U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Monostotic fibrous dysplasia

MedGen UID:
42020
•Concept ID:
C0016064
•
Disease or Syndrome
Synonyms: Dysplasia, Monostotic Fibrous; Dysplasias, Monostotic Fibrous; Fibrous Dysplasia, Monostotic; Fibrous Dysplasias, Monostotic; Monostotic Fibrous Dysplasia; Monostotic Fibrous Dysplasias
SNOMED CT: Monostotic fibrous dysplasia (89859004); Localized osteitis fibrosa (89859004); Osteitis fibrosa circumscripta (89859004)
 
HPO: HP:0010736
Monarch Initiative: MONDO:0019665
Orphanet: ORPHA93277

Definition

Fibrous dysplasia of the bones were lesions are localized in only one bone. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMonostotic fibrous dysplasia
Follow this link to review classifications for Monostotic fibrous dysplasia in Orphanet.

Professional guidelines

PubMed

Surgical treatment of monostotic fibrous dysplasia of the temporal bone: a retrospective analysis.
Yang H, Chen S, Zheng Y, Xu Y, Zhang X, Xiong H, Zhang Z, Chen L
Am J Otolaryngol 2012 Nov-Dec;33(6):697-701. Epub 2012 Jul 13 doi: 10.1016/j.amjoto.2012.05.010. PMID: 22795233

Recent clinical studies

Etiology

Jawbone fibrous dysplasia: retrospective evaluation in a cases series surgically treated and short review of the literature.
Pacino GA, Cocuzza S, Tonoli G, Boscolo Rizzo P, Tirelli G, Tofanelli M, Ciprandi G, La Mantia I, Maniaci A, Da Mosto MC, Spinato G
Acta Biomed 2020 Oct 13;92(1):e2021018. doi: 10.23750/abm.v92i1.9904. PMID: 33682826Free PMC Article
Malignant transformation in monostotic fibrous dysplasia: clinical features, imaging features, outcomes in 10 patients, and review.
Qu N, Yao W, Cui X, Zhang H
Medicine (Baltimore) 2015 Jan;94(3):e369. doi: 10.1097/MD.0000000000000369. PMID: 25621678Free PMC Article
Clival fibrous dysplasia: Case series and review of the literature.
Heman-Ackah SE, Boyer H, Odland R
Ear Nose Throat J 2014 Dec;93(12):E4-9. doi: 10.1177/014556131409301202. PMID: 25531855
Monostotic fibrous dysplasia of the ribs.
Traibi A, El Oueriachi F, El Hammoumi M, Al Bouzidi A, Kabiri el H
Interact Cardiovasc Thorac Surg 2012 Jan;14(1):41-3. Epub 2011 Nov 16 doi: 10.1093/icvts/ivr048. PMID: 22108945Free PMC Article
Fibrous dysplasia.
Parekh SG, Donthineni-Rao R, Ricchetti E, Lackman RD
J Am Acad Orthop Surg 2004 Sep-Oct;12(5):305-13. doi: 10.5435/00124635-200409000-00005. PMID: 15469225

Diagnosis

Monostotic fibrous dysplasia at C7 treated with vertebroplasty: a case report and review of the literature.
Xin X, Feng J, Yue C, Jin T, Liu X
World J Surg Oncol 2019 Nov 9;17(1):186. doi: 10.1186/s12957-019-1717-2. PMID: 31706319Free PMC Article
Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature.
Basaran R, Kaksi M, Gur E, Efendioglu M, Balkuv E, Sav A
Pan Afr Med J 2014;19:124. Epub 2014 Oct 3 doi: 10.11604/pamj.2014.19.124.5203. PMID: 25745531Free PMC Article
Acromegaly and McCune-Albright syndrome.
Salenave S, Boyce AM, Collins MT, Chanson P
J Clin Endocrinol Metab 2014 Jun;99(6):1955-69. Epub 2014 Feb 11 doi: 10.1210/jc.2013-3826. PMID: 24517150Free PMC Article
Fibrous dysplasia.
Lietman SA, Levine MA
Pediatr Endocrinol Rev 2013 Jun;10 Suppl 2:389-96. PMID: 23858622
Fibrous dysplasia.
Williams DM, Thomas RS
J Laryngol Otol 1975 Apr;89(4):359-74. doi: 10.1017/s002221510008049x. PMID: 1127331

