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Abnormality of the nose

MedGen UID:
539457
•Concept ID:
C0265736
•
Congenital Abnormality
Synonyms: Anomaly of the nose; Congenital anomaly of nose; Congenital deformity of nose; Congenital malformation of nose; Congenital nasal deformity; Deformity of the nose; Malformation of the nose; Nasal abnormality; Nasal anomaly; Nasal deformity; Nasal malformation
SNOMED CT: Congenital deformity of nose (72089000); Congenital malformation of nose (72089000); Congenital anomaly of nose (128274005); Congenital nasal deformity (72089000)
 
HPO: HP:0000366

Definition

An abnormality of the nose. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the nose

Conditions with this feature

Holoprosencephaly 3
MedGen UID:
327125
•Concept ID:
C1840529
•
Disease or Syndrome
Any holoprosencephaly in which the cause of the disease is a mutation in the SHH gene.
See: Condition Record
Holoprosencephaly 3

Professional guidelines

PubMed

The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Clinical Practice Guideline: Nosebleed (Epistaxis).
Tunkel DE, Anne S, Payne SC, Ishman SL, Rosenfeld RM, Abramson PJ, Alikhaani JD, Benoit MM, Bercovitz RS, Brown MD, Chernobilsky B, Feldstein DA, Hackell JM, Holbrook EH, Holdsworth SM, Lin KW, Lind MM, Poetker DM, Riley CA, Schneider JS, Seidman MD, Vadlamudi V, Valdez TA, Nnacheta LC, Monjur TM
Otolaryngol Head Neck Surg 2020 Jan;162(1_suppl):S1-S38. doi: 10.1177/0194599819890327. PMID: 31910111
Multiorgan involvement and management in children with Down syndrome.
Lagan N, Huggard D, Mc Grane F, Leahy TR, Franklin O, Roche E, Webb D, O' Marcaigh A, Cox D, El-Khuffash A, Greally P, Balfe J, Molloy EJ
Acta Paediatr 2020 Jun;109(6):1096-1111. Epub 2020 Jan 24 doi: 10.1111/apa.15153. PMID: 31899550

Recent clinical studies

Etiology

Balancing the Anteroposterior Diameters of the Nostril Lengths in Cleft Rhinoplasty.
Çerçi Özkan A, Bilgili AM, Kozanoğlu E
Aesthetic Plast Surg 2023 Aug;47(4):1513-1524. Epub 2022 Nov 2 doi: 10.1007/s00266-022-03153-6. PMID: 36323963
Challenging Rhinoplasty for the Cleft Lip and Palate Patient.
Cuzalina A, Tolomeo PG
Oral Maxillofac Surg Clin North Am 2021 Feb;33(1):143-159. doi: 10.1016/j.coms.2020.09.012. PMID: 33246546
Ultrasound screening: Status of markers and efficacy of screening for structural abnormalities.
Rao R, Platt LD
Semin Perinatol 2016 Feb;40(1):67-78. Epub 2016 Jan 8 doi: 10.1053/j.semperi.2015.11.009. PMID: 26777687
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Proboscis lateralis.
Lelli GJ Jr, Maher EA, Milite JP, Dyleski R
Ophthalmic Plast Reconstr Surg 2008 Nov-Dec;24(6):499-501. doi: 10.1097/IOP.0b013e31818b6e57. PMID: 19033859

Diagnosis

Neonatal nasal obstruction.
Alvo A, Villarroel G, Sedano C
Eur Arch Otorhinolaryngol 2021 Oct;278(10):3605-3611. Epub 2021 Jan 3 doi: 10.1007/s00405-020-06546-y. PMID: 33388986
Proboscis lateralis.
Martin S, Hogan E, Sorenson EP, Cohen-Gadol AA, Tubbs RS, Loukas M
Childs Nerv Syst 2013 Jun;29(6):885-91. Epub 2013 Jan 25 doi: 10.1007/s00381-012-1989-0. PMID: 23354442
Binder syndrome.
Chummun S, McLean NR, Nugent M, Anderson PJ, David DJ
J Craniofac Surg 2012 Jul;23(4):986-90. doi: 10.1097/SCS.0b013e31824e2683. PMID: 22777437
Binder's syndrome.
Jain U, Thakur G, Kallury A
BMJ Case Rep 2011 Oct 11;2011 doi: 10.1136/bcr.08.2011.4665. PMID: 22675013Free PMC Article
Nasal encephaloceles.
Hoving EW
Childs Nerv Syst 2000 Nov;16(10-11):702-6. doi: 10.1007/s003810000339. PMID: 11151720

