Abnormal positioning in which the elbows are turned out.

Increased thumb width without increased dorso-ventral dimension.

Medial deviation of the great toe owing to a deformity of the great toe joint causing the hallux to deviate medially.

A soft tissue continuity in the anteroposterior axis between adjacent foot digits that involves at least half of the proximodistal length of one of the two involved digits; or, a soft tissue continuity in the A/P axis between two digits of the foot that does not meet the prior objective criteria.

Visible increase in width of the hallux without an increase in the dorso-ventral dimension.

An abnormal osseous union (fusion) between the radius and the humerus.

An abnormality of skull shape characterized by a increased anterior-posterior diameter, i.e., an increased antero-posterior dimension of the skull. Cephalic index less than 76%. Alternatively, an apparently increased antero-posterior length of the head compared to width. Often due to premature closure of the sagittal suture.

Fusion involving two or more metacarpal bones (A synostosis of the first metacarpal and the proximal phalanx of the thumb can also be observed, note that the first metacarpal bone corresponds to a proximal phalanx).

Cleft palate is a developmental defect of the palate resulting from a failure of fusion of the palatine processes and manifesting as a separation of the roof of the mouth (soft and hard palate).

An eye that is protruding anterior to the plane of the face to a greater extent than is typical.