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Supranuclear palsy, progressive, 3(PSNP3)

MedGen UID:
370922
Concept ID:
C1970476
Disease or Syndrome
Synonym: PSNP3
 
Monarch Initiative: MONDO:0012576
OMIM®: 610898

Professional guidelines

PubMed

Coughlin DG, Litvan I
Expert Opin Investig Drugs 2022 Aug;31(8):813-823. Epub 2022 Jun 13 doi: 10.1080/13543784.2022.2087179. PMID: 35695010
Wu P, Zhao Y, Wu J, Brendel M, Lu J, Ge J, Bernhardt A, Li L, Alberts I, Katzdobler S, Yakushev I, Hong J, Xu Q, Sun Y, Liu F, Levin J, Höglinger GU, Bassetti C, Guan Y, Oertel WH, Weber W, Rominger A, Wang J, Zuo C, Shi K
J Nucl Med 2022 Nov;63(11):1741-1747. Epub 2022 Mar 3 doi: 10.2967/jnumed.121.263029. PMID: 35241481Free PMC Article
Minoshima S, Mosci K, Cross D, Thientunyakit T
Semin Nucl Med 2021 May;51(3):230-240. Epub 2021 Feb 2 doi: 10.1053/j.semnuclmed.2021.01.002. PMID: 33546814

Recent clinical studies

Etiology

Baiardi S, Quadalti C, Mammana A, Dellavalle S, Zenesini C, Sambati L, Pantieri R, Polischi B, Romano L, Suffritti M, Bentivenga GM, Randi V, Stanzani-Maserati M, Capellari S, Parchi P
Alzheimers Res Ther 2022 Oct 12;14(1):153. doi: 10.1186/s13195-022-01093-6. PMID: 36221099Free PMC Article
Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ, Höglinger GU
Acta Neuropathol 2020 Aug;140(2):99-119. Epub 2020 May 7 doi: 10.1007/s00401-020-02158-2. PMID: 32383020Free PMC Article
Jabbari E, Holland N, Chelban V, Jones PS, Lamb R, Rawlinson C, Guo T, Costantini AA, Tan MMX, Heslegrave AJ, Roncaroli F, Klein JC, Ansorge O, Allinson KSJ, Jaunmuktane Z, Holton JL, Revesz T, Warner TT, Lees AJ, Zetterberg H, Russell LL, Bocchetta M, Rohrer JD, Williams NM, Grosset DG, Burn DJ, Pavese N, Gerhard A, Kobylecki C, Leigh PN, Church A, Hu MTM, Woodside J, Houlden H, Rowe JB, Morris HR
JAMA Neurol 2020 Mar 1;77(3):377-387. doi: 10.1001/jamaneurol.2019.4347. PMID: 31860007Free PMC Article
Rabadia SV, Litvan I, Juncos J, Bordelon Y, Riley DE, Standaert D, Reich SG, Hall DA, Kluger B, Shprecher D, Marras C, Jankovic J; ENGENE PSP study
Parkinsonism Relat Disord 2019 Sep;66:166-170. Epub 2019 Aug 3 doi: 10.1016/j.parkreldis.2019.07.036. PMID: 31420308
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Diagnosis

Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature 2021 Oct;598(7880):359-363. Epub 2021 Sep 29 doi: 10.1038/s41586-021-03911-7. PMID: 34588692Free PMC Article
Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ, Höglinger GU
Acta Neuropathol 2020 Aug;140(2):99-119. Epub 2020 May 7 doi: 10.1007/s00401-020-02158-2. PMID: 32383020Free PMC Article
Jabbari E, Holland N, Chelban V, Jones PS, Lamb R, Rawlinson C, Guo T, Costantini AA, Tan MMX, Heslegrave AJ, Roncaroli F, Klein JC, Ansorge O, Allinson KSJ, Jaunmuktane Z, Holton JL, Revesz T, Warner TT, Lees AJ, Zetterberg H, Russell LL, Bocchetta M, Rohrer JD, Williams NM, Grosset DG, Burn DJ, Pavese N, Gerhard A, Kobylecki C, Leigh PN, Church A, Hu MTM, Woodside J, Houlden H, Rowe JB, Morris HR
JAMA Neurol 2020 Mar 1;77(3):377-387. doi: 10.1001/jamaneurol.2019.4347. PMID: 31860007Free PMC Article
Armstrong MJ
Curr Neurol Neurosci Rep 2018 Feb 17;18(3):12. doi: 10.1007/s11910-018-0819-5. PMID: 29455271
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Therapy

