Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Cerebral atherosclerosis

MedGen UID:: 40189
•Concept ID:: C0007775
•: Disease or Syndrome

Synonyms:	Atheroscleroses, Cerebral; Atherosclerosis, Cerebral; Cerebral Atheroscleroses; Cerebral Atherosclerosis
SNOMED CT:	ICAS - intracranial atherosclerosis (55382008); ICAD - intracranial atherosclerotic disease (55382008); Atherosclerosis of intracranial artery (55382008); Cerebral atherosclerosis (55382008)

Monarch Initiative:	MONDO:0006694

Definition

Atherosclerosis of the cerebral vasculature. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCerebral atherosclerosis

Abnormal cardiovascular system morphology
- Abnormal vascular morphology
  - Abnormal blood vessel morphology
    - Abnormal systemic arterial morphology
      - Arteriosclerosis disorder
        Atherosclerosis
        Cerebral atherosclerosis

Professional guidelines

PubMed

Oral anticoagulants: A plausible new treatment for Alzheimer's disease?

Toribio-Fernandez R, Ceron C, Tristão-Pereira C, Fernandez-Nueda I, Perez-Castillo A, Fernandez-Ferro J, Moro MA, Ibañez B, Fuster V, Cortes-Canteli M
Br J Pharmacol 2024 Mar;181(6):760-776. Epub 2023 Jan 31 doi: 10.1111/bph.16032. PMID: 36633908

Understanding the molecular mechanism of Ginkgo Folium-Forsythiae Fructus for cerebral atherosclerosis treatment using network pharmacology and molecular docking.

Zhang J, Gai J, Ma H, Tang J, Yang C, Zu G
Medicine (Baltimore) 2023 Feb 17;102(7):e32823. doi: 10.1097/MD.0000000000032823. PMID: 36800633 Free PMC Article

Hypothermia dn alphamethyldopa treatment.

Chandramohan M, Hariharasubramanian N, Johnson ES, Devi SP
Indian J Physiol Pharmacol 1976 Oct-Dec;20(4):216-20. PMID: 1010637

See all (17)

Recent clinical studies

Etiology

Pre-Admission CHADS2 and CHA2DS2-VASc Scores on Early Neurological Worsening.

Nam KW, Kim CK, Yu S, Chung JW, Bang OY, Kim GM, Jung JM, Song TJ, Kim YJ, Kim BJ, Heo SH, Park KY, Kim JM, Park JH, Choi JC, Park MS, Kim JT, Choi KH, Hwang YH, Oh K, Seo WK
Cerebrovasc Dis 2021;50(3):288-295. Epub 2021 Feb 15 doi: 10.1159/000513396. PMID: 33588410

Pathological Characteristics.

Chen XY, Fisher M
Front Neurol Neurosci 2016;40:21-33. Epub 2016 Dec 2 doi: 10.1159/000448267. PMID: 27960191 Free PMC Article

Paraoxonase 1 in neurological disorders.

Menini T, Gugliucci A
Redox Rep 2014 Mar;19(2):49-58. Epub 2013 Nov 12 doi: 10.1179/1351000213Y.0000000071. PMID: 24225313 Free PMC Article

A critique of the Women's Health Initiative hormone therapy study.

Klaiber EL, Vogel W, Rako S
Fertil Steril 2005 Dec;84(6):1589-601. doi: 10.1016/j.fertnstert.2005.08.010. PMID: 16359951

Cerebral atherosclerosis in Uganda.

Owor R, Resch JA, Loewenson RB
Stroke 1976 Jul-Aug;7(4):404-6. doi: 10.1161/01.str.7.4.404. PMID: 960161

See all (192)

Diagnosis

Pre-Admission CHADS2 and CHA2DS2-VASc Scores on Early Neurological Worsening.

Fluorescent probes sensitive to changes in the cholesterol-to-phospholipids molar ratio in human platelet membranes during atherosclerosis.

Posokhov Y
Methods Appl Fluoresc 2016 Sep 14;4(3):034013. doi: 10.1088/2050-6120/4/3/034013. PMID: 28355159

Risk Factors.

Uehara T, Bang OY, Kim JS, Minematsu K, Sacco R
Front Neurol Neurosci 2016;40:47-57. Epub 2016 Dec 2 doi: 10.1159/000448301. PMID: 27960158

Barostim Implantation with Ipsilateral Carotid Endarterectomy as a One-Stage Procedure.

Weipert KF, Most A, Doerr O, Koshty A, Hamm CW, Erkapic D, Schmitt J
Ann Vasc Surg 2016 Oct;36:295.e9-295.e11. Epub 2016 Jul 15 doi: 10.1016/j.avsg.2016.03.026. PMID: 27423727

Red blood cell aggregation changes are depended on its initial value: Effect of long-term drug treatment and short-term cell incubation with drug.

