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Cartilaginous ossification of nose

MedGen UID:
340915
•Concept ID:
C1855616
•
Finding
Synonym: Cartilaginous nasal ossification
 
HPO: HP:0005275

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCartilaginous ossification of nose

Conditions with this feature

Keutel syndrome
MedGen UID:
383722
•Concept ID:
C1855607
•
Disease or Syndrome
Keutel syndrome (KTLS) is an autosomal recessive disorder characterized by multiple peripheral pulmonary stenoses, brachytelephalangy, inner ear deafness, and abnormal cartilage ossification or calcification (summary by Khosroshahi et al., 2014).
See: Condition Record
Keutel syndrome

Recent clinical studies

Etiology

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review.
Jiang H, Yang X, Guo Y
Ear Nose Throat J 2024 Apr;103(4):NP226-NP228. Epub 2021 Oct 12 doi: 10.1177/01455613211051662. PMID: 34636258
Use of hyaluronic acid matrix in dorsal augmentation rhinoplasty.
Erisgin Z, Hizli O, Yildirim G, Sivrikaya C, Sarisoy AB, Avci Y, Ozcan KM
Biotech Histochem 2023 Nov;98(8):561-566. Epub 2023 Aug 30 doi: 10.1080/10520295.2023.2248889. PMID: 37646474
Nasal Construction in Congenital Arhinia Due to Novel SMCHD1 Gene Variant.
Bargiela M, Kueper J, Serebrakian AT, Browne MR, Brogna S, Peacock ZS, Bojovic B, Shaw ND, Liao EC
J Craniofac Surg 2023 May 1;34(3):849-854. Epub 2023 Mar 22 doi: 10.1097/SCS.0000000000009261. PMID: 36944600Free PMC Article
Surgically assisted maxillary expansion imparts three-dimensional nasal change.
Metzler P, Geiger EJ, Chang CC, Steinbacher DM
J Oral Maxillofac Surg 2014 Oct;72(10):2005-14. Epub 2014 Mar 13 doi: 10.1016/j.joms.2014.03.004. PMID: 24768418
Role of the sphenoidal process of the septal cartilage in the development of septal deviation.
Kim J, Kim SW, Kim SW, Cho JH, Park YJ
Otolaryngol Head Neck Surg 2012 Jan;146(1):151-5. Epub 2011 Oct 10 doi: 10.1177/0194599811425000. PMID: 21987650

Diagnosis

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review.
Jiang H, Yang X, Guo Y
Ear Nose Throat J 2024 Apr;103(4):NP226-NP228. Epub 2021 Oct 12 doi: 10.1177/01455613211051662. PMID: 34636258
Variants of the hyoid-larynx complex, with implications for forensic science and consequence for the diagnosis of Eagle's syndrome.
de Bakker BS, de Bakker HM, Soerdjbalie-Maikoe V, Dikkers FG
Sci Rep 2019 Nov 4;9(1):15950. doi: 10.1038/s41598-019-52476-z. PMID: 31685955Free PMC Article
Idiopathic acquired ectopic auricular ossification: a case report and review of the literature.
Chang KH, Kim DK, Kim JH, Park YS
Ear Nose Throat J 2011 Sep;90(9):424-7. doi: 10.1177/014556131109000908. PMID: 21938701
Congenital frontonasal masses: developmental anatomy, malformations, and MR imaging.
Hedlund G
Pediatr Radiol 2006 Jul;36(7):647-62; quiz 726-7. Epub 2006 Mar 11 doi: 10.1007/s00247-005-0100-3. PMID: 16532348
Achondrogenesis: case report and review of the literature.
Xanthakos UF, Rejent MM
J Pediatr 1973 Apr;82(4):658-63. doi: 10.1016/s0022-3476(73)80592-x. PMID: 4633363

Therapy

Use of hyaluronic acid matrix in dorsal augmentation rhinoplasty.
Erisgin Z, Hizli O, Yildirim G, Sivrikaya C, Sarisoy AB, Avci Y, Ozcan KM
Biotech Histochem 2023 Nov;98(8):561-566. Epub 2023 Aug 30 doi: 10.1080/10520295.2023.2248889. PMID: 37646474
Role of the sphenoidal process of the septal cartilage in the development of septal deviation.
Kim J, Kim SW, Kim SW, Cho JH, Park YJ
Otolaryngol Head Neck Surg 2012 Jan;146(1):151-5. Epub 2011 Oct 10 doi: 10.1177/0194599811425000. PMID: 21987650
Infrared laser therapy after surgically assisted rapid palatal expansion to diminish pain and accelerate bone healing.
Abreu ME, Viegas VN, Pagnoncelli RM, de Lima EM, Farret AM, Kulczynski FZ, Farret MM
World J Orthod 2010 Fall;11(3):273-7. PMID: 20877738
Neo-ossification of the cricothyroid joint after elective cricothyroidotomy: a case report and discussion on the merits of this procedure.
Chang CY, Thomas JP
J Trauma 2008 Nov;65(5):1146-50. doi: 10.1097/01.ta.0000202547.92731.4f. PMID: 17554221

Prognosis

Prenatal findings in a fetus with X-linked recessive type of chondrodysplasia punctata (CDPX1): a case report with novel mutation.
He G, Yin Y, Zhao J, Wang X, Yang J, Chen X, Ding L, Bai Y
BMC Pediatr 2019 Jul 23;19(1):250. doi: 10.1186/s12887-019-1629-x. PMID: 31337364Free PMC Article
Surgically assisted maxillary expansion imparts three-dimensional nasal change.
Metzler P, Geiger EJ, Chang CC, Steinbacher DM
J Oral Maxillofac Surg 2014 Oct;72(10):2005-14. Epub 2014 Mar 13 doi: 10.1016/j.joms.2014.03.004. PMID: 24768418
Pharyngeal airway changes associated with maxillary distraction osteogenesis in adult cleft lip and palate patients.
Aksu M, Taner T, Sahin-Veske P, Kocadereli I, Konas E, Mavili ME
J Oral Maxillofac Surg 2012 Feb;70(2):e133-40. doi: 10.1016/j.joms.2011.10.009. PMID: 22260915
Role of the sphenoidal process of the septal cartilage in the development of septal deviation.
Kim J, Kim SW, Kim SW, Cho JH, Park YJ
Otolaryngol Head Neck Surg 2012 Jan;146(1):151-5. Epub 2011 Oct 10 doi: 10.1177/0194599811425000. PMID: 21987650
Frontal sinus fractures: principles of treatment and long-term results after sinus obliteration with the use of lyophilized cartilage.
Sailer HF, Grätz KW, Kalavrezos ND
J Craniomaxillofac Surg 1998 Aug;26(4):235-42. doi: 10.1016/s1010-5182(98)80019-x. PMID: 9777502

Clinical prediction guides

Use of hyaluronic acid matrix in dorsal augmentation rhinoplasty.
Erisgin Z, Hizli O, Yildirim G, Sivrikaya C, Sarisoy AB, Avci Y, Ozcan KM
Biotech Histochem 2023 Nov;98(8):561-566. Epub 2023 Aug 30 doi: 10.1080/10520295.2023.2248889. PMID: 37646474
Nasal capsule ossification: A histological study using human foetuses to find an association between the foetus and adult morphologies of the nasal wall.
Yamamoto M, Hayashi S, Honkura Y, Hirano-Kawamoto A, Katori Y, Murakami G, Rodríguez-Vázquez JF, Abe S
J Anat 2023 Sep;243(3):517-533. Epub 2023 Mar 30 doi: 10.1111/joa.13867. PMID: 36998216Free PMC Article
The distribution patterns of COMP and matrilin-3 in septal, alar and triangular cartilages of the human nose.
Wiggenhauser PS, Schwarz S, Rotter N
Histochem Cell Biol 2018 Sep;150(3):291-300. Epub 2018 May 2 doi: 10.1007/s00418-018-1672-y. PMID: 29721643
Surgically assisted maxillary expansion imparts three-dimensional nasal change.
Metzler P, Geiger EJ, Chang CC, Steinbacher DM
J Oral Maxillofac Surg 2014 Oct;72(10):2005-14. Epub 2014 Mar 13 doi: 10.1016/j.joms.2014.03.004. PMID: 24768418
Morquio's disease and the hearing organ.
Kelemen G
ORL J Otorhinolaryngol Relat Spec 1977;39(4):233-40. doi: 10.1159/000275362. PMID: 415282

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