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Post-transfusion thrombocytopenia

MedGen UID:
401404
•Concept ID:
C1868252
•
Finding
Synonym: Post-transfusion purpura
 
HPO: HP:0004813

Definition

Sudden onset of thrombocytopenia (reduced platelet count) within 5-10 days of the transfusion of blood products. The clinical presentation is post-transfusion purpura (PTP), wigth severe thrmbocytopenia, epistaxis, and hemorrhages. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPost-transfusion thrombocytopenia

Professional guidelines

PubMed

Cold stored platelets in the management of bleeding: is it about bioenergetics?
George CE, Saunders CV, Morrison A, Scorer T, Jones S, Dempsey NC
Platelets 2023 Dec;34(1):2188969. doi: 10.1080/09537104.2023.2188969. PMID: 36922733
Treatment of chemotherapy-induced thrombocytopenia in patients with non-hematologic malignancies.
Kuter DJ
Haematologica 2022 Jun 1;107(6):1243-1263. doi: 10.3324/haematol.2021.279512. PMID: 35642485Free PMC Article
Management of patients refractory to platelet transfusion.
Chockalingam P, Sacher RA
J Infus Nurs 2007 Jul-Aug;30(4):220-5. doi: 10.1097/01.NAN.0000281531.97183.c0. PMID: 17667077

Recent clinical studies

Etiology

Post-transfusion thrombocytopenia in recipients with anti-HLA antibody.
Ohto H, Yasuda H, Maeda H, Inaba S
Transfus Sci 2000 Dec;23(3):271-3. doi: 10.1016/s0955-3886(00)00108-9. PMID: 11099915

Supplemental Content

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