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Rounded epiphyses

MedGen UID:
338090
•Concept ID:
C1850632
•
Finding
Synonym: Rounded end part of bone
 
HPO: HP:0006026

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRounded epiphyses

Professional guidelines

PubMed

Clear cell chondrosarcoma: a review of clinicopathologic characteristics, differential diagnoses, and patient management.
Alexiev BA, Vormittag-Nocito ER, Peabody TD, Samet J, Laskin WB
Hum Pathol 2023 Sep;139:126-134. Epub 2023 Jun 16 doi: 10.1016/j.humpath.2023.06.004. PMID: 37805864
Management of anterior cruciate ligament tears in skeletally immature athletes.
Ludwig M, Atanda A Jr
Phys Sportsmed 2015 Nov;43(4):440-7. Epub 2015 Aug 31 doi: 10.1080/00913847.2015.1084213. PMID: 26329291
Prenatal diagnosis of achondroplasia: new specific signs.
Boulet S, Althuser M, Nugues F, Schaal JP, Jouk PS
Prenat Diagn 2009 Jul;29(7):697-702. doi: 10.1002/pd.2280. PMID: 19399756

Recent clinical studies

Etiology

Chondroblastoma: Cytomorphologic Analysis of 10 Cases with Review of the Literature.
Saoud C, Wakely PE Jr, Pantanowitz L, Siddiqui MT, Ali SZ
Acta Cytol 2023;67(4):413-424. Epub 2023 Jan 4 doi: 10.1159/000528932. PMID: 36599325
Growth impairment in mucopolysaccharidoses.
Melbouci M, Mason RW, Suzuki Y, Fukao T, Orii T, Tomatsu S
Mol Genet Metab 2018 May;124(1):1-10. Epub 2018 Mar 16 doi: 10.1016/j.ymgme.2018.03.004. PMID: 29627275Free PMC Article
Small cell tumors of bone.
Li S, Siegal GP
Adv Anat Pathol 2010 Jan;17(1):1-11. doi: 10.1097/PAP.0b013e3181bb6b9c. PMID: 20032633
Osteosclerotic metaphyseal dysplasia.
Nishimura G, Kozlowski K
Pediatr Radiol 1993;23(6):450-2. doi: 10.1007/BF02012448. PMID: 8255649
Benign Chondroblastoma.
Kumar VP, Pang M, Pho RW
Ann Acad Med Singap 1981 Jul;10(3):317-22. PMID: 7332302

Diagnosis

Clear cell chondrosarcoma: a review of clinicopathologic characteristics, differential diagnoses, and patient management.
Alexiev BA, Vormittag-Nocito ER, Peabody TD, Samet J, Laskin WB
Hum Pathol 2023 Sep;139:126-134. Epub 2023 Jun 16 doi: 10.1016/j.humpath.2023.06.004. PMID: 37805864
Chondroblastoma: Cytomorphologic Analysis of 10 Cases with Review of the Literature.
Saoud C, Wakely PE Jr, Pantanowitz L, Siddiqui MT, Ali SZ
Acta Cytol 2023;67(4):413-424. Epub 2023 Jan 4 doi: 10.1159/000528932. PMID: 36599325
Pubertal disorders and bone maturation.
Lazar L, Phillip M
Endocrinol Metab Clin North Am 2012 Dec;41(4):805-25. doi: 10.1016/j.ecl.2012.08.003. PMID: 23099272
Small cell tumors of bone.
Li S, Siegal GP
Adv Anat Pathol 2010 Jan;17(1):1-11. doi: 10.1097/PAP.0b013e3181bb6b9c. PMID: 20032633
Hypermobility of the first ray.
Myerson MS, Badekas A
Foot Ankle Clin 2000 Sep;5(3):469-84. PMID: 11232392

