros D, Gómez-Conesa A
Int J Environ Res Public Health 2022 Oct 26;19(21) doi: 10.3390/ijerph192113921. PMID: 36360815Free PMC Article
Monteleone AM, Pellegrino F, Croatto G, Carfagno M, Hilbert A, Treasure J, Wade T, Bulik CM, Zipfel S, Hay P, Schmidt U, Castellini G, Favaro A, Fernandez-Aranda F, Il Shin J, Voderholzer U, Ricca V, Moretti D, Busatta D, Abbate-Daga G, Ciullini F, Cascino G, Monaco F, Correll CU, Solmi M
Neurosci Biobehav Rev 2022 Nov;142:104857. Epub 2022 Sep 6 doi: 10.1016/j.neubiorev.2022.104857. PMID: 36084848Free PMC Article
Bilbao A, Spanagel R
BMC Med 2022 Aug 19;20(1):259. doi: 10.1186/s12916-022-02459-1. PMID: 35982439Free PMC Article
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
Nikolova VL, Smith MRB, Hall LJ, Cleare AJ, Stone JM, Young AH
JAMA Psychiatry 2021 Dec 1;78(12):1343-1354. doi: 10.1001/jamapsychiatry.2021.2573. PMID: 34524405Free PMC Article

Supplemental Content

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    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE Guideline NG69, Eating disorders: recognition and treatment, 2020

    Consumer resources

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