U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cleft vertebral arch

MedGen UID:
395267
•Concept ID:
C1859458
•
Congenital Abnormality; Finding
Synonym: Cleft vertebral arches
 
HPO: HP:0004616

Definition

A discontinuity of the vertebral arch, i.e., of the posterior part of a vertebra. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCleft vertebral arch

Conditions with this feature

Osteodysplastic primordial dwarfism, type 1
MedGen UID:
347149
•Concept ID:
C1859452
•
Congenital Abnormality
Microcephalic osteodysplastic primordial dwarfism type I (MOPD1) is a severe autosomal recessive skeletal dysplasia characterized by dwarfism, microcephaly, and neurologic abnormalities, including mental retardation, brain malformations, and ocular/auditory sensory deficits. Patients often die in early childhood (summary by Pierce and Morse, 2012).
See: Condition Record
Osteodysplastic primordial dwarfism, type 1

Professional guidelines

PubMed

A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with bone deficiency at the vertebral anterior border: A minimum 3-year follow-up study.
Wang B, Wang Y, Zhang H, Yan L, Kong L, He S, Hao D
Clin Neurol Neurosurg 2021 Feb;201:106434. Epub 2020 Dec 17 doi: 10.1016/j.clineuro.2020.106434. PMID: 33370625
Risk factors for conservative treatment failure in acute osteoporotic vertebral compression fractures (OVCFs).
Zhang J, He X, Fan Y, Du J, Hao D
Arch Osteoporos 2019 Feb 26;14(1):24. doi: 10.1007/s11657-019-0563-8. PMID: 30806831
Percutaneous Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures With Intravertebral Fluid or Air: A Comparative Study.
Niu J, Song D, Zhou H, Meng Q, Meng B, Yang H
Clin Spine Surg 2017 Oct;30(8):367-373. doi: 10.1097/BSD.0000000000000262. PMID: 28937459

Recent clinical studies

Etiology

Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
Radiological findings as favorable predictors of pain relief in patients with osteoporotic compression fractures after percutaneous vertebroplasty: a retrospective study of 156 cases.
Hirakawa M, Kobayashi N, Ishiyama M, Fuwa S, Saida Y, Honda H, Numaguchi Y
Jpn J Radiol 2012 Jun;30(5):407-14. Epub 2012 Feb 28 doi: 10.1007/s11604-012-0062-y. PMID: 22367775
Unipedicle percutaneous vertebroplasty for spinal intraosseous vacuum cleft.
Chen LH, Lai PL, Chen WJ
Clin Orthop Relat Res 2005 Jun;(435):148-53. doi: 10.1097/01.blo.0000155346.12405.70. PMID: 15930932
Rhizomelic chondrodysplasia punctata and survival beyond one year: a review of the literature and five case reports.
Wardinsky TD, Pagon RA, Powell BR, McGillivray B, Stephan M, Zonana J, Moser A
Clin Genet 1990 Aug;38(2):84-93. doi: 10.1111/j.1399-0004.1990.tb03554.x. PMID: 2208770

Diagnosis

Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
Coronal clefts in infants - rare differential diagnosis of traumatic injuries of vertebral bodies in battered children.
Doberentz E, Madea B, Müller AM
Leg Med (Tokyo) 2014 Nov;16(6):333-6. Epub 2014 Jul 15 doi: 10.1016/j.legalmed.2014.06.011. PMID: 25082734
Case report: imaging findings in a "butterfly" vertebra.
Boulet C, Schiettecatte A, De Mey J, De Maeseneer M
Acta Neurol Belg 2011 Dec;111(4):344-8. PMID: 22368979
Avascular necrosis of the vertebral body: MR imaging.
Naul LG, Peet GJ, Maupin WB
Radiology 1989 Jul;172(1):219-22. doi: 10.1148/radiology.172.1.2740507. PMID: 2740507
The early origin of vertebral anomalies, as illustrated by a 'butterfly vertebra'.
Müller F, O'Rahilly R, Benson DR
J Anat 1986 Dec;149:157-69. PMID: 3693103Free PMC Article

Therapy

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
Radiological findings as favorable predictors of pain relief in patients with osteoporotic compression fractures after percutaneous vertebroplasty: a retrospective study of 156 cases.
Hirakawa M, Kobayashi N, Ishiyama M, Fuwa S, Saida Y, Honda H, Numaguchi Y
Jpn J Radiol 2012 Jun;30(5):407-14. Epub 2012 Feb 28 doi: 10.1007/s11604-012-0062-y. PMID: 22367775
Refracture with cement extrusion following percutaneous vertebroplasty of a large interbody cleft.
Wagner AL, Baskurt E
AJNR Am J Neuroradiol 2006 Jan;27(1):230-1. PMID: 16418390Free PMC Article

Prognosis

Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
Radiological findings as favorable predictors of pain relief in patients with osteoporotic compression fractures after percutaneous vertebroplasty: a retrospective study of 156 cases.
Hirakawa M, Kobayashi N, Ishiyama M, Fuwa S, Saida Y, Honda H, Numaguchi Y
Jpn J Radiol 2012 Jun;30(5):407-14. Epub 2012 Feb 28 doi: 10.1007/s11604-012-0062-y. PMID: 22367775
A case of split notochord syndrome: presence of dorsal enteric diverticulum adjacent to the dorsal enteric fistula.
Akgür FM, Ozdemir T, Olguner M, Erbayraktar S, Ozer E, Aktuğ T
J Pediatr Surg 1998 Aug;33(8):1317-9. doi: 10.1016/s0022-3468(98)90179-8. PMID: 9722015
Rhizomelic chondrodysplasia punctata and survival beyond one year: a review of the literature and five case reports.
Wardinsky TD, Pagon RA, Powell BR, McGillivray B, Stephan M, Zonana J, Moser A
Clin Genet 1990 Aug;38(2):84-93. doi: 10.1111/j.1399-0004.1990.tb03554.x. PMID: 2208770

Clinical prediction guides

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
Development and internal validation of a clinical prediction model for acute adjacent vertebral fracture after vertebral augmentation : the AVA score.
Hijikata Y, Kamitani T, Nakahara M, Kumamoto S, Sakai T, Itaya T, Yamazaki H, Ogawa Y, Kusumegi A, Inoue T, Yoshida T, Furue N, Fukuhara SI, Yamamoto Y; AVA Score Research Group
Bone Joint J 2022 Jan;104-B(1):97-102. doi: 10.1302/0301-620X.104B1.BJJ-2021-0151.R3. PMID: 34969274
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Radiological findings as favorable predictors of pain relief in patients with osteoporotic compression fractures after percutaneous vertebroplasty: a retrospective study of 156 cases.
Hirakawa M, Kobayashi N, Ishiyama M, Fuwa S, Saida Y, Honda H, Numaguchi Y
Jpn J Radiol 2012 Jun;30(5):407-14. Epub 2012 Feb 28 doi: 10.1007/s11604-012-0062-y. PMID: 22367775
Intradermal dermoid cyst associated with occult spinal dysraphism.
Misago N, Abe M, Kohda H
J Dermatol 1996 Apr;23(4):275-8. doi: 10.1111/j.1346-8138.1996.tb04012.x. PMID: 8935344

Recent systematic reviews

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On
    • Cleft vertebral arch
      Cleft vertebral arch
      MedGen
    • Leukemia, Erythroblastic, Acute
      Leukemia, Erythroblastic, Acute
      A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripher...<br/>Year introduced: 1989
      MeSH
    • Animal Testing Alternatives
      Animal Testing Alternatives
      Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories....<br/>Year introduced: 1985
      MeSH

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...