Lyons S, Trépel D, Lynch T, Walsh R, O'Dowd S
J Neurol 2023 Sep;270(9):4451-4465. Epub 2023 Jun 8 doi: 10.1007/s00415-023-11791-2. PMID: 37289323Free PMC Article
Logroscino G, Piccininni M, Graff C, Hardiman O, Ludolph AC, Moreno F, Otto M, Remes AM, Rowe JB, Seelaar H, Solje E, Stefanova E, Traykov L, Jelic V, Rydell MT, Pender N, Anderl-Straub S, Barandiaran M, Gabilondo A, Krüger J, Murley AG, Rittman T, van der Ende EL, van Swieten JC, Hartikainen P, Stojmenovic GM, Mehrabian S, Benussi L, Alberici A, Dell'Abate MT, Zecca C, Borroni B; FRONTIERS group
JAMA Neurol 2023 Mar 1;80(3):279-286. doi: 10.1001/jamaneurol.2022.5128. PMID: 36716024Free PMC Article
Höglinger GU, Litvan I, Mendonca N, Wang D, Zheng H, Rendenbach-Mueller B, Lon HK, Jin Z, Fisseha N, Budur K, Gold M, Ryman D, Florian H; Arise Investigators
Lancet Neurol 2021 Mar;20(3):182-192. doi: 10.1016/S1474-4422(20)30489-0. PMID: 33609476
Pîrşcoveanu DFV, Pirici I, Tudorică V, Bălşeanu TA, Albu VC, Bondari S, Bumbea AM, Pîrşcoveanu M
Rom J Morphol Embryol 2017;58(4):1141-1150. PMID: 29556602
Koros C, Stamelou M
Parkinsonism Relat Disord 2016 Jan;22 Suppl 1:S93-5. Epub 2015 Sep 25 doi: 10.1016/j.parkreldis.2015.09.033. PMID: 26459661

Prognosis

Shir D, Pham NTT, Botha H, Koga S, Kouri N, Ali F, Knopman DS, Petersen RC, Boeve BF, Kremers WK, Nguyen AT, Murray ME, Reichard RR, Dickson DW, Graff-Radford N, Josephs KA, Whitwell J, Graff-Radford J
Neurology 2023 Jul 18;101(3):e289-e299. Epub 2023 Jun 2 doi: 10.1212/WNL.0000000000207397. PMID: 37268436Free PMC Article
Sengupta U, Kayed R
Prog Neurobiol 2022 Jul;214:102270. Epub 2022 Apr 18 doi: 10.1016/j.pneurobio.2022.102270. PMID: 35447272
Naasan G, Shdo SM, Rodriguez EM, Spina S, Grinberg L, Lopez L, Karydas A, Seeley WW, Miller BL, Rankin KP
Brain 2021 Apr 12;144(3):999-1012. doi: 10.1093/brain/awaa413. PMID: 33501939Free PMC Article
Rabadia SV, Litvan I, Juncos J, Bordelon Y, Riley DE, Standaert D, Reich SG, Hall DA, Kluger B, Shprecher D, Marras C, Jankovic J; ENGENE PSP study
Parkinsonism Relat Disord 2019 Sep;66:166-170. Epub 2019 Aug 3 doi: 10.1016/j.parkreldis.2019.07.036. PMID: 31420308
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Clinical prediction guides

Shir D, Pham NTT, Botha H, Koga S, Kouri N, Ali F, Knopman DS, Petersen RC, Boeve BF, Kremers WK, Nguyen AT, Murray ME, Reichard RR, Dickson DW, Graff-Radford N, Josephs KA, Whitwell J, Graff-Radford J
Neurology 2023 Jul 18;101(3):e289-e299. Epub 2023 Jun 2 doi: 10.1212/WNL.0000000000207397. PMID: 37268436Free PMC Article
Sengupta U, Kayed R
Prog Neurobiol 2022 Jul;214:102270. Epub 2022 Apr 18 doi: 10.1016/j.pneurobio.2022.102270. PMID: 35447272
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature 2021 Oct;598(7880):359-363. Epub 2021 Sep 29 doi: 10.1038/s41586-021-03911-7. PMID: 34588692Free PMC Article
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article
Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD
Brain 2015 Sep;138(Pt 9):2732-49. Epub 2015 Jul 2 doi: 10.1093/brain/awv191. PMID: 26141491Free PMC Article

Recent systematic reviews

Lyons S, Trépel D, Lynch T, Walsh R, O'Dowd S
J Neurol 2023 Sep;270(9):4451-4465. Epub 2023 Jun 8 doi: 10.1007/s00415-023-11791-2. PMID: 37289323Free PMC Article
Ma X, Wang Y, Wang N, Zhang R
J Neurol 2022 Mar;269(3):1272-1281. Epub 2021 Jul 10 doi: 10.1007/s00415-021-10703-6. PMID: 34245345
Flavell J, Nestor PJ
J Geriatr Psychiatry Neurol 2022 May;35(3):280-292. Epub 2021 Feb 11 doi: 10.1177/0891988721993545. PMID: 33567955
Slade SC, Underwood M, McGinley JL, Morris ME
BMC Neurol 2019 Nov 29;19(1):305. doi: 10.1186/s12883-019-1539-4. PMID: 31783740Free PMC Article
Glasmacher SA, Leigh PN, Saha RA
J Neurol Neurosurg Psychiatry 2017 May;88(5):402-411. Epub 2017 Mar 1 doi: 10.1136/jnnp-2016-314956. PMID: 28250027

Supplemental Content

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    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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