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Presenile dementia, Kraepelin type

MedGen UID:
356847
•Concept ID:
C1867772
•
Disease or Syndrome
Synonyms: Catatonia of Kraepelin; Kraepelin disease
 
Monarch Initiative: MONDO:0008307
OMIM®: 176600

Clinical features

From HPO
Dementia
MedGen UID:
99229
•Concept ID:
C0497327
•
Mental or Behavioral Dysfunction
A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.
See: Feature record | Search on this feature
  • Abnormality of the nervous system

Recent clinical studies

Etiology

FDG-PET scans in patients with Kraepelinian and non-Kraepelinian schizophrenia.
Bralet MC, Buchsbaum MS, DeCastro A, Shihabuddin L, Mitelman SA
Eur Arch Psychiatry Clin Neurosci 2016 Sep;266(6):481-94. Epub 2015 Sep 14 doi: 10.1007/s00406-015-0633-x. PMID: 26370275
Increased advanced glycation end-products (AGEs) assessed by skin autofluorescence in schizophrenia.
Kouidrat Y, Amad A, Desailloud R, Diouf M, Fertout E, Scoury D, Lalau JD, Loas G
J Psychiatr Res 2013 Aug;47(8):1044-8. Epub 2013 Apr 21 doi: 10.1016/j.jpsychires.2013.03.016. PMID: 23615188

Diagnosis

Kraepelin's description of chronic mania: a clinical picture that meets the behavioral variant frontotemporal dementia phenotype.
Gambogi LB, Guimarães HC, Daker MV, de Souza LC, Caramelli P
Arq Neuropsiquiatr 2016 Sep;74(9):775-777. doi: 10.1590/0004-282X20160111. PMID: 27706428
Increased advanced glycation end-products (AGEs) assessed by skin autofluorescence in schizophrenia.
Kouidrat Y, Amad A, Desailloud R, Diouf M, Fertout E, Scoury D, Lalau JD, Loas G
J Psychiatr Res 2013 Aug;47(8):1044-8. Epub 2013 Apr 21 doi: 10.1016/j.jpsychires.2013.03.016. PMID: 23615188

Prognosis

FDG-PET scans in patients with Kraepelinian and non-Kraepelinian schizophrenia.
Bralet MC, Buchsbaum MS, DeCastro A, Shihabuddin L, Mitelman SA
Eur Arch Psychiatry Clin Neurosci 2016 Sep;266(6):481-94. Epub 2015 Sep 14 doi: 10.1007/s00406-015-0633-x. PMID: 26370275

Supplemental Content

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    Clinical resources

    Reviews

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    • MeSH
      Related Medical Subject Headings
    • OMIM
      Related records in OMIM
    • PubMed (OMIM)
      Related literature resources in PubMed

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