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Anterior scalloping of vertebral bodies

MedGen UID:
435977
Concept ID:
C2673652
Finding
Synonym: Anterior scalloping vertebral bodies
 
HPO: HP:0004580

Definition

An excessive concavity of the anterior surface of one or more vertebral bodies. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior scalloping of vertebral bodies

Conditions with this feature

Spondyloepiphyseal dysplasia, Cantu type
MedGen UID:
435975
Concept ID:
C2673649
Disease or Syndrome
An extremely rare type of spondyloepiphyseal dysplasia described in about 5 patients to date with clinical signs including short stature, peculiar facies with blepharophimosis, upward slanted eyes, abundant eyebrows and eyelashes, coarse voice, and short hands and feet.

Recent clinical studies

Etiology

Lundby R, Rand-Hendriksen S, Hald JK, Lilleås FG, Pripp AH, Skaar S, Paus B, Geiran O, Smith HJ
AJNR Am J Neuroradiol 2009 Sep;30(8):1534-40. Epub 2009 May 20 doi: 10.3174/ajnr.A1620. PMID: 19461064Free PMC Article

Diagnosis

Arici V, Rossi M, Bozzani A, Moia A, Odero A
Spine (Phila Pa 1976) 2012 Dec 15;37(26):E1665-71. doi: 10.1097/BRS.0b013e318273dc66. PMID: 22990367
Lundby R, Rand-Hendriksen S, Hald JK, Lilleås FG, Pripp AH, Skaar S, Paus B, Geiran O, Smith HJ
AJNR Am J Neuroradiol 2009 Sep;30(8):1534-40. Epub 2009 May 20 doi: 10.3174/ajnr.A1620. PMID: 19461064Free PMC Article
Perera NR, Senevirathna LN, de Alwis DS, Perera SS
Ceylon Med J 2006 Dec;51(4):148-9. doi: 10.4038/cmj.v51i4.1146. PMID: 17461326
Singrakhia MD, Parmar H, Maheshwari M, Fehlings M
Surg Neurol 2006 Aug;66(2):192-6; discussion 196. doi: 10.1016/j.surneu.2005.11.057. PMID: 16876626

Prognosis

Lundby R, Rand-Hendriksen S, Hald JK, Lilleås FG, Pripp AH, Skaar S, Paus B, Geiran O, Smith HJ
AJNR Am J Neuroradiol 2009 Sep;30(8):1534-40. Epub 2009 May 20 doi: 10.3174/ajnr.A1620. PMID: 19461064Free PMC Article

Clinical prediction guides

Smithson SF, Grier D, Hall CM
Clin Dysmorphol 2009 Jan;18(1):31-35. doi: 10.1097/MCD.0b013e3283189762. PMID: 19050402

Recent systematic reviews

Arici V, Rossi M, Bozzani A, Moia A, Odero A
Spine (Phila Pa 1976) 2012 Dec 15;37(26):E1665-71. doi: 10.1097/BRS.0b013e318273dc66. PMID: 22990367

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