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Diffuse large B-cell lymphoma of the central nervous system

MedGen UID:
378339
Concept ID:
C2026186
Neoplastic Process
Synonyms: Central Nervous System Diffuse Large B-Cell Lymphoma; central nervous system diffuse large B-cell lymphoma; Central Nervous System Primary Large B-Cell Lymphoma; CNS DLBCL; CNS Primary Large B-Cell Lymphoma; Diffuse large B-cell lymphoma of central nervous system; diffuse large B-cell lymphoma of central nervous system; diffuse large B-cell lymphoma of the central nervous system; DLBCL of the CNS; Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System; primary diffuse large B-cell lymphoma of the central nervous system; Primary Diffuse Large B-Cell Lymphoma of the CNS; Primary DLBCL of the CNS; primary DLBCL of the CNS; Primary Large B-Cell Lymphoma of the Central Nervous System; Primary Large B-Cell Lymphoma of the CNS
SNOMED CT: Diffuse large B-cell lymphoma of central nervous system (734066005)
Modes of inheritance:
 
Monarch Initiative: MONDO:0017596
Orphanet: ORPHA300849

Definition

A diffuse large B-cell lymphoma arising from the central nervous system. [from NCI]

Professional guidelines

PubMed

Isbell LK, Tschuch C, Doostkam S, Waldeck S, Andrieux G, Shoumariyeh K, Lenhard D, Schaefer HE, Reinacher PC, Bartsch I, Pantic M, Vinnakota JM, Kakkassery V, Schorb E, Scherer F, Frey AV, Boerries M, Illerhaus G, Duyster J, Schueler J, von Bubnoff N
Neuropathol Appl Neurobiol 2023 Apr;49(2):e12899. doi: 10.1111/nan.12899. PMID: 36879456
Liu B, Yan S, Li S, Zhang Q, Yang M, Yang L, Ma J, Li X
Pathol Res Pract 2022 Nov;239:154008. Epub 2022 Aug 23 doi: 10.1016/j.prp.2022.154008. PMID: 36183436
Schorb E, Fox CP, Kasenda B, Linton K, Martinez-Calle N, Calimeri T, Ninkovic S, Eyre TA, Cummin T, Smith J, Yallop D, De Marco B, Krampera M, Trefz S, Orsucci L, Fabbri A, Illerhaus G, Cwynarski K, Ferreri AJM
Br J Haematol 2020 Jun;189(5):879-887. Epub 2020 Jan 29 doi: 10.1111/bjh.16451. PMID: 31997308

Recent clinical studies

Etiology

Akhtar OS, Arshad S, Lian Q, Ahn KW, D'Souza A, Dhakal B, Mohan M, Pasquini M, Longo W, Shah NN, Fenske TS, Hamadani M
Transplant Cell Ther 2024 Dec;30(12):1191.e1-1191.e8. Epub 2024 Sep 18 doi: 10.1016/j.jtct.2024.09.015. PMID: 39303985
Guo S, Bai Q, Rohr J, Wang Y, Liu Y, Zeng K, Yu K, Zhang X, Wang Z
APMIS 2016 Dec;124(12):1054-1062. Epub 2016 Nov 2 doi: 10.1111/apm.12623. PMID: 27807891

Diagnosis

Odani K, Fujimoto M, Fujii H, Saka M, Mizoguchi K, Hirata M, Sakurai T, Takeuchi Y, Minamiguchi S, Arakawa Y, Haga H
J Clin Exp Hematop 2024;64(3):203-207. doi: 10.3960/jslrt.24025. PMID: 39343609Free PMC Article
Schorb E, Fox CP, Kasenda B, Linton K, Martinez-Calle N, Calimeri T, Ninkovic S, Eyre TA, Cummin T, Smith J, Yallop D, De Marco B, Krampera M, Trefz S, Orsucci L, Fabbri A, Illerhaus G, Cwynarski K, Ferreri AJM
Br J Haematol 2020 Jun;189(5):879-887. Epub 2020 Jan 29 doi: 10.1111/bjh.16451. PMID: 31997308
Guo S, Bai Q, Rohr J, Wang Y, Liu Y, Zeng K, Yu K, Zhang X, Wang Z
APMIS 2016 Dec;124(12):1054-1062. Epub 2016 Nov 2 doi: 10.1111/apm.12623. PMID: 27807891

Therapy

Akhtar OS, Arshad S, Lian Q, Ahn KW, D'Souza A, Dhakal B, Mohan M, Pasquini M, Longo W, Shah NN, Fenske TS, Hamadani M
Transplant Cell Ther 2024 Dec;30(12):1191.e1-1191.e8. Epub 2024 Sep 18 doi: 10.1016/j.jtct.2024.09.015. PMID: 39303985
Schorb E, Fox CP, Kasenda B, Linton K, Martinez-Calle N, Calimeri T, Ninkovic S, Eyre TA, Cummin T, Smith J, Yallop D, De Marco B, Krampera M, Trefz S, Orsucci L, Fabbri A, Illerhaus G, Cwynarski K, Ferreri AJM
Br J Haematol 2020 Jun;189(5):879-887. Epub 2020 Jan 29 doi: 10.1111/bjh.16451. PMID: 31997308

Prognosis

Guo S, Bai Q, Rohr J, Wang Y, Liu Y, Zeng K, Yu K, Zhang X, Wang Z
APMIS 2016 Dec;124(12):1054-1062. Epub 2016 Nov 2 doi: 10.1111/apm.12623. PMID: 27807891

Clinical prediction guides

Odani K, Fujimoto M, Fujii H, Saka M, Mizoguchi K, Hirata M, Sakurai T, Takeuchi Y, Minamiguchi S, Arakawa Y, Haga H
J Clin Exp Hematop 2024;64(3):203-207. doi: 10.3960/jslrt.24025. PMID: 39343609Free PMC Article
Guo S, Bai Q, Rohr J, Wang Y, Liu Y, Zeng K, Yu K, Zhang X, Wang Z
APMIS 2016 Dec;124(12):1054-1062. Epub 2016 Nov 2 doi: 10.1111/apm.12623. PMID: 27807891

Supplemental Content

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    Clinical resources

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