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Herpes zoster

MedGen UID:
42437
Concept ID:
C0019360
Disease or Syndrome
Synonym: Shingles
SNOMED CT: Zoster (4740000); Herpes zoster infection (4740000); Herpes zoster (4740000); Shingles (4740000); Zona (4740000)
 
Monarch Initiative: MONDO:0005609

Definition

A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient''s initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Patil A, Goldust M, Wollina U
Viruses 2022 Jan 19;14(2) doi: 10.3390/v14020192. PMID: 35215786Free PMC Article
Cushing K, Higgins PDR
JAMA 2021 Jan 5;325(1):69-80. doi: 10.1001/jama.2020.18936. PMID: 33399844Free PMC Article
Saguil A, Kane S, Mercado M, Lauters R
Am Fam Physician 2017 Nov 15;96(10):656-663. PMID: 29431387

Curated

UK NICE Clinical Guideline CG173, Neuropathic pain in adults: pharmacological management in non-specialist settings, 2020

Recent clinical studies

Etiology

Cohen EJ, Jeng BH
Cornea 2021 Aug 1;40(8):943-949. doi: 10.1097/ICO.0000000000002754. PMID: 34029242Free PMC Article
Shah RA, Limmer AL, Nwannunu CE, Patel RR, Mui UN, Tyring SK
Skin Therapy Lett 2019 Jul;24(4):5-7. PMID: 31339679
Le P, Rothberg M
BMJ 2019 Jan 10;364:k5095. doi: 10.1136/bmj.k5095. PMID: 30630827
Saguil A, Kane S, Mercado M, Lauters R
Am Fam Physician 2017 Nov 15;96(10):656-663. PMID: 29431387
Wareham DW, Breuer J
BMJ 2007 Jun 9;334(7605):1211-5. doi: 10.1136/bmj.39206.571042.AE. PMID: 17556477Free PMC Article

Diagnosis

Narainswami N
S Afr Med J 2023 Aug 3;113(8):28-29. doi: 10.7196/SAMJ.2023.v113i8.649. PMID: 37882117
Hirade T, Koike D, Matama C, Yamada K, Kato F
Pediatr Int 2022 Jan;64(1):e15111. doi: 10.1111/ped.15111. PMID: 35831585
Zhang Y, Kong Y, Liu ZH
QJM 2022 Jun 7;115(6):402. doi: 10.1093/qjmed/hcac109. PMID: 35482516
Le P, Rothberg M
BMJ 2019 Jan 10;364:k5095. doi: 10.1136/bmj.k5095. PMID: 30630827
Schmader K
Ann Intern Med 2018 Aug 7;169(3):ITC19-ITC31. doi: 10.7326/AITC201808070. PMID: 30083718

Therapy

D'Haens G, Dubinsky M, Kobayashi T, Irving PM, Howaldt S, Pokrotnieks J, Krueger K, Laskowski J, Li X, Lissoos T, Milata J, Morris N, Arora V, Milch C, Sandborn W, Sands BE; LUCENT Study Group
N Engl J Med 2023 Jun 29;388(26):2444-2455. doi: 10.1056/NEJMoa2207940. PMID: 37379135
Loftus EV Jr, Panés J, Lacerda AP, Peyrin-Biroulet L, D'Haens G, Panaccione R, Reinisch W, Louis E, Chen M, Nakase H, Begun J, Boland BS, Phillips C, Mohamed MF, Liu J, Geng Z, Feng T, Dubcenco E, Colombel JF
N Engl J Med 2023 May 25;388(21):1966-1980. doi: 10.1056/NEJMoa2212728. PMID: 37224198
Callegaro A, Curran D, Matthews S
Pharm Stat 2020 Sep;19(5):636-645. Epub 2020 Mar 27 doi: 10.1002/pst.2020. PMID: 32220002Free PMC Article
Bolton L
Wounds 2018 May;30(5):144-146. PMID: 29847305
Abdel-Haq NM, Asmar BI
Indian J Pediatr 2001 Jul;68(7):649-54. doi: 10.1007/BF02752280. PMID: 11519289