Muravyov AV, Tikhomirova IA, Maimistova AA, Bulaeva SV, Mikhailov PV, Kislov NV
Clin Hemorheol Microcirc 2011;48(4):231-40. doi: 10.3233/CH-2011-1415. PMID: 22012828

See all (77)

Therapy

Two-sample Mendelian randomization to study the causal association between gut microbiota and atherosclerosis.

Jiang S, Yu C, Lv B, He S, Zheng Y, Yang W, Wang B, Li D, Lin J
Front Immunol 2023;14:1282072. Epub 2024 Jan 12 doi: 10.3389/fimmu.2023.1282072. PMID: 38283337 Free PMC Article

Sodium-glucose cotransporter 2 inhibitor ameliorates high fat diet-induced hypothalamic-pituitary-ovarian axis disorders.

Chen X, Huang L, Cui L, Xiao Z, Xiong X, Chen C
J Physiol 2022 Nov;600(21):4549-4568. Epub 2022 Sep 20 doi: 10.1113/JP283259. PMID: 36048516 Free PMC Article

Antithrombotic Therapy.

Kwon SU, Kim JS
Front Neurol Neurosci 2016;40:141-151. Epub 2016 Dec 2 doi: 10.1159/000448310. PMID: 27960183

Barostim Implantation with Ipsilateral Carotid Endarterectomy as a One-Stage Procedure.

Weipert KF, Most A, Doerr O, Koshty A, Hamm CW, Erkapic D, Schmitt J
Ann Vasc Surg 2016 Oct;36:295.e9-295.e11. Epub 2016 Jul 15 doi: 10.1016/j.avsg.2016.03.026. PMID: 27423727

Cerebral atherosclerosis.

Beckett HD
Br Med J 1971 Aug 14;3(5771):434. doi: 10.1136/bmj.3.5771.434-b. PMID: 5566636 Free PMC Article

See all (49)

Prognosis

Cerebral atherosclerosis and early ischemic stroke after left-sided valve replacement surgery.

Kim HJ, Lee EJ, Jung SH, Lee JW, Kim JS, Kim JB, Kwon SU
J Thorac Cardiovasc Surg 2022 Mar;163(3):967-976.e6. Epub 2020 May 13 doi: 10.1016/j.jtcvs.2020.05.002. PMID: 32616350

Progress on diabetic cerebrovascular diseases.

Zhou H, Zhang X, Lu J
Bosn J Basic Med Sci 2014 Nov 9;14(4):185-90. doi: 10.17305/bjbms.2014.4.203. PMID: 25428668 Free PMC Article

Paraoxonase 1 in neurological disorders.

Menini T, Gugliucci A
Redox Rep 2014 Mar;19(2):49-58. Epub 2013 Nov 12 doi: 10.1179/1351000213Y.0000000071. PMID: 24225313 Free PMC Article

Are stroke biomarkers seeing brain vessels in patients with ischemic stroke?: a C-reactive protein and homocysteine study.

Kim SJ, Choe YH, Bang OY; CHAOS-BIOMARKER Collaborators
Stroke 2011 May;42(5):1464-8. Epub 2011 Mar 24 doi: 10.1161/STROKEAHA.110.607432. PMID: 21441154

Severe anemia associated with transient neurological deficits.

Shahar A, Sadeh M
Stroke 1991 Sep;22(9):1201-2. doi: 10.1161/01.str.22.9.1201. PMID: 1926264

See all (72)

Clinical prediction guides

Two-sample Mendelian randomization to study the causal association between gut microbiota and atherosclerosis.

Jiang S, Yu C, Lv B, He S, Zheng Y, Yang W, Wang B, Li D, Lin J
Front Immunol 2023;14:1282072. Epub 2024 Jan 12 doi: 10.3389/fimmu.2023.1282072. PMID: 38283337 Free PMC Article

Pre-Admission CHADS2 and CHA2DS2-VASc Scores on Early Neurological Worsening.

Are stroke biomarkers seeing brain vessels in patients with ischemic stroke?: a C-reactive protein and homocysteine study.

Kim SJ, Choe YH, Bang OY; CHAOS-BIOMARKER Collaborators
Stroke 2011 May;42(5):1464-8. Epub 2011 Mar 24 doi: 10.1161/STROKEAHA.110.607432. PMID: 21441154

Risk factors of intracranial cerebral atherosclerosis among asymptomatics.

Bae HJ, Lee J, Park JM, Kwon O, Koo JS, Kim BK, Pandey DK
Cerebrovasc Dis 2007;24(4):355-60. Epub 2007 Aug 9 doi: 10.1159/000106982. PMID: 17690548

A critique of the Women's Health Initiative hormone therapy study.

Klaiber EL, Vogel W, Rako S
Fertil Steril 2005 Dec;84(6):1589-601. doi: 10.1016/j.fertnstert.2005.08.010. PMID: 16359951

See all (102)