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Supranuclear palsy, progressive, 3(PSNP3)

MedGen UID:
370922
Concept ID:
C1970476
Disease or Syndrome
Synonym: PSNP3
 
Monarch Initiative: MONDO:0012576
OMIM®: 610898

Professional guidelines

PubMed

Wu P, Zhao Y, Wu J, Brendel M, Lu J, Ge J, Bernhardt A, Li L, Alberts I, Katzdobler S, Yakushev I, Hong J, Xu Q, Sun Y, Liu F, Levin J, Höglinger GU, Bassetti C, Guan Y, Oertel WH, Weber W, Rominger A, Wang J, Zuo C, Shi K
J Nucl Med 2022 Nov;63(11):1741-1747. Epub 2022 Mar 3 doi: 10.2967/jnumed.121.263029. PMID: 35241481Free PMC Article
Minoshima S, Mosci K, Cross D, Thientunyakit T
Semin Nucl Med 2021 May;51(3):230-240. Epub 2021 Feb 2 doi: 10.1053/j.semnuclmed.2021.01.002. PMID: 33546814
Walker Z, Gandolfo F, Orini S, Garibotto V, Agosta F, Arbizu J, Bouwman F, Drzezga A, Nestor P, Boccardi M, Altomare D, Festari C, Nobili F; EANM-EAN Task Force for the recommendation of FDG PET for Dementing Neurodegenerative Disorders
Eur J Nucl Med Mol Imaging 2018 Jul;45(9):1534-1545. Epub 2018 May 19 doi: 10.1007/s00259-018-4031-2. PMID: 29779045Free PMC Article

Recent clinical studies

Etiology

Baiardi S, Quadalti C, Mammana A, Dellavalle S, Zenesini C, Sambati L, Pantieri R, Polischi B, Romano L, Suffritti M, Bentivenga GM, Randi V, Stanzani-Maserati M, Capellari S, Parchi P
Alzheimers Res Ther 2022 Oct 12;14(1):153. doi: 10.1186/s13195-022-01093-6. PMID: 36221099Free PMC Article
Artusi CA, Rinaldi D, Balestrino R, Lopiano L
Parkinsonism Relat Disord 2022 Mar;96:109-118. Epub 2022 Mar 9 doi: 10.1016/j.parkreldis.2022.03.002. PMID: 35288028
Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ, Höglinger GU
Acta Neuropathol 2020 Aug;140(2):99-119. Epub 2020 May 7 doi: 10.1007/s00401-020-02158-2. PMID: 32383020Free PMC Article
Jabbari E, Holland N, Chelban V, Jones PS, Lamb R, Rawlinson C, Guo T, Costantini AA, Tan MMX, Heslegrave AJ, Roncaroli F, Klein JC, Ansorge O, Allinson KSJ, Jaunmuktane Z, Holton JL, Revesz T, Warner TT, Lees AJ, Zetterberg H, Russell LL, Bocchetta M, Rohrer JD, Williams NM, Grosset DG, Burn DJ, Pavese N, Gerhard A, Kobylecki C, Leigh PN, Church A, Hu MTM, Woodside J, Houlden H, Rowe JB, Morris HR
JAMA Neurol 2020 Mar 1;77(3):377-387. doi: 10.1001/jamaneurol.2019.4347. PMID: 31860007Free PMC Article
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Diagnosis

Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature 2021 Oct;598(7880):359-363. Epub 2021 Sep 29 doi: 10.1038/s41586-021-03911-7. PMID: 34588692Free PMC Article
Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ, Höglinger GU
Acta Neuropathol 2020 Aug;140(2):99-119. Epub 2020 May 7 doi: 10.1007/s00401-020-02158-2. PMID: 32383020Free PMC Article
Jabbari E, Holland N, Chelban V, Jones PS, Lamb R, Rawlinson C, Guo T, Costantini AA, Tan MMX, Heslegrave AJ, Roncaroli F, Klein JC, Ansorge O, Allinson KSJ, Jaunmuktane Z, Holton JL, Revesz T, Warner TT, Lees AJ, Zetterberg H, Russell LL, Bocchetta M, Rohrer JD, Williams NM, Grosset DG, Burn DJ, Pavese N, Gerhard A, Kobylecki C, Leigh PN, Church A, Hu MTM, Woodside J, Houlden H, Rowe JB, Morris HR
JAMA Neurol 2020 Mar 1;77(3):377-387. doi: 10.1001/jamaneurol.2019.4347. PMID: 31860007Free PMC Article
Armstrong MJ
Curr Neurol Neurosci Rep 2018 Feb 17;18(3):12. doi: 10.1007/s11910-018-0819-5. PMID: 29455271
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Therapy

