U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dermatosis papulosa nigra

MedGen UID:
4238
•Concept ID:
C0011645
•
Disease or Syndrome
Synonym: Dermatosis Papulosa Nigra
SNOMED CT: Dermatosis papulosa nigra (103672009); Dermatosis papulosa nigra (254669003)
 
Monarch Initiative: MONDO:0007446
OMIM®: 125600

Definition

A benign skin condition commonly seen in dark-skinned individuals that is characterized by multiple small hyperpigmented papular lesions resembling seborrheic keratosis on the face and upper body. [from NCI]

Clinical features

From HPO
Abnormality of the skin
MedGen UID:
1845238
•Concept ID:
C5848159
•
Anatomical Abnormality
An abnormality of the skin.
See: Feature record | Search on this feature

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDermatosis papulosa nigra

Professional guidelines

PubMed

A Systematic Review on the Treatment of Dermatosis Papulosa Nigra.
Maghfour J, Ogunleye T
J Drugs Dermatol 2021 Apr 1;20(4):467-472. doi: 10.36849/JDD.2021.5555. PMID: 33852246
Elective Treatment of Dermatosis Papulosa Nigra: A Review of Treatment Modalities.
Tran M, Richer V
Skin Therapy Lett 2020 Sep;25(4):1-5. PMID: 33017107
What's new in objective assessment and treatment of facial hyperpigmentation?
Molinar VE, Taylor SC, Pandya AG
Dermatol Clin 2014 Apr;32(2):123-35. doi: 10.1016/j.det.2013.12.008. PMID: 24679999

Recent clinical studies

Etiology

Elective Treatment of Dermatosis Papulosa Nigra: A Review of Treatment Modalities.
Tran M, Richer V
Skin Therapy Lett 2020 Sep;25(4):1-5. PMID: 33017107
Dermatosis Papulosa Nigra and 10,600-nm CO2 laser, a good choice.
Bruscino N, Conti R, Campolmi P, Bonan P, Cannarozzo G, Lazzeri L, Moretti S
J Cosmet Laser Ther 2014 Jun;16(3):114-6. Epub 2013 Nov 18 doi: 10.3109/14764172.2013.854640. PMID: 24131098
FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra.
Hafner C, Landthaler M, Mentzel T, Vogt T
Br J Dermatol 2010 Mar;162(3):508-12. Epub 2009 Sep 1 doi: 10.1111/j.1365-2133.2009.09488.x. PMID: 19845664
Dermatosis papulosa nigra in Dakar, Senegal.
Niang SO, Kane A, Diallo M, Choutah F, Dieng MT, Ndiaye B
Int J Dermatol 2007 Oct;46 Suppl 1:45-7. doi: 10.1111/j.1365-4632.2007.03465.x. PMID: 17919208
Study of the skin disease spectrum occurring in an Afro-Caribbean population.
Dunwell P, Rose A
Int J Dermatol 2003 Apr;42(4):287-9. doi: 10.1046/j.1365-4362.2003.01358.x. PMID: 12694494

Diagnosis

The color of skin: black diseases of the skin, nails, and mucosa.
Qiu CC, Brown AE, Lobitz GR, Shanker A, Hsu S
Clin Dermatol 2019 Sep-Oct;37(5):447-467. Epub 2019 Aug 17 doi: 10.1016/j.clindermatol.2019.08.003. PMID: 31896402
Recent advances in managing and understanding seborrheic keratosis.
Wollina U
F1000Res 2019;8 Epub 2019 Aug 28 doi: 10.12688/f1000research.18983.1. PMID: 31508199Free PMC Article
What's new in objective assessment and treatment of facial hyperpigmentation?
Molinar VE, Taylor SC, Pandya AG
Dermatol Clin 2014 Apr;32(2):123-35. doi: 10.1016/j.det.2013.12.008. PMID: 24679999
Acquired hyperpigmentations.
Cestari TF, Dantas LP, Boza JC
An Bras Dermatol 2014 Jan-Feb;89(1):11-25. doi: 10.1590/abd1806-4841.20142353. PMID: 24626644Free PMC Article
Study of the skin disease spectrum occurring in an Afro-Caribbean population.
Dunwell P, Rose A
Int J Dermatol 2003 Apr;42(4):287-9. doi: 10.1046/j.1365-4362.2003.01358.x. PMID: 12694494

