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Obsessive-compulsive personality disorder

MedGen UID:
40432
•Concept ID:
C0009595
•
Mental or Behavioral Dysfunction
Synonyms: Obsessive Compulsive Personality; Obsessive-Compulsive Personalities; Obsessive-Compulsive Personality; Personalities, Obsessive-Compulsive; Personality, Obsessive-Compulsive
SNOMED CT: Obsessive-compulsive personality trait (112091009); Obsessive compulsive personality disorder (1376001); Anancastic personality disorder (1376001); Anankastic personality disorder (1376001)
 
Monarch Initiative: MONDO:0001158

Definition

A disorder characterized by an enduring pattern of inflexibility, extreme orderliness, and perfectionism which interfere with efficiency and which may manifest in many different contexts, including work and leisure activities, financial matters, and issues of morality or ethics. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVObsessive-compulsive personality disorder

Professional guidelines

PubMed

Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis.
Yao Y, Guo D, Lu TS, Liu FL, Huang SH, Diao MQ, Li SX, Zhang XJ, Kosten TR, Shi J, Bao YP, Lu L, Han Y
Psychiatry Res 2024 May;335:115886. Epub 2024 Mar 28 doi: 10.1016/j.psychres.2024.115886. PMID: 38574699
Obsessive compulsive personality disorder and obsessive compulsive disorder: clinical characteristics, diagnostic difficulties, and treatment.
Mancebo MC, Eisen JL, Grant JE, Rasmussen SA
Ann Clin Psychiatry 2005 Oct-Dec;17(4):197-204. doi: 10.1080/10401230500295305. PMID: 16402751
Psychogenic excoriation. Clinical features, proposed diagnostic criteria, epidemiology and approaches to treatment.
Arnold LM, Auchenbach MB, McElroy SL
CNS Drugs 2001;15(5):351-9. doi: 10.2165/00023210-200115050-00002. PMID: 11475941

Recent clinical studies

Etiology

Is obsessive-compulsive personality disorder related to stress-related exhaustion?
Gulin S, Ellbin S, Jonsdottir IH, Lindqvist Bagge AS
Brain Behav 2021 Jun;11(6):e02171. Epub 2021 May 10 doi: 10.1002/brb3.2171. PMID: 33969937Free PMC Article
Intolerance of uncertainty and obsessive-compulsive personality disorder.
Wheaton MG, Ward HE
Personal Disord 2020 Sep;11(5):357-364. Epub 2020 Feb 17 doi: 10.1037/per0000396. PMID: 32068417
Altered spontaneous brain activity in obsessive-compulsive personality disorder.
Lei H, Huang L, Li J, Liu W, Fan J, Zhang X, Xia J, Zhao K, Zhu X, Rao H
Compr Psychiatry 2020 Jan;96:152144. Epub 2019 Nov 5 doi: 10.1016/j.comppsych.2019.152144. PMID: 31707312
Personality and temperament.
Lilenfeld LR
Curr Top Behav Neurosci 2011;6:3-16. doi: 10.1007/7854_2010_86. PMID: 21243467
Obsessive-compulsive disorder: boundary issues.
Fineberg NA, Saxena S, Zohar J, Craig KJ
CNS Spectr 2007 May;12(5):359-64, 367-375. doi: 10.1017/s1092852900021167. PMID: 17514081

Diagnosis

The impact of obsessive-compulsive personality disorder in perfectionism.
Redden SA, Mueller NE, Cougle JR
Int J Psychiatry Clin Pract 2023 Mar;27(1):18-24. Epub 2022 May 4 doi: 10.1080/13651501.2022.2069581. PMID: 35507830
Commentary: Diagnostic Challenges.
Garakani A
J Psychiatr Pract 2022 May 1;28(3):270-271. doi: 10.1097/PRA.0000000000000630. PMID: 35511106
Current understanding of the relationships between obsessive-compulsive disorder and personality disturbance.
Starcevic V, Brakoulias V
Curr Opin Psychiatry 2017 Jan;30(1):50-55. doi: 10.1097/YCO.0000000000000291. PMID: 27755142
Obsessive-compulsive personality disorder: a current review.
Diedrich A, Voderholzer U
Curr Psychiatry Rep 2015 Feb;17(2):2. doi: 10.1007/s11920-014-0547-8. PMID: 25617042
Personality and temperament.
Lilenfeld LR
Curr Top Behav Neurosci 2011;6:3-16. doi: 10.1007/7854_2010_86. PMID: 21243467

Therapy

The impact of obsessive-compulsive personality disorder in perfectionism.
Redden SA, Mueller NE, Cougle JR
Int J Psychiatry Clin Pract 2023 Mar;27(1):18-24. Epub 2022 May 4 doi: 10.1080/13651501.2022.2069581. PMID: 35507830
Efficacy and tolerability of pharmacotherapy for obsessive-compulsive personality disorder: a systematic review of randomized controlled trials.
Gecaite-Stonciene J, Williams T, Lochner C, Hoffman J, Stein DJ
Expert Opin Pharmacother 2022 Aug;23(11):1351-1358. Epub 2022 Jul 15 doi: 10.1080/14656566.2022.2100695. PMID: 35818708
Predictors of personality disorders in prisoners.
Yousefi F, Talib MA
J Med Life 2022 Apr;15(4):454-461. doi: 10.25122/jml-2021-0317. PMID: 35646191Free PMC Article
Obsessive-compulsive (anankastic) personality disorder: toward the ICD-11 classification.
Fineberg NA, Reghunandanan S, Kolli S, Atmaca M
Braz J Psychiatry 2014;36 Suppl 1:40-50. doi: 10.1590/1516-4446-2013-1282. PMID: 25388611
Obsessive-compulsive disorder: boundary issues.
Fineberg NA, Saxena S, Zohar J, Craig KJ
CNS Spectr 2007 May;12(5):359-64, 367-375. doi: 10.1017/s1092852900021167. PMID: 17514081