Prognosis

Asada H
J Dermatol 2023 Mar;50(3):305-310. Epub 2022 Dec 20 doi: 10.1111/1346-8138.16666. PMID: 36539935
Gershon AA, Gershon MD, Shapiro ED
J Infect Dis 2021 Sep 30;224(12 Suppl 2):S387-S397. doi: 10.1093/infdis/jiaa573. PMID: 34590140Free PMC Article
Cohen EJ, Jeng BH
Cornea 2021 Aug 1;40(8):943-949. doi: 10.1097/ICO.0000000000002754. PMID: 34029242Free PMC Article
van Oorschot D, Vroling H, Bunge E, Diaz-Decaro J, Curran D, Yawn B
Hum Vaccin Immunother 2021 Jun 3;17(6):1714-1732. Epub 2021 Mar 2 doi: 10.1080/21645515.2020.1847582. PMID: 33651654Free PMC Article
Le P, Sabella C, Rothberg MB
Cleve Clin J Med 2017 May;84(5):359-366. doi: 10.3949/ccjm.84a.16020. PMID: 28530894

Clinical prediction guides

Petersen PT, Bodilsen J, Jepsen MPG, Larsen L, Storgaard M, Hansen BR, Lüttichau HR, Helweg-Larsen J, Wiese L, Andersen CØ, Nielsen H, Brandt CT; Danish Study Group of Infections of the Brain (DASGIB)
Infection 2024 Jun;52(3):839-846. Epub 2023 Nov 2 doi: 10.1007/s15010-023-02113-9. PMID: 37917395Free PMC Article
Nakano H, Fujiwara T, Tsujimoto Y, Morishima N, Kasahara T, Ameya M, Tachibana K, Sanada S, Toufukuji S, Hato N
Auris Nasus Larynx 2024 Feb;51(1):154-160. Epub 2023 May 4 doi: 10.1016/j.anl.2023.04.007. PMID: 37149416
Loftus EV Jr, Panés J, Lacerda AP, Peyrin-Biroulet L, D'Haens G, Panaccione R, Reinisch W, Louis E, Chen M, Nakase H, Begun J, Boland BS, Phillips C, Mohamed MF, Liu J, Geng Z, Feng T, Dubcenco E, Colombel JF
N Engl J Med 2023 May 25;388(21):1966-1980. doi: 10.1056/NEJMoa2212728. PMID: 37224198
van Dam CS, Lede I, Schaar J, Al-Dulaimy M, Rösken R, Smits M
Int J Infect Dis 2021 Oct;111:169-171. Epub 2021 Aug 21 doi: 10.1016/j.ijid.2021.08.048. PMID: 34428545Free PMC Article
Panatto D, Bragazzi NL, Rizzitelli E, Bonanni P, Boccalini S, Icardi G, Gasparini R, Amicizia D
Hum Vaccin Immunother 2015;11(1):245-62. doi: 10.4161/hv.36160. PMID: 25483704Free PMC Article

Recent systematic reviews

Nakano H, Fujiwara T, Tsujimoto Y, Morishima N, Kasahara T, Ameya M, Tachibana K, Sanada S, Toufukuji S, Hato N
Auris Nasus Larynx 2024 Feb;51(1):154-160. Epub 2023 May 4 doi: 10.1016/j.anl.2023.04.007. PMID: 37149416
Din S, Selinger CP, Black CJ, Ford AC
Aliment Pharmacol Ther 2023 Mar;57(6):666-675. Epub 2022 Dec 31 doi: 10.1111/apt.17379. PMID: 36585944
Kawai K, Yawn BP
Mayo Clin Proc 2017 Dec;92(12):1806-1821. doi: 10.1016/j.mayocp.2017.10.009. PMID: 29202939
Ahn KH, Park YJ, Hong SC, Lee EH, Lee JS, Oh MJ, Kim HJ
J Obstet Gynaecol 2016 Jul;36(5):563-6. Epub 2016 Mar 10 doi: 10.3109/01443615.2015.1127905. PMID: 26965725
Kawai K, Gebremeskel BG, Acosta CJ
BMJ Open 2014 Jun 10;4(6):e004833. doi: 10.1136/bmjopen-2014-004833. PMID: 24916088Free PMC Article

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    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG173, Neuropathic pain in adults: pharmacological management in non-specialist settings, 2020

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