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Hodgkin Disease, Lymphocyte Depletion, Reticular

MedGen UID:
361496
•Concept ID:
C1881059
•
Neoplastic Process
Synonym: Hodgkin's Disease, Lymphocyte Depletion, Reticular

Definition

A lymphocyte depleted Hodgkin lymphoma characterized by the presence of reticular fibrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHodgkin Disease, Lymphocyte Depletion, Reticular

Recent clinical studies

Etiology

Lymphocyte depleted Hodgkin lymphoma: an evaluation with immunophenotyping and genetic analysis.
Slack GW, Ferry JA, Hasserjian RP, Sohani AR, Longtine JA, Harris NL, Zukerberg LR
Leuk Lymphoma 2009 Jun;50(6):937-43. doi: 10.1080/10428190902930488. PMID: 19455461

Diagnosis

Lymphocyte depleted Hodgkin lymphoma: an evaluation with immunophenotyping and genetic analysis.
Slack GW, Ferry JA, Hasserjian RP, Sohani AR, Longtine JA, Harris NL, Zukerberg LR
Leuk Lymphoma 2009 Jun;50(6):937-43. doi: 10.1080/10428190902930488. PMID: 19455461
Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation?
Pinkus GS, Pinkus JL, Langhoff E, Matsumura F, Yamashiro S, Mosialos G, Said JW
Am J Pathol 1997 Feb;150(2):543-62. PMID: 9033270Free PMC Article
Lymphocyte-depletion Hodgkin's disease. Histopathologic diagnosis of marrow involvement.
Kinney MC, Greer JP, Stein RS, Collins RD, Cousar JB
Am J Surg Pathol 1986 Mar;10(3):219-26. PMID: 3953942
Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079
Hodgkin's disease with predominant infradiaphragmatic involvement and massive invasion of the bone marrow. A necropsic study of nine cases.
Sobrinho-Simões M, Paiva ME, Gonçalves V, Saldanha C, Vaz Saleiro J, Serrão D
Cancer 1983 Nov 15;52(10):1927-32. doi: 10.1002/1097-0142(19831115)52:10<1927::aid-cncr2820521025>3.0.co;2-0. PMID: 6627207

Therapy

Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079

Prognosis

Lymphocyte-depleted Hodgkin's disease. Clinicopathologic review of 25 patients.
Greer JP, Kinney MC, Cousar JB, Flexner JM, Dupont WD, Graber SE, Greco FA, Collins RD, Stein RS
Am J Med 1986 Aug;81(2):208-14. doi: 10.1016/0002-9343(86)90253-6. PMID: 3740079

Clinical prediction guides

Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation?
Pinkus GS, Pinkus JL, Langhoff E, Matsumura F, Yamashiro S, Mosialos G, Said JW
Am J Pathol 1997 Feb;150(2):543-62. PMID: 9033270Free PMC Article
Tenascin in reactive lymph nodes and in malignant lymphomas.
Soini Y, Alavaikko M, Lehto VP, Virtanen I
Pathol Res Pract 1992 Dec;188(8):1078-82. doi: 10.1016/S0344-0338(11)81254-9. PMID: 1284450
Distribution of fibrous long-spacing fibers in normal and pathological lymph nodes.
Nakanishi I, Masuda S, Kitamura T, Moriizumi T, Kajikawa K
Acta Pathol Jpn 1981 Sep;31(5):733-45. doi: 10.1111/j.1440-1827.1981.tb02799.x. PMID: 7304166

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