Therapy

Fibrous dysplasia.
Parekh SG, Donthineni-Rao R, Ricchetti E, Lackman RD
J Am Acad Orthop Surg 2004 Sep-Oct;12(5):305-13. doi: 10.5435/00124635-200409000-00005. PMID: 15469225
Treatment of monostotic fibrous dysplasia with pamidronate.
Kos M, Luczak K, Godzinski J, Klempous J
J Craniomaxillofac Surg 2004 Feb;32(1):10-5. doi: 10.1016/j.jcms.2003.07.009. PMID: 14729043
Craniomaxillofacial fibrous dysplasia.
Ozek C, Gundogan H, Bilkay U, Tokat C, Gurler T, Songur E
J Craniofac Surg 2002 May;13(3):382-9. doi: 10.1097/00001665-200205000-00004. PMID: 12040205
Monostotic fibrous dysplasia of the lumbar spine.
Avimadje AM, Goupille P, Zerkak D, Begnard G, Brunais-Besse J, Valat JP
Joint Bone Spine 2000 Jan;67(1):65-70. PMID: 10773971
Symptomatic monostotic fibrous dysplasia of the thoracic spine.
Oba M, Nakagami W, Maeda M, Kobayashi K
Spine (Phila Pa 1976) 1998 Mar 15;23(6):741-3. doi: 10.1097/00007632-199803150-00019. PMID: 9549798

Prognosis

Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia.
Rosario MS, Hayashi K, Yamamoto N, Takeuchi A, Miwa S, Taniguchi Y, Tsuchiya H
World J Surg Oncol 2017 Jan 5;15(1):1. doi: 10.1186/s12957-016-1068-1. PMID: 28057011Free PMC Article
Malignant transformation in monostotic fibrous dysplasia: clinical features, imaging features, outcomes in 10 patients, and review.
Qu N, Yao W, Cui X, Zhang H
Medicine (Baltimore) 2015 Jan;94(3):e369. doi: 10.1097/MD.0000000000000369. PMID: 25621678Free PMC Article
Monostotic fibrous dysplasia of the ribs.
Traibi A, El Oueriachi F, El Hammoumi M, Al Bouzidi A, Kabiri el H
Interact Cardiovasc Thorac Surg 2012 Jan;14(1):41-3. Epub 2011 Nov 16 doi: 10.1093/icvts/ivr048. PMID: 22108945Free PMC Article
Twenty-year follow-up of monostotic fibrous dysplasia of the second cervical vertebra: a case report and review of the literature.
Meredith DS, Healey JH
J Bone Joint Surg Am 2011 Jul 6;93(13):e74. doi: 10.2106/JBJS.J.01881. PMID: 21776559
Fibrous dysplasia.
Parekh SG, Donthineni-Rao R, Ricchetti E, Lackman RD
J Am Acad Orthop Surg 2004 Sep-Oct;12(5):305-13. doi: 10.5435/00124635-200409000-00005. PMID: 15469225

Clinical prediction guides

Radiographic Follow-Up of Fibrous Dysplasia in 138 Patients.
Hwang D, Jeon J, Hong SH, Yoo HJ, Choi JY, Chae HD
AJR Am J Roentgenol 2020 Dec;215(6):1430-1435. Epub 2020 Oct 14 doi: 10.2214/AJR.20.22978. PMID: 33052697
Monostotic fibrous dysplasia at C7 treated with vertebroplasty: a case report and review of the literature.
Xin X, Feng J, Yue C, Jin T, Liu X
World J Surg Oncol 2019 Nov 9;17(1):186. doi: 10.1186/s12957-019-1717-2. PMID: 31706319Free PMC Article
Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia.
Rosario MS, Hayashi K, Yamamoto N, Takeuchi A, Miwa S, Taniguchi Y, Tsuchiya H
World J Surg Oncol 2017 Jan 5;15(1):1. doi: 10.1186/s12957-016-1068-1. PMID: 28057011Free PMC Article
Acromegaly and McCune-Albright syndrome.
Salenave S, Boyce AM, Collins MT, Chanson P
J Clin Endocrinol Metab 2014 Jun;99(6):1955-69. Epub 2014 Feb 11 doi: 10.1210/jc.2013-3826. PMID: 24517150Free PMC Article
Fibrous dysplasia.
Lietman SA, Levine MA
Pediatr Endocrinol Rev 2013 Jun;10 Suppl 2:389-96. PMID: 23858622

Recent systematic reviews

Frequency of spontaneous osteosarcomatous transformation of craniofacial fibrous dysplasia: a systematic review.
Furmah P, Aminoshariae A, Mupparapu M, Syed AZ
Oral Surg Oral Med Oral Pathol Oral Radiol 2023 May;135(5):678-685. Epub 2022 Dec 24 doi: 10.1016/j.oooo.2022.12.007. PMID: 36828758
Prevalence of Different Forms and Involved Bones of Craniofacial Fibrous Dysplasia.
Yang L, Wu H, Lu J, Teng L
J Craniofac Surg 2017 Jan;28(1):21-25. doi: 10.1097/SCS.0000000000002830. PMID: 27922965

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...