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Chronic tic disorder

MedGen UID:
40301
•Concept ID:
C0008701
•
Mental or Behavioral Dysfunction
Synonyms: Chronic Motor or Vocal Tic Disorder; Motor or Vocal Tic Disorder, Chronic; Tic Disorder, Chronic Motor or Vocal
 
Monarch Initiative: MONDO:0001074

Definition

A neurological disorder presenting in childhood that is characterized by either motor or phonic tics, but not both, that occur daily or nearly daily for at least a year and are not attributed to an identifiable cause. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic tic disorder

Professional guidelines

PubMed

Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment.
Zinna S, Luxton R, Papachristou E, Dima D, Kyriakopoulos M
Clin Child Psychol Psychiatry 2021 Jul;26(3):894-905. Epub 2021 Apr 16 doi: 10.1177/13591045211007918. PMID: 33860687
Progress in Pharmacological and Surgical Management of Tourette Syndrome and Other Chronic Tic Disorders.
Pandey S, Dash D
Neurologist 2019 May;24(3):93-108. doi: 10.1097/NRL.0000000000000218. PMID: 31045720
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article

Recent clinical studies

Etiology

Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study.
Rizzo R, Prato A, Scerbo M, Saia F, Barone R, Curatolo P
Nutrients 2022 Feb 18;14(4) doi: 10.3390/nu14040852. PMID: 35215501Free PMC Article
Insomnia in Tourette Syndrome and Chronic Tic Disorder.
Isomura K, Sidorchuk A, Sevilla-Cermeño L, Åkerstedt T, Silverberg-Morse M, Larsson H, Mataix-Cols D, Fernández de la Cruz L
Mov Disord 2022 Feb;37(2):392-400. Epub 2021 Oct 24 doi: 10.1002/mds.28842. PMID: 34693569
Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment.
Zinna S, Luxton R, Papachristou E, Dima D, Kyriakopoulos M
Clin Child Psychol Psychiatry 2021 Jul;26(3):894-905. Epub 2021 Apr 16 doi: 10.1177/13591045211007918. PMID: 33860687
General health and mortality in Tourette syndrome and chronic tic disorder: A mini-review.
Fernández de la Cruz L, Mataix-Cols D
Neurosci Biobehav Rev 2020 Dec;119:514-520. Epub 2020 Nov 11 doi: 10.1016/j.neubiorev.2020.11.005. PMID: 33188819
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article

Diagnosis

Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.
Mataix-Cols D, Isomura K, Brander G, Brikell I, Lichtenstein P, Chang Z, Larsson H, Kuja-Halkola R, Black KJ, Sidorchuk A, Fernández de la Cruz L
Mov Disord 2023 Aug;38(8):1419-1427. Epub 2023 May 29 doi: 10.1002/mds.29454. PMID: 37246931
Childhood Neurologic Conditions: Movement Disorders.
Youssef P
FP Essent 2022 Dec;523:20-26. PMID: 36459665
Association of Tourette Syndrome and Chronic Tic Disorder With Violent Assault and Criminal Convictions.
Mataix-Cols D, Virtanen S, Sidorchuk A, Fernández de la Cruz L, Larsson H, Lichtenstein P, Latvala A
JAMA Neurol 2022 May 1;79(5):459-467. doi: 10.1001/jamaneurol.2022.0167. PMID: 35311941Free PMC Article
Insomnia in Tourette Syndrome and Chronic Tic Disorder.
Isomura K, Sidorchuk A, Sevilla-Cermeño L, Åkerstedt T, Silverberg-Morse M, Larsson H, Mataix-Cols D, Fernández de la Cruz L
Mov Disord 2022 Feb;37(2):392-400. Epub 2021 Oct 24 doi: 10.1002/mds.28842. PMID: 34693569
Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment.
Zinna S, Luxton R, Papachristou E, Dima D, Kyriakopoulos M
Clin Child Psychol Psychiatry 2021 Jul;26(3):894-905. Epub 2021 Apr 16 doi: 10.1177/13591045211007918. PMID: 33860687

Therapy

Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study.
Rizzo R, Prato A, Scerbo M, Saia F, Barone R, Curatolo P
Nutrients 2022 Feb 18;14(4) doi: 10.3390/nu14040852. PMID: 35215501Free PMC Article
Association of Tourette Syndrome and Chronic Tic Disorder With Cervical Spine Disorders and Related Neurological Complications.
Isung J, Isomura K, Larsson H, Sidorchuk A, Fernández de la Cruz L, Mataix-Cols D
JAMA Neurol 2021 Oct 1;78(10):1205-1211. doi: 10.1001/jamaneurol.2021.2798. PMID: 34424277Free PMC Article
Effectiveness of Behaviour Therapy for Children and Adolescents with Tourette Syndrome and Chronic Tic Disorder in a Naturalistic Setting.
Andrén P, Wachtmeister V, Franzé J, Speiner C, Fernández de la Cruz L, Andersson E, de Schipper E, Rautio D, Silverberg-Mörse M, Serlachius E, Mataix-Cols D
Child Psychiatry Hum Dev 2021 Aug;52(4):739-750. Epub 2020 Dec 14 doi: 10.1007/s10578-020-01098-y. PMID: 33315190Free PMC Article
Progress in Pharmacological and Surgical Management of Tourette Syndrome and Other Chronic Tic Disorders.
Pandey S, Dash D
Neurologist 2019 May;24(3):93-108. doi: 10.1097/NRL.0000000000000218. PMID: 31045720
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article