Gendron TF, Heckman MG, White LJ, Veire AM, Pedraza O, Burch AR, Bozoki AC, Dickerson BC, Domoto-Reilly K, Foroud T, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Huey ED, Hsiung GR, Irwin DJ, Kaufer DI, Leger GC, Litvan I, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Ritter A, Roberson ED, Rojas JC, Tartaglia MC, Wszolek ZK, Rosen H, Boeve BF, Boxer AL; ALLFTD consortium, Petrucelli L
Cell Rep Med 2022 Apr 19;3(4):100607. doi: 10.1016/j.xcrm.2022.100607. PMID: 35492244Free PMC Article
Artusi CA, Rinaldi D, Balestrino R, Lopiano L
Parkinsonism Relat Disord 2022 Mar;96:109-118. Epub 2022 Mar 9 doi: 10.1016/j.parkreldis.2022.03.002. PMID: 35288028
Intiso D, Bartolo M, Santamato A, Di Rienzo F
PM R 2018 Jun;10(6):636-645. Epub 2018 Jan 31 doi: 10.1016/j.pmrj.2017.12.011. PMID: 29366918
Pîrşcoveanu DFV, Pirici I, Tudorică V, Bălşeanu TA, Albu VC, Bondari S, Bumbea AM, Pîrşcoveanu M
Rom J Morphol Embryol 2017;58(4):1141-1150. PMID: 29556602
Koros C, Stamelou M
Parkinsonism Relat Disord 2016 Jan;22 Suppl 1:S93-5. Epub 2015 Sep 25 doi: 10.1016/j.parkreldis.2015.09.033. PMID: 26459661

Prognosis

Gendron TF, Heckman MG, White LJ, Veire AM, Pedraza O, Burch AR, Bozoki AC, Dickerson BC, Domoto-Reilly K, Foroud T, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Huey ED, Hsiung GR, Irwin DJ, Kaufer DI, Leger GC, Litvan I, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Ritter A, Roberson ED, Rojas JC, Tartaglia MC, Wszolek ZK, Rosen H, Boeve BF, Boxer AL; ALLFTD consortium, Petrucelli L
Cell Rep Med 2022 Apr 19;3(4):100607. doi: 10.1016/j.xcrm.2022.100607. PMID: 35492244Free PMC Article
Sengupta U, Kayed R
Prog Neurobiol 2022 Jul;214:102270. Epub 2022 Apr 18 doi: 10.1016/j.pneurobio.2022.102270. PMID: 35447272
Naasan G, Shdo SM, Rodriguez EM, Spina S, Grinberg L, Lopez L, Karydas A, Seeley WW, Miller BL, Rankin KP
Brain 2021 Apr 12;144(3):999-1012. doi: 10.1093/brain/awaa413. PMID: 33501939Free PMC Article
Walker Z, Gandolfo F, Orini S, Garibotto V, Agosta F, Arbizu J, Bouwman F, Drzezga A, Nestor P, Boccardi M, Altomare D, Festari C, Nobili F; EANM-EAN Task Force for the recommendation of FDG PET for Dementing Neurodegenerative Disorders
Eur J Nucl Med Mol Imaging 2018 Jul;45(9):1534-1545. Epub 2018 May 19 doi: 10.1007/s00259-018-4031-2. PMID: 29779045Free PMC Article
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article

Clinical prediction guides

Sengupta U, Kayed R
Prog Neurobiol 2022 Jul;214:102270. Epub 2022 Apr 18 doi: 10.1016/j.pneurobio.2022.102270. PMID: 35447272
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature 2021 Oct;598(7880):359-363. Epub 2021 Sep 29 doi: 10.1038/s41586-021-03911-7. PMID: 34588692Free PMC Article
Walker Z, Gandolfo F, Orini S, Garibotto V, Agosta F, Arbizu J, Bouwman F, Drzezga A, Nestor P, Boccardi M, Altomare D, Festari C, Nobili F; EANM-EAN Task Force for the recommendation of FDG PET for Dementing Neurodegenerative Disorders
Eur J Nucl Med Mol Imaging 2018 Jul;45(9):1534-1545. Epub 2018 May 19 doi: 10.1007/s00259-018-4031-2. PMID: 29779045Free PMC Article
Finger EC
Continuum (Minneap Minn) 2016 Apr;22(2 Dementia):464-89. doi: 10.1212/CON.0000000000000300. PMID: 27042904Free PMC Article
Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD
Brain 2015 Sep;138(Pt 9):2732-49. Epub 2015 Jul 2 doi: 10.1093/brain/awv191. PMID: 26141491Free PMC Article

Recent systematic reviews

Artusi CA, Rinaldi D, Balestrino R, Lopiano L
Parkinsonism Relat Disord 2022 Mar;96:109-118. Epub 2022 Mar 9 doi: 10.1016/j.parkreldis.2022.03.002. PMID: 35288028
Flavell J, Nestor PJ
J Geriatr Psychiatry Neurol 2022 May;35(3):280-292. Epub 2021 Feb 11 doi: 10.1177/0891988721993545. PMID: 33567955
Wittke C, Petkovic S, Dobricic V, Schaake S; MDS‐endorsed PSP Study Group, Respondek G, Weissbach A, Madoev H, Trinh J, Vollstedt EJ, Kuhnke N, Lohmann K, Dulovic Mahlow M, Marras C, König IR, Stamelou M, Bonifati V, Lill CM, Kasten M, Huppertz HJ, Höglinger G, Klein C
Mov Disord 2021 Jul;36(7):1499-1510. Epub 2021 Mar 19 doi: 10.1002/mds.28517. PMID: 34396589Free PMC Article
Slade SC, Underwood M, McGinley JL, Morris ME
BMC Neurol 2019 Nov 29;19(1):305. doi: 10.1186/s12883-019-1539-4. PMID: 31783740Free PMC Article
Glasmacher SA, Leigh PN, Saha RA
J Neurol Neurosurg Psychiatry 2017 May;88(5):402-411. Epub 2017 Mar 1 doi: 10.1136/jnnp-2016-314956. PMID: 28250027

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