Therapy

Correction of Short Nose.
Jung DH, Jin SG, Hyun SM
Facial Plast Surg Clin North Am 2018 Aug;26(3):377-388. Epub 2018 Jun 7 doi: 10.1016/j.fsc.2018.03.011. PMID: 30005793
Blowout fractures - clinic, imaging and applied anatomy of the orbit.
Felding UNA
Dan Med J 2018 Mar;65(3) PMID: 29510812
Spreader Grafts in Functional Rhinoplasty.
Kim L, Papel ID
Facial Plast Surg 2016 Feb;32(1):29-35. Epub 2016 Feb 10 doi: 10.1055/s-0035-1570127. PMID: 26862961
The importance of the nasal septum in the deviated nose.
Sykes JM, Kim JE, Shaye D, Boccieri A
Facial Plast Surg 2011 Oct;27(5):413-21. Epub 2011 Oct 25 doi: 10.1055/s-0031-1288928. PMID: 22028006
The role of the nose in snoring and obstructive sleep apnoea: an update.
Georgalas C
Eur Arch Otorhinolaryngol 2011 Sep;268(9):1365-73. Epub 2011 Feb 22 doi: 10.1007/s00405-010-1469-7. PMID: 21340561Free PMC Article

Prognosis

Pyriform aperture enlargement in all aspects.
Esen E, Bayar Muluk N, Altintoprak N, Ipci K, Cingi C
J Laryngol Otol 2017 Jun;131(6):476-479. Epub 2017 Feb 27 doi: 10.1017/S0022215117000391. PMID: 28238296
Ultrasound screening: Status of markers and efficacy of screening for structural abnormalities.
Rao R, Platt LD
Semin Perinatol 2016 Feb;40(1):67-78. Epub 2016 Jan 8 doi: 10.1053/j.semperi.2015.11.009. PMID: 26777687
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Proboscis lateralis.
Lelli GJ Jr, Maher EA, Milite JP, Dyleski R
Ophthalmic Plast Reconstr Surg 2008 Nov-Dec;24(6):499-501. doi: 10.1097/IOP.0b013e31818b6e57. PMID: 19033859
Nasal encephaloceles.
Hoving EW
Childs Nerv Syst 2000 Nov;16(10-11):702-6. doi: 10.1007/s003810000339. PMID: 11151720

Clinical prediction guides

Lip-Shortening Surgery.
Gatti JE
Plast Reconstr Surg 2023 Oct 1;152(4):765-772. Epub 2023 Mar 7 doi: 10.1097/PRS.0000000000010361. PMID: 36877617
What Is the Burden of Care of Nasoalveolar Molding?
Alfonso AR, Ramly EP, Kantar RS, Wang MM, Eisemann BS, Staffenberg DA, Shetye PR, Flores RL
Cleft Palate Craniofac J 2020 Sep;57(9):1078-1092. Epub 2020 Jun 5 doi: 10.1177/1055665620929224. PMID: 32500737
Does DNA Methylation Matter in FSHD?
Salsi V, Magdinier F, Tupler R
Genes (Basel) 2020 Feb 28;11(3) doi: 10.3390/genes11030258. PMID: 32121044Free PMC Article
Pediatric septorhinoplasty.
Funamura JL, Sykes JM
Facial Plast Surg Clin North Am 2014 Nov;22(4):503-8. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.005. PMID: 25444724
The crooked nose.
Boccieri A
Acta Otorhinolaryngol Ital 2013 Jun;33(3):163-8. PMID: 23853411Free PMC Article

Recent systematic reviews

Neuroradiological Basis of COVID-19 Olfactory Dysfunction: A Systematic Review and Meta-Analysis.
Tan CJ, Tan BKJ, Tan XY, Liu HT, Teo CB, See A, Xu S, Toh ST, Kheok SW, Charn TC, Teo NWY
Laryngoscope 2022 Jun;132(6):1260-1274. Epub 2022 Mar 22 doi: 10.1002/lary.30078. PMID: 35318656Free PMC Article
Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review.
Groff D, Sun A, Ssentongo AE, Ba DM, Parsons N, Poudel GR, Lekoubou A, Oh JS, Ericson JE, Ssentongo P, Chinchilli VM
JAMA Netw Open 2021 Oct 1;4(10):e2128568. doi: 10.1001/jamanetworkopen.2021.28568. PMID: 34643720Free PMC Article
Acute otitis media and antibiotics - a systematic review.
Holm NH, Rusan M, Ovesen T
Dan Med J 2020 Oct 29;67(11) PMID: 33215607
First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening.
Alldred SK, Takwoingi Y, Guo B, Pennant M, Deeks JJ, Neilson JP, Alfirevic Z
Cochrane Database Syst Rev 2017 Mar 15;3(3):CD012600. doi: 10.1002/14651858.CD012600. PMID: 28295158Free PMC Article
Regenerative medicine in otorhinolaryngology.
Wormald JC, Fishman JM, Juniat S, Tolley N, Birchall MA
J Laryngol Otol 2015 Aug;129(8):732-9. Epub 2015 Jun 24 doi: 10.1017/S0022215115001577. PMID: 26104952

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