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Hodgkin Disease, Lymphocyte Depletion, Diffuse Fibrosis

MedGen UID:
361495
•Concept ID:
C1881058
•
Neoplastic Process
Synonym: Hodgkin's Disease, Lymphocyte Depletion, Diffuse Fibrosis

Definition

A lymphocyte depleted Hodgkin lymphoma characterized by the presence of diffuse fibrosis and a few Hodgkin and Reed-Sternberg cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHodgkin Disease, Lymphocyte Depletion, Diffuse Fibrosis

Recent clinical studies

Etiology

Splenic injury caused by therapeutic irradiation.
Dailey MO, Coleman CN, Fajardo LF
Am J Surg Pathol 1981 Jun;5(4):325-31. doi: 10.1097/00000478-198106000-00002. PMID: 7270781
Features and prognosis of chemotherapy-treated Hodgkin's disease with initial bone marrow involvement.
Auclerc G, Auclerc MF, Weil M, Andrieu JM, Jacquillat C, Bernard J
Cancer Chemother Pharmacol 1979;2(3):189-96. doi: 10.1007/BF00258294. PMID: 455574

Diagnosis

Epstein Barr virus-associated lymphoma in HIV-infected children.
Preciado MV, Fallo A, Chabay P, Calcagno L, De Matteo E
Pathol Res Pract 2002;198(5):327-32. doi: 10.1078/0344-0338-5710262. PMID: 12092768
EBV-associated Hodgkin's disease in an HIV-infected child presenting with a hemophagocytic syndrome.
Preciado MV, De Matteo E, Fallo A, Chabay P, Drelichman G, Grinstein S
Leuk Lymphoma 2001 Jun;42(1-2):231-4. doi: 10.3109/10428190109097696. PMID: 11699213
Lymphocyte-depletion Hodgkin's disease. Histopathologic diagnosis of marrow involvement.
Kinney MC, Greer JP, Stein RS, Collins RD, Cousar JB
Am J Surg Pathol 1986 Mar;10(3):219-26. PMID: 3953942
Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079
Hodgkin's disease with predominant infradiaphragmatic involvement and massive invasion of the bone marrow. A necropsic study of nine cases.
Sobrinho-Simões M, Paiva ME, Gonçalves V, Saldanha C, Vaz Saleiro J, Serrão D
Cancer 1983 Nov 15;52(10):1927-32. doi: 10.1002/1097-0142(19831115)52:10<1927::aid-cncr2820521025>3.0.co;2-0. PMID: 6627207

Therapy

Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079
Features and prognosis of chemotherapy-treated Hodgkin's disease with initial bone marrow involvement.
Auclerc G, Auclerc MF, Weil M, Andrieu JM, Jacquillat C, Bernard J
Cancer Chemother Pharmacol 1979;2(3):189-96. doi: 10.1007/BF00258294. PMID: 455574

Prognosis

EBV-associated Hodgkin's disease in an HIV-infected child presenting with a hemophagocytic syndrome.
Preciado MV, De Matteo E, Fallo A, Chabay P, Drelichman G, Grinstein S
Leuk Lymphoma 2001 Jun;42(1-2):231-4. doi: 10.3109/10428190109097696. PMID: 11699213
Bone marrow biopsy (BMB). III. Bone marrow biopsy in Hodgkin's disease (HD).
Macavei I, Galatâr N
Morphol Embryol (Bucur) 1990 Jan-Mar;36(1):25-32. PMID: 2149408
Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079
Splenic injury caused by therapeutic irradiation.
Dailey MO, Coleman CN, Fajardo LF
Am J Surg Pathol 1981 Jun;5(4):325-31. doi: 10.1097/00000478-198106000-00002. PMID: 7270781
Features and prognosis of chemotherapy-treated Hodgkin's disease with initial bone marrow involvement.
Auclerc G, Auclerc MF, Weil M, Andrieu JM, Jacquillat C, Bernard J
Cancer Chemother Pharmacol 1979;2(3):189-96. doi: 10.1007/BF00258294. PMID: 455574

Clinical prediction guides

Features and prognosis of chemotherapy-treated Hodgkin's disease with initial bone marrow involvement.
Auclerc G, Auclerc MF, Weil M, Andrieu JM, Jacquillat C, Bernard J
Cancer Chemother Pharmacol 1979;2(3):189-96. doi: 10.1007/BF00258294. PMID: 455574

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