Therapy

Denosumab-treated giant cell tumor of bone. Its histologic spectrum and potential diagnostic pitfalls.
Roitman PD, Jauk F, Farfalli GL, Albergo JI, Aponte-Tinao LA
Hum Pathol 2017 May;63:89-97. Epub 2017 Feb 22 doi: 10.1016/j.humpath.2017.02.008. PMID: 28235628
The physiopathology of avascular necrosis of the femoral head: an update.
Guerado E, Caso E
Injury 2016 Dec;47 Suppl 6:S16-S26. doi: 10.1016/S0020-1383(16)30835-X. PMID: 28040082
Pubertal disorders and bone maturation.
Lazar L, Phillip M
Endocrinol Metab Clin North Am 2012 Dec;41(4):805-25. doi: 10.1016/j.ecl.2012.08.003. PMID: 23099272
Osseous manifestations of tuberculosis in children.
Rasool MN
J Pediatr Orthop 2001 Nov-Dec;21(6):749-55. PMID: 11675548
Hypermobility of the first ray.
Myerson MS, Badekas A
Foot Ankle Clin 2000 Sep;5(3):469-84. PMID: 11232392

Prognosis

Imaging Review of Normal and Abnormal Skeletal Maturation.
Augusto ACL, Goes PCK, Flores DV, Costa MAF, Takahashi MS, Rodrigues ACO, Padula LC, Gasparetto TD, Nogueira-Barbosa MH, Aihara AY
Radiographics 2022 May-Jun;42(3):861-879. Epub 2022 Feb 25 doi: 10.1148/rg.210088. PMID: 35213260
Growth impairment in mucopolysaccharidoses.
Melbouci M, Mason RW, Suzuki Y, Fukao T, Orii T, Tomatsu S
Mol Genet Metab 2018 May;124(1):1-10. Epub 2018 Mar 16 doi: 10.1016/j.ymgme.2018.03.004. PMID: 29627275Free PMC Article
Pubertal disorders and bone maturation.
Lazar L, Phillip M
Endocrinol Metab Clin North Am 2012 Dec;41(4):805-25. doi: 10.1016/j.ecl.2012.08.003. PMID: 23099272
Osteosclerotic metaphyseal dysplasia.
Nishimura G, Kozlowski K
Pediatr Radiol 1993;23(6):450-2. doi: 10.1007/BF02012448. PMID: 8255649
Chondroblastoma of bone.
Nolan DJ, Middlemiss H
Clin Radiol 1975 Jul;26(3):343-50. doi: 10.1016/s0009-9260(75)80075-4. PMID: 1059512

Clinical prediction guides

Imaging Review of Normal and Abnormal Skeletal Maturation.
Augusto ACL, Goes PCK, Flores DV, Costa MAF, Takahashi MS, Rodrigues ACO, Padula LC, Gasparetto TD, Nogueira-Barbosa MH, Aihara AY
Radiographics 2022 May-Jun;42(3):861-879. Epub 2022 Feb 25 doi: 10.1148/rg.210088. PMID: 35213260
Pubertal disorders and bone maturation.
Lazar L, Phillip M
Endocrinol Metab Clin North Am 2012 Dec;41(4):805-25. doi: 10.1016/j.ecl.2012.08.003. PMID: 23099272
The nature of giant cell tumor of bone.
Wülling M, Engels C, Jesse N, Werner M, Delling G, Kaiser E
J Cancer Res Clin Oncol 2001 Aug;127(8):467-74. doi: 10.1007/s004320100234. PMID: 11501745
Perinatal lethal hypophosphatasia; clinical, radiologic and morphologic findings.
Shohat M, Rimoin DL, Gruber HE, Lachman RS
Pediatr Radiol 1991;21(6):421-7. doi: 10.1007/BF02026677. PMID: 1749675
Brachyolmia: radiographic and genetic evidence of heterogeneity.
Shohat M, Lachman R, Gruber HE, Rimoin DL
Am J Med Genet 1989 Jun;33(2):209-19. doi: 10.1002/ajmg.1320330214. PMID: 2669482

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