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Spinal Leptomeningeal Lesion

MedGen UID:
415990
Concept ID:
C2827411
Finding

Definition

A non-neoplastic or neoplastic pathologic process affecting the leptomeninges of the spinal cord. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpinal Leptomeningeal Lesion

Professional guidelines

PubMed

Chamberlain M, Junck L, Brandsma D, Soffietti R, Rudà R, Raizer J, Boogerd W, Taillibert S, Groves MD, Le Rhun E, Walker J, van den Bent M, Wen PY, Jaeckle KA
Neuro Oncol 2017 Apr 1;19(4):484-492. doi: 10.1093/neuonc/now183. PMID: 28039364Free PMC Article
Lawton CD, Nagasawa DT, Yang I, Fessler RG, Smith ZA
J Neurosurg Spine 2012 Nov;17(5):438-48. Epub 2012 Sep 7 doi: 10.3171/2012.7.SPINE12212. PMID: 22958073
Algazi AP, Kadoch C, Rubenstein JL
Neurotherapeutics 2009 Jul;6(3):587-97. doi: 10.1016/j.nurt.2009.04.013. PMID: 19560747Free PMC Article

Recent clinical studies

Etiology

Serrallach BL, Kralik SF, Tran BH, Huisman TAGM, Patel RP, Allen CE, McClain KL, Gulati N, Dillard-Ilboudo CQ, Hicks MJ, Mohila CA, Desai NK
AJNR Am J Neuroradiol 2022 Nov;43(11):1667-1673. Epub 2022 Oct 20 doi: 10.3174/ajnr.A7683. PMID: 36265894Free PMC Article
Bahranifard B, Mehdizadeh S, Hamidi A, Khosravi A, Emami R, Mirzaei K, Nemati R, Nemati F, Assadi M, Gholamrezanezhad A
Neuroradiol J 2022 Feb;35(1):3-24. Epub 2021 Jul 5 doi: 10.1177/19714009211029177. PMID: 34224248Free PMC Article
Ruggieri M, Polizzi A, Catanzaro S, Bianco ML, Praticò AD, Di Rocco C
Childs Nerv Syst 2020 Oct;36(10):2571-2596. Epub 2020 Oct 13 doi: 10.1007/s00381-020-04770-9. PMID: 33048248
Dormegny L, Chibbaro S, Ganau M, Santin M, Kremer L, Proust F
Neurochirurgie 2018 Dec;64(6):425-430. Epub 2018 Sep 19 doi: 10.1016/j.neuchi.2018.07.002. PMID: 30243464
Islam MP
Handb Clin Neurol 2015;132:111-7. doi: 10.1016/B978-0-444-62702-5.00007-X. PMID: 26564074

Diagnosis

Kurokawa R, Kurokawa M, Isshiki S, Harada T, Nakaya M, Baba A, Naganawa S, Kim J, Bapuraj J, Srinivasan A, Abe O, Moritani T
Radiographics 2023 Aug;43(9):e230039. doi: 10.1148/rg.230039. PMID: 37535461
Nieblas-Bedolla E, Zuccato J, Kluger H, Zadeh G, Brastianos PK
Hematol Oncol Clin North Am 2022 Feb;36(1):161-188. Epub 2021 Oct 25 doi: 10.1016/j.hoc.2021.08.004. PMID: 34711458
Ruggieri M, Polizzi A, Catanzaro S, Bianco ML, Praticò AD, Di Rocco C
Childs Nerv Syst 2020 Oct;36(10):2571-2596. Epub 2020 Oct 13 doi: 10.1007/s00381-020-04770-9. PMID: 33048248
Bot JCJ, Mazzai L, Hagenbeek RE, Ingala S, van Oosten B, Sanchez-Aliaga E, Barkhof F
Neuroradiology 2020 Mar;62(3):283-300. Epub 2020 Jan 10 doi: 10.1007/s00234-019-02335-5. PMID: 31925469Free PMC Article
Smirniotopoulos JG, Murphy FM, Rushing EJ, Rees JH, Schroeder JW
Radiographics 2007 Mar-Apr;27(2):525-51. doi: 10.1148/rg.272065155. PMID: 17374867