Therapy

Photodynamic therapy for facial dermatosis papulosa nigra: Efficacy and safety in a preliminary study.
Huang Z, Wang F, Liu D, Zhang R
Photodiagnosis Photodyn Ther 2024 Aug;48:104273. Epub 2024 Jul 11 doi: 10.1016/j.pdpdt.2024.104273. PMID: 39002830
A Systematic Review on the Treatment of Dermatosis Papulosa Nigra.
Maghfour J, Ogunleye T
J Drugs Dermatol 2021 Apr 1;20(4):467-472. doi: 10.36849/JDD.2021.5555. PMID: 33852246
Treatment of dermatosis papulosa nigra using a carbon dioxide laser.
Furukawa F, Mizawa M, Shimizu T
J Cosmet Dermatol 2020 Oct;19(10):2572-2575. Epub 2020 Jan 28 doi: 10.1111/jocd.13309. PMID: 31990432
What's new in objective assessment and treatment of facial hyperpigmentation?
Molinar VE, Taylor SC, Pandya AG
Dermatol Clin 2014 Apr;32(2):123-35. doi: 10.1016/j.det.2013.12.008. PMID: 24679999
Dermatosis Papulosa Nigra and 10,600-nm CO2 laser, a good choice.
Bruscino N, Conti R, Campolmi P, Bonan P, Cannarozzo G, Lazzeri L, Moretti S
J Cosmet Laser Ther 2014 Jun;16(3):114-6. Epub 2013 Nov 18 doi: 10.3109/14764172.2013.854640. PMID: 24131098

Prognosis

A Systematic Review on the Treatment of Dermatosis Papulosa Nigra.
Maghfour J, Ogunleye T
J Drugs Dermatol 2021 Apr 1;20(4):467-472. doi: 10.36849/JDD.2021.5555. PMID: 33852246
The color of skin: black diseases of the skin, nails, and mucosa.
Qiu CC, Brown AE, Lobitz GR, Shanker A, Hsu S
Clin Dermatol 2019 Sep-Oct;37(5):447-467. Epub 2019 Aug 17 doi: 10.1016/j.clindermatol.2019.08.003. PMID: 31896402
Clinical features and treatment of dermatosis papulosa nigra in migrants to Italy.
Calcaterra R, Franco G, Valenzano M, Fazio R, Morrone A
Skinmed 2010 Jul-Aug;8(4):207-9. PMID: 21137605
Study of the skin disease spectrum occurring in an Afro-Caribbean population.
Dunwell P, Rose A
Int J Dermatol 2003 Apr;42(4):287-9. doi: 10.1046/j.1365-4362.2003.01358.x. PMID: 12694494

Clinical prediction guides

Carbon dioxide laser ablation of dermatosis papulosa nigra: high satisfaction and few complications in patients with pigmented skin.
Ali FR, Bakkour W, Ferguson JE, Madan V
Lasers Med Sci 2016 Apr;31(3):593-5. Epub 2016 Feb 11 doi: 10.1007/s10103-016-1906-y. PMID: 26868030
Dermatosis Papulosa Nigra and 10,600-nm CO2 laser, a good choice.
Bruscino N, Conti R, Campolmi P, Bonan P, Cannarozzo G, Lazzeri L, Moretti S
J Cosmet Laser Ther 2014 Jun;16(3):114-6. Epub 2013 Nov 18 doi: 10.3109/14764172.2013.854640. PMID: 24131098
Clinical features and treatment of dermatosis papulosa nigra in migrants to Italy.
Calcaterra R, Franco G, Valenzano M, Fazio R, Morrone A
Skinmed 2010 Jul-Aug;8(4):207-9. PMID: 21137605
A randomized, double-blind comparison of two topical anesthetic formulations prior to electrodesiccation of dermatosis papulosa nigra.
Carter EL, Coppola CA, Barsanti FA
Dermatol Surg 2006 Jan;32(1):1-6. doi: 10.1111/1524-4725.2006.32000. PMID: 16393591

Recent systematic reviews

A Systematic Review on the Treatment of Dermatosis Papulosa Nigra.
Maghfour J, Ogunleye T
J Drugs Dermatol 2021 Apr 1;20(4):467-472. doi: 10.36849/JDD.2021.5555. PMID: 33852246

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...