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Intertrigo

MedGen UID:
43928
•Concept ID:
C0021807
•
Disease or Syndrome
Synonyms: Eczema intertrigo; Erythema intertrigo; Intertriginous dermatitis; intertrigo
SNOMED CT: Intertriginous dermatitis (58759008); Intertrigo (58759008); Erythema intertrigo (58759008); Eczema intertrigo (58759008)
 
Monarch Initiative: MONDO:0021340

Definition

A type of superficial inflammatory dermatitis occurring where two skin surfaces are in apposition. Intertrigo occurs in the skin fold and results from friction, heat, moisture and may lead to skin infection. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntertrigo

Professional guidelines

PubMed

Moisture-associated skin damage (MASD): A best practice recommendation from Wund-D.A.CH.
Dissemond J, Assenheimer B, Gerber V, Hintner M, Puntigam MJ, Kolbig N, Koller S, Kurz P, Läuchli S, Probst S, Protz K, Steiniger A, Strohal R, Traber J, Kottner J
J Dtsch Dermatol Ges 2021 Jun;19(6):815-825. Epub 2021 May 4 doi: 10.1111/ddg.14388. PMID: 33942514
Pressure and Friction Injuries in Primary Care.
Phillips S, Seiverling E, Silvis M
Prim Care 2015 Dec;42(4):631-44. Epub 2015 Oct 14 doi: 10.1016/j.pop.2015.07.002. PMID: 26612376
Management of cutaneous erythrasma.
Holdiness MR
Drugs 2002;62(8):1131-41. doi: 10.2165/00003495-200262080-00002. PMID: 12010076

Recent clinical studies

Etiology

Maintaining skin integrity in the aged: A systematic review.
Lichterfeld-Kottner A, El Genedy M, Lahmann N, Blume-Peytavi U, Büscher A, Kottner J
Int J Nurs Stud 2020 Mