U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Glenoid fossa hypoplasia

MedGen UID:
331731
Concept ID:
C1834384
Finding
Synonyms: Glenoid hypoplasia; Hypoplastic glenoid fossa
 
HPO: HP:0006633

Definition

Underdevelopment of the glenoid fossa, which is the cavity in the lateral part of the scapula which articulates with the head of the humerus. [from HPO]

Term Hierarchy

Conditions with this feature

Nail-patella syndrome
MedGen UID:
10257
Concept ID:
C0027341
Disease or Syndrome
Nail-patella syndrome (NPS) (previously referred to as Fong's disease), encompasses the classic clinical tetrad of changes in the nails, knees, and elbows, and the presence of iliac horns. Nail changes are the most constant feature of NPS. Nails may be absent, hypoplastic, or dystrophic; ridged longitudinally or horizontally; pitted; discolored; separated into two halves by a longitudinal cleft or ridge of skin; and thin or (less often) thickened. The patellae may be small, irregularly shaped, or absent. Elbow abnormalities may include limitation of extension, pronation, and supination; cubitus valgus; and antecubital pterygia. Iliac horns are bilateral, conical, bony processes that project posteriorly and laterally from the central part of the iliac bones of the pelvis. Renal involvement, first manifest as proteinuria with or without hematuria, occurs in 30%-50% of affected individuals; end-stage renal disease occurs up to 15% of affected individuals. Primary open-angle glaucoma and ocular hypertension occur at increased frequency and at a younger age than in the general population.
Van den Ende-Gupta syndrome
MedGen UID:
322127
Concept ID:
C1833136
Disease or Syndrome
Van den Ende-Gupta syndrome (VDEGS) is an autosomal recessive disorder characterized by severe contractual arachnodactyly from birth and distinctive facial dysmorphism, including triangular face, malar hypoplasia, narrow nose, everted lips, and blepharophimosis. Skeletal anomalies include slender ribs, hooked clavicles, and dislocated radial head. There is no neurologic involvement (summary by Patel et al., 2014).
Dysostosis multiplex, Ain-Naz type
MedGen UID:
1780944
Concept ID:
C5444223
Disease or Syndrome
The Ain-Naz type of dysostosis multiplex (DMAN) is a severe progressive skeletal dysplasia with features of a metabolic disorder. Patients exhibit marked short stature, coarse facies with broad nose and prominent lips, and a distended abdomen, and experience severe physical disability. Early death has been observed in some patients (Ain et al., 2021).

Professional guidelines

PubMed

Miller RS, Jahrsdoerfer RA, Hashisaki GT, Kesser BW
Otol Neurotol 2006 Feb;27(2):189-92. doi: 10.1097/01.mao.0000185274.45507.2d. PMID: 16436988

Recent clinical studies

Etiology

Shu KY, Liu W, Zhao JL, Zhang ZY, Xu X, Shan BG, Tang XJ
J Craniofac Surg 2023 Mar-Apr 01;34(2):438-442. Epub 2022 Jul 22 doi: 10.1097/SCS.0000000000008777. PMID: 35864577
Burnier M, Le Hanneur M, Cambon-Binder A, Belkheyar Z
J Shoulder Elbow Surg 2019 Jul;28(7):1347-1355. Epub 2019 Apr 10 doi: 10.1016/j.jse.2018.12.016. PMID: 30981548
Kim JY, Kim BJ, Park KH, Huh JK
Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Dec;122(6):772-780. Epub 2016 Aug 31 doi: 10.1016/j.oooo.2016.08.017. PMID: 27727116
De Clerck H, Nguyen T, de Paula LK, Cevidanes L
Am J Orthod Dentofacial Orthop 2012 Jul;142(1):25-31. doi: 10.1016/j.ajodo.2012.01.017. PMID: 22748987Free PMC Article
Trout TE, Resnick D
Skeletal Radiol 1996 Jan;25(1):37-40. doi: 10.1007/s002560050029. PMID: 8717117