Prognosis

Intolerance of uncertainty and obsessive-compulsive personality disorder.
Wheaton MG, Ward HE
Personal Disord 2020 Sep;11(5):357-364. Epub 2020 Feb 17 doi: 10.1037/per0000396. PMID: 32068417
Current understanding of the relationships between obsessive-compulsive disorder and personality disturbance.
Starcevic V, Brakoulias V
Curr Opin Psychiatry 2017 Jan;30(1):50-55. doi: 10.1097/YCO.0000000000000291. PMID: 27755142
Obsessive-compulsive personality disorder: a current review.
Diedrich A, Voderholzer U
Curr Psychiatry Rep 2015 Feb;17(2):2. doi: 10.1007/s11920-014-0547-8. PMID: 25617042
Timely topics in pediatric psychiatry.
Dineen Wagner K
J Clin Psychiatry 2014 Nov;75(11):1224-5. doi: 10.4088/JCP.14f09535. PMID: 25470084
Personality and temperament.
Lilenfeld LR
Curr Top Behav Neurosci 2011;6:3-16. doi: 10.1007/7854_2010_86. PMID: 21243467

Clinical prediction guides

Obsessive-compulsive personality disorder in rapid eye movement sleep behavior disorder.
Luca A, Cicero CE, Giuliano L, Sgroi R, Vancheri E, Terravecchia C, Squillaci R, Rascunà C, Donzuso G, Mostile G, Sciacca G, Zappia M, Nicoletti A
Sci Rep 2022 Feb 14;12(1):2401. doi: 10.1038/s41598-022-06424-z. PMID: 35165341Free PMC Article
Intolerance of uncertainty and obsessive-compulsive personality disorder.
Wheaton MG, Ward HE
Personal Disord 2020 Sep;11(5):357-364. Epub 2020 Feb 17 doi: 10.1037/per0000396. PMID: 32068417
Altered spontaneous brain activity in obsessive-compulsive personality disorder.
Lei H, Huang L, Li J, Liu W, Fan J, Zhang X, Xia J, Zhao K, Zhu X, Rao H
Compr Psychiatry 2020 Jan;96:152144. Epub 2019 Nov 5 doi: 10.1016/j.comppsych.2019.152144. PMID: 31707312
Obsessive-compulsive personality disorder: a current review.
Diedrich A, Voderholzer U
Curr Psychiatry Rep 2015 Feb;17(2):2. doi: 10.1007/s11920-014-0547-8. PMID: 25617042
Timely topics in pediatric psychiatry.
Dineen Wagner K
J Clin Psychiatry 2014 Nov;75(11):1224-5. doi: 10.4088/JCP.14f09535. PMID: 25470084

Recent systematic reviews

Efficacy and tolerability of pharmacotherapy for obsessive-compulsive personality disorder: a systematic review of randomized controlled trials.
Gecaite-Stonciene J, Williams T, Lochner C, Hoffman J, Stein DJ
Expert Opin Pharmacother 2022 Aug;23(11):1351-1358. Epub 2022 Jul 15 doi: 10.1080/14656566.2022.2100695. PMID: 35818708
The neurobiology of obsessive-compulsive personality disorder: a systematic review.
Marincowitz C, Lochner C, Stein DJ
CNS Spectr 2022 Dec;27(6):664-675. Epub 2021 Aug 11 doi: 10.1017/S1092852921000754. PMID: 34378500
Obsessive-Compulsive Personality Disorder Co-occurring in Individuals with Obsessive-Compulsive Disorder: A Systematic Review and Meta-analysis.
Pozza A, Starcevic V, Ferretti F, Pedani C, Crispino R, Governi G, Luchi S, Gallorini A, Lochner C, Coluccia A
Harv Rev Psychiatry 2021 Mar-Apr 01;29(2):95-107. doi: 10.1097/HRP.0000000000000287. PMID: 33666394
Prevalence of personality disorders in the general adult population in Western countries: systematic review and meta-analysis.
Volkert J, Gablonski TC, Rabung S
Br J Psychiatry 2018 Dec;213(6):709-715. Epub 2018 Sep 28 doi: 10.1192/bjp.2018.202. PMID: 30261937
Are obsessive-compulsive personality traits associated with a poor outcome in anorexia nervosa? A systematic review of randomized controlled trials and naturalistic outcome studies.
Crane AM, Roberts ME, Treasure J
Int J Eat Disord 2007 Nov;40(7):581-8. doi: 10.1002/eat.20419. PMID: 17607713

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