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Utricle-Associated Mucosal Gland Hyperplasia

MedGen UID:
362943
•Concept ID:
C1883513
•
Pathologic Function

Definition

A benign microacinar proliferation occurring exclusively in the area of the utricle. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUtricle-Associated Mucosal Gland Hyperplasia

Professional guidelines

PubMed

Genotype-Phenotype Correlation in Indian Patients with MEN2-Associated Pheochromocytoma and Comparison of Clinico-Pathological Attributes with Apparently Sporadic Adrenal Pheochromocytoma.
Rajan S, Zaidi G, Agarwal G, Mishra A, Agarwal A, Mishra SK, Bhatia E
World J Surg 2016 Mar;40(3):690-6. doi: 10.1007/s00268-015-3255-6. PMID: 26438242
Corticosteroid treatment regulates mucosal remodeling in chronic rhinosinusitis with nasal polyps.
de Borja Callejas F, Martínez-Antón A, Picado C, Alobid I, Pujols L, Valero A, Roca-Ferrer J, Mullol J
Laryngoscope 2015 May;125(5):E158-67. Epub 2015 Jan 13 doi: 10.1002/lary.25147. PMID: 25641502
Low grade B cell mucosa associated lymphoid tissue lymphoma of the stomach: clinical and endoscopic features, treatment, and outcome.
Blazquez M, Haioun C, Chaumette MT, Gaulard P, Reyes F, Soulé JC, Delchier JC
Gut 1992 Dec;33(12):1621-5. doi: 10.1136/gut.33.12.1621. PMID: 1487163Free PMC Article

Recent clinical studies

Etiology

Clinicopathologic features of non-type 1/2 gastric neuroendocrine tumors and their associated mucosal changes.
Logan K, Shi C
Am J Clin Pathol 2023 Aug 1;160(2):130-136. doi: 10.1093/ajcp/aqad021. PMID: 37022112
Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond.
Goldenring JR, Mills JC
Gastroenterology 2022 Feb;162(2):415-430. Epub 2021 Oct 30 doi: 10.1053/j.gastro.2021.10.036. PMID: 34728185Free PMC Article
Proton Pump Inhibitor-Related Gastric Mucosal Changes.
Kim GH
Gut Liver 2021 Sep 15;15(5):646-652. doi: 10.5009/gnl20036. PMID: 32327613Free PMC Article
Esophageal submucosal gland duct adenoma: a clinicopathological and immunohistochemical study with a review of the literature.
Nie L, Wu HY, Shen YH, Fan XS, Sun Q, Huang Q, Chen J
Dis Esophagus 2016 Nov;29(8):1048-1053. Epub 2015 Nov 6 doi: 10.1111/dote.12442. PMID: 26542981
Activation and hyperplasia of gastrin and enterochromaffin-like cells in the stomach.
Håkanson R, Böttcher G, Sundler F, Vallgren S
Digestion 1986;35 Suppl 1:23-41. doi: 10.1159/000199380. PMID: 3539678

Diagnosis

Rat Experimental Autoimmune Gastritis Model.
Beduleva L, Fomina K, Sidorov A, Terentiev A, Ivanov P, Menshikov I
Immunol Invest 2023 Nov;52(8):1023-1038. Epub 2023 Nov 24 doi: 10.1080/08820139.2023.2283103. PMID: 37962068
Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond.
Goldenring JR, Mills JC
Gastroenterology 2022 Feb;162(2):415-430. Epub 2021 Oct 30 doi: 10.1053/j.gastro.2021.10.036. PMID: 34728185Free PMC Article
International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
Prostate immunology: A challenging puzzle.
Silva JAF, Calmasini F, Siqueira-Berti A, Moraes-Vieira PMM, Quintar A, Carvalho HF
J Reprod Immunol 2020 Nov;142:103190. Epub 2020 Aug 18 doi: 10.1016/j.jri.2020.103190. PMID: 32853844
Rare syndromes.
Jabbour SA, Davidovici BB, Wolf R
Clin Dermatol 2006 Jul-Aug;24(4):299-316. doi: 10.1016/j.clindermatol.2006.04.005. PMID: 16828412

Therapy

International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
Proton Pump Inhibitor-Related Gastric Mucosal Changes.
Kim GH
Gut Liver 2021 Sep 15;15(5):646-652. doi: 10.5009/gnl20036. PMID: 32327613Free PMC Article
Mast Cell-Mediated Orchestration of the Immune Responses in Human Allergic Asthma: Current Insights.
Elieh Ali Komi D, Bjermer L
Clin Rev Allergy Immunol 2019 Apr;56(2):234-247. doi: 10.1007/s12016-018-8720-1. PMID: 30506113
Long-term proton pump inhibitor use and gastrointestinal cancer.
Graham DY, Genta RM
Curr Gastroenterol Rep 2008 Dec;10(6):543-7. doi: 10.1007/s11894-008-0100-1. PMID: 19006608Free PMC Article
The consequences of hypergastrinemia.
Creutzfeldt W
Yale J Biol Med 1994 May-Aug;67(3-4):181-94. PMID: 7502528Free PMC Article

Prognosis

Pathology and Clinical Relevance of Gastric Epithelial Dysplasia.
Ushiku T, Lauwers GY
Gastroenterol Clin North Am 2024 Mar;53(1):39-55. doi: 10.1016/j.gtc.2023.11.003. PMID: 38280750
Mesenteric Arteriovenous Dysplasia/Vasculopathy Is Distinct From Fibromuscular Dysplasia.
Patil DT, Kissiedu J, Rodriguez ER, Downs-Kelly E, Liu X, Rybicki LA, Tan CD
Am J Surg Pathol 2016 Oct;40(10):1316-25. doi: 10.1097/PAS.0000000000000710. PMID: 27487739
Incidence and risk factor of fundic gland polyp and hyperplastic polyp in long-term proton pump inhibitor therapy: a prospective study in Japan.
Hongo M, Fujimoto K; Gastric Polyps Study Group
J Gastroenterol 2010 Jun;45(6):618-24. Epub 2010 Feb 23 doi: 10.1007/s00535-010-0207-7. PMID: 20177714
Pathology of colorectal cancer.
Ponz de Leon M, Di Gregorio C
Dig Liver Dis 2001 May;33(4):372-88. doi: 10.1016/s1590-8658(01)80095-5. PMID: 11432519
Hyperplastic gastropathy. Clinicopathologic correlation.
Komorowski RA, Caya JG
Am J Surg Pathol 1991 Jun;15(6):577-85. doi: 10.1097/00000478-199106000-00006. PMID: 2031530

Clinical prediction guides

Pathology and Clinical Relevance of Gastric Epithelial Dysplasia.
Ushiku T, Lauwers GY
Gastroenterol Clin North Am 2024 Mar;53(1):39-55. doi: 10.1016/j.gtc.2023.11.003. PMID: 38280750
International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
Mast Cell-Mediated Orchestration of the Immune Responses in Human Allergic Asthma: Current Insights.
Elieh Ali Komi D, Bjermer L
Clin Rev Allergy Immunol 2019 Apr;56(2):234-247. doi: 10.1007/s12016-018-8720-1. PMID: 30506113
Airway remodeling in asthma.
Sumi Y, Hamid Q
Allergol Int 2007 Dec;56(4):341-8. Epub 2007 Nov 1 doi: 10.2332/allergolint.R-07-153. PMID: 17965577
The consequences of hypergastrinemia.
Creutzfeldt W
Yale J Biol Med 1994 May-Aug;67(3-4):181-94. PMID: 7502528Free PMC Article

Recent systematic reviews

International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article

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