Prognosis

Functional tic-like presentations differ strikingly from Provisional Tic Disorder.
Arbuckle AL, Bihun EC, Schlaggar BL, Black KJ
F1000Res 2022;11:1566. Epub 2023 Apr 17 doi: 10.12688/f1000research.129252.2. PMID: 37224324Free PMC Article
Cross-disorder comparison of sensory over-responsivity in chronic tic disorders and obsessive-compulsive disorder.
Isaacs D, Key AP, Cascio CJ, Conley AC, Riordan H, Walker HC, Wallace MT, Claassen DO
Compr Psychiatry 2022 Feb;113:152291. Epub 2021 Dec 17 doi: 10.1016/j.comppsych.2021.152291. PMID: 34952304Free PMC Article
Olfactory functioning in adults with Tourette syndrome.
Kronenbuerger M, Belenghi P, Ilgner J, Freiherr J, Hummel T, Neuner I
PLoS One 2018;13(6):e0197598. Epub 2018 Jun 6 doi: 10.1371/journal.pone.0197598. PMID: 29874283Free PMC Article
Suicide in Tourette's and Chronic Tic Disorders.
Fernández de la Cruz L, Rydell M, Runeson B, Brander G, Rück C, D'Onofrio BM, Larsson H, Lichtenstein P, Mataix-Cols D
Biol Psychiatry 2017 Jul 15;82(2):111-118. Epub 2016 Aug 26 doi: 10.1016/j.biopsych.2016.08.023. PMID: 27773353
Mindfulness-based stress reduction for Tourette Syndrome and Chronic Tic Disorder: a pilot study.
Reese HE, Vallejo Z, Rasmussen J, Crowe K, Rosenfield E, Wilhelm S
J Psychosom Res 2015 Mar;78(3):293-8. Epub 2014 Aug 10 doi: 10.1016/j.jpsychores.2014.08.001. PMID: 25149879

Clinical prediction guides

Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.
Mataix-Cols D, Isomura K, Brander G, Brikell I, Lichtenstein P, Chang Z, Larsson H, Kuja-Halkola R, Black KJ, Sidorchuk A, Fernández de la Cruz L
Mov Disord 2023 Aug;38(8):1419-1427. Epub 2023 May 29 doi: 10.1002/mds.29454. PMID: 37246931
Functional tic-like presentations differ strikingly from Provisional Tic Disorder.
Arbuckle AL, Bihun EC, Schlaggar BL, Black KJ
F1000Res 2022;11:1566. Epub 2023 Apr 17 doi: 10.12688/f1000research.129252.2. PMID: 37224324Free PMC Article
Cross-disorder comparison of sensory over-responsivity in chronic tic disorders and obsessive-compulsive disorder.
Isaacs D, Key AP, Cascio CJ, Conley AC, Riordan H, Walker HC, Wallace MT, Claassen DO
Compr Psychiatry 2022 Feb;113:152291. Epub 2021 Dec 17 doi: 10.1016/j.comppsych.2021.152291. PMID: 34952304Free PMC Article
Mycoplasma pneumoniae IgG positivity is associated with tic severity in chronic tic disorders.
Schnell J, Bond M, Moll N, Weidinger E, Burger B, Bond R, Dietrich A, Hoekstra PJ, Schrag A, Martino D, Schwarz M, Meier UC, Müller N
Brain Behav Immun 2022 Jan;99:281-288. Epub 2021 Oct 24 doi: 10.1016/j.bbi.2021.10.012. PMID: 34699932
Suicide in Tourette's and Chronic Tic Disorders.
Fernández de la Cruz L, Rydell M, Runeson B, Brander G, Rück C, D'Onofrio BM, Larsson H, Lichtenstein P, Mataix-Cols D
Biol Psychiatry 2017 Jul 15;82(2):111-118. Epub 2016 Aug 26 doi: 10.1016/j.biopsych.2016.08.023. PMID: 27773353

Recent systematic reviews

The correlation between prenatal maternal active smoking and neurodevelopmental disorders in children: a systematic review and meta-analysis.
Chen D, Niu Q, Liu S, Shao W, Huang Y, Xu Y, Li Y, Liu J, Wang X, Yang H
BMC Public Health 2023 Mar 30;23(1):611. doi: 10.1186/s12889-023-15496-z. PMID: 36997899Free PMC Article
Rage attacks in Tourette Syndrome and Chronic Tic Disorder: a systematic review.
Conte G, Valente F, Fioriello F, Cardona F
Neurosci Biobehav Rev 2020 Dec;119:21-36. Epub 2020 Sep 25 doi: 10.1016/j.neubiorev.2020.09.019. PMID: 32980398
Streptococcal Infections and Exacerbations in PANDAS: A Systematic Review and Meta-analysis.
Nielsen MØ, Köhler-Forsberg O, Hjorthøj C, Benros ME, Nordentoft M, Orlovska-Waast S
Pediatr Infect Dis J 2019 Feb;38(2):189-194. doi: 10.1097/INF.0000000000002218. PMID: 30325890
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
The prevalence of tic disorders for children in China: A systematic review and meta-analysis.
Yang C, Zhang L, Zhu P, Zhu C, Guo Q
Medicine (Baltimore) 2016 Jul;95(30):e4354. doi: 10.1097/MD.0000000000004354. PMID: 27472724Free PMC Article

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