Therapy

Al Malik YM
Neurosciences (Riyadh) 2020 Oct;25(5):406-411. doi: 10.17712/nsj.2020.5.20200090. PMID: 33459292Free PMC Article
Chiavazza C, Pellerino A, Ferrio F, Cistaro A, Soffietti R, Rudà R
Biomed Res Int 2018;2018:3606970. Epub 2018 Jun 21 doi: 10.1155/2018/3606970. PMID: 30035121Free PMC Article
Mack F, Baumert BG, Schäfer N, Hattingen E, Scheffler B, Herrlinger U, Glas M
Cancer Treat Rev 2016 Feb;43:83-91. Epub 2015 Dec 24 doi: 10.1016/j.ctrv.2015.12.004. PMID: 26827696
Sohn M, Culver DA, Judson MA, Scott TF, Tavee J, Nozaki K
Am J Med Sci 2014 Mar;347(3):195-8. doi: 10.1097/MAJ.0b013e3182808781. PMID: 23364469
Grossman SA, Krabak MJ
Cancer Treat Rev 1999 Apr;25(2):103-19. doi: 10.1053/ctrv.1999.0119. PMID: 10395835

Prognosis

Chhabra R, Misra S, Prasad P, Khati S
Neurol India 2022 Sep-Oct;70(5):2153-2155. doi: 10.4103/0028-3886.359256. PMID: 36352627
Filippi M, Brück W, Chard D, Fazekas F, Geurts JJG, Enzinger C, Hametner S, Kuhlmann T, Preziosa P, Rovira À, Schmierer K, Stadelmann C, Rocca MA; Attendees of the Correlation between Pathological and MRI findings in MS workshop
Lancet Neurol 2019 Feb;18(2):198-210. doi: 10.1016/S1474-4422(18)30451-4. PMID: 30663609
Chiavazza C, Pellerino A, Ferrio F, Cistaro A, Soffietti R, Rudà R
Biomed Res Int 2018;2018:3606970. Epub 2018 Jun 21 doi: 10.1155/2018/3606970. PMID: 30035121Free PMC Article
Islam MP
Handb Clin Neurol 2015;132:111-7. doi: 10.1016/B978-0-444-62702-5.00007-X. PMID: 26564074
Grossman SA, Krabak MJ
Cancer Treat Rev 1999 Apr;25(2):103-19. doi: 10.1053/ctrv.1999.0119. PMID: 10395835

Clinical prediction guides

Ren C, Zhang W, Zhou A, Zhou J, Cheng H, Tang X, Fang F, Ren X
Pediatr Neurol 2023 Jun;143:96-99. Epub 2023 Mar 4 doi: 10.1016/j.pediatrneurol.2023.02.019. PMID: 37060644
Bahranifard B, Mehdizadeh S, Hamidi A, Khosravi A, Emami R, Mirzaei K, Nemati R, Nemati F, Assadi M, Gholamrezanezhad A
Neuroradiol J 2022 Feb;35(1):3-24. Epub 2021 Jul 5 doi: 10.1177/19714009211029177. PMID: 34224248Free PMC Article
Mormina E, Granata F, Vinci SL, Coglitore A, Caragliano AA, Tessitore A, Longo M, Visalli C
Curr Med Imaging 2021;17(12):1391-1402. doi: 10.2174/1573405617666210527091109. PMID: 34047260
Chiavazza C, Pellerino A, Ferrio F, Cistaro A, Soffietti R, Rudà R
Biomed Res Int 2018;2018:3606970. Epub 2018 Jun 21 doi: 10.1155/2018/3606970. PMID: 30035121Free PMC Article
Sohn M, Culver DA, Judson MA, Scott TF, Tavee J, Nozaki K
Am J Med Sci 2014 Mar;347(3):195-8. doi: 10.1097/MAJ.0b013e3182808781. PMID: 23364469

Recent systematic reviews

Toudou-Daouda M, Ibrahim-Mamadou AK
BMC Neurol 2022 Feb 4;22(1):44. doi: 10.1186/s12883-022-02569-6. PMID: 35120474Free PMC Article
Lewis A, Jain R, Frontera J, Placantonakis DG, Galetta S, Balcer L, Melmed KR
J Neuroimaging 2021 Sep;31(5):826-848. Epub 2021 Jun 8 doi: 10.1111/jon.12880. PMID: 34105198Free PMC Article

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