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Childhood-onset truncal obesity

MedGen UID:
348475
Concept ID:
C1859846
Finding
Synonyms: Truncal obesity (onset in childhood); Truncal obesity apparent in childhood
 
HPO: HP:0008915

Definition

Truncal obesity with onset during childhood, defined as between 2 and 10 years of age. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood-onset truncal obesity

Conditions with this feature

Cohen syndrome
MedGen UID:
78539
Concept ID:
C0265223
Congenital Abnormality
Cohen syndrome is characterized by failure to thrive in infancy and childhood; truncal obesity in the teen years; early-onset hypotonia and developmental delays; microcephaly developing during the first year of life; moderate to profound psychomotor retardation; progressive retinochoroidal dystrophy and high myopia; neutropenia in many with recurrent infections and aphthous ulcers in some; a cheerful disposition; joint hypermobility; and characteristic facial features.
MORM syndrome
MedGen UID:
341851
Concept ID:
C1857802
Disease or Syndrome
Impaired intellectual development, truncal obesity, retinal dystrophy, and micropenis syndrome (MORMS) is an autosomal recessive disorder characterized by these findings (Hampshire et al., 2006).

Recent clinical studies

Diagnosis

Rohanizadegan M, Siddharath A, Retterer K, Hung C, Bodamer O
Cold Spring Harb Mol Case Stud 2020 Apr;6(2) Epub 2020 Apr 1 doi: 10.1101/mcs.a004846. PMID: 31969346Free PMC Article

Prognosis

Rohanizadegan M, Siddharath A, Retterer K, Hung C, Bodamer O
Cold Spring Harb Mol Case Stud 2020 Apr;6(2) Epub 2020 Apr 1 doi: 10.1101/mcs.a004846. PMID: 31969346Free PMC Article

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