Diagnosis

Albano D, Messina C, Sconfienza LM
Magn Reson Imaging Clin N Am 2020 May;28(2):211-221. Epub 2020 Feb 17 doi: 10.1016/j.mric.2019.12.005. PMID: 32241659
Iwanaga J, Kikuta S, Nakamura M, Koba A, Ogata K, Toyofuku S, Tubbs RS, Kusukawa J
Int J Oral Maxillofac Surg 2017 Dec;46(12):1552-1556. Epub 2017 Jun 26 doi: 10.1016/j.ijom.2017.06.003. PMID: 28663018
Lin H, Zhu P, Lin Y, Wan S, Shu X, Xu Y, Zheng Y
Head Face Med 2013 Dec 20;9:42. doi: 10.1186/1746-160X-9-42. PMID: 24354862Free PMC Article
Chloros GD, Haar PJ, Loughran TP, Hayes CW
Clin Sports Med 2013 Jul;32(3):361-90. Epub 2013 May 17 doi: 10.1016/j.csm.2013.04.001. PMID: 23773873
Nath RK, Paizi M, Melcher SE, Farina KL
Magn Reson Imaging 2007 Nov;25(9):1277-82. Epub 2007 Apr 19 doi: 10.1016/j.mri.2007.02.008. PMID: 17448618

Therapy

Bobko A, Edwards G, Rodriguez J, Southworth T, Miller A, Peresada D, Onsen L, Goldberg B
Int Orthop 2021 Jun;45(6):1567-1572. Epub 2021 Apr 20 doi: 10.1007/s00264-021-05047-9. PMID: 33877406
Li W, Wei L, Wang F, Cheng Y, Li B
J Craniofac Surg 2018 Oct;29(7):e665-e667. doi: 10.1097/SCS.0000000000004748. PMID: 30052611
Kany J, Katz D
Eur J Orthop Surg Traumatol 2013 May;23(4):379-85. Epub 2012 Nov 2 doi: 10.1007/s00590-012-1118-5. PMID: 23412244
Acarturk TO, Azari K, Mooney M, Chang T, Losken HW, Bradley JP
Plast Reconstr Surg 2005 Jan;115(1):172-82. PMID: 15622248
Matsumoto K, Nakanishi H, Koizumi Y, Yamano M, Hashimoto I, Satake S, Moriyama K
J Craniofac Surg 2004 May;15(3):464-8. doi: 10.1097/00001665-200405000-00024. PMID: 15111811

Prognosis

ShanYong Z, Liu H, Yang C, Zhang X, Abdelrehem A, Zheng J, Jiao Z, Chen M, Qiu Y
J Craniomaxillofac Surg 2015 Jul;43(6):934-9. Epub 2015 Apr 1 doi: 10.1016/j.jcms.2015.03.028. PMID: 26003591
Breton A, Mainard L, De Gaspéri M, Barbary S, Maurice E, Dautel G
Orthop Traumatol Surg Res 2012 Oct;98(6):638-44. Epub 2012 Sep 14 doi: 10.1016/j.otsr.2012.06.013. PMID: 22981703
Göksu N, Kemaloğlu YK, Köybaşioğlu A, Ileri F, Ozbilen S, Akyildiz N
Am J Otol 1997 May;18(3):304-6. PMID: 9149822
Chiossone E
Am J Otol 1985 May;6(3):237-42. PMID: 4003533
Munro IR
Plast Reconstr Surg 1980 Nov;66(5):699-710. doi: 10.1097/00006534-198011000-00005. PMID: 7001516

Clinical prediction guides

Shu KY, Liu W, Zhao JL, Zhang ZY, Xu X, Shan BG, Tang XJ
J Craniofac Surg 2023 Mar-Apr 01;34(2):438-442. Epub 2022 Jul 22 doi: 10.1097/SCS.0000000000008777. PMID: 35864577
Burnier M, Le Hanneur M, Cambon-Binder A, Belkheyar Z
J Shoulder Elbow Surg 2019 Jul;28(7):1347-1355. Epub 2019 Apr 10 doi: 10.1016/j.jse.2018.12.016. PMID: 30981548
Iwanaga J, Kikuta S, Nakamura M, Koba A, Ogata K, Toyofuku S, Tubbs RS, Kusukawa J
Int J Oral Maxillofac Surg 2017 Dec;46(12):1552-1556. Epub 2017 Jun 26 doi: 10.1016/j.ijom.2017.06.003. PMID: 28663018
De Clerck H, Nguyen T, de Paula LK, Cevidanes L
Am J Orthod Dentofacial Orthop 2012 Jul;142(1):25-31. doi: 10.1016/j.ajodo.2012.01.017. PMID: 22748987Free PMC Article
Cohen MM Jr, Kreiborg S
Am J Med Genet 1993 Oct 1;47(5):624-32. doi: 10.1002/ajmg.1320470509. PMID: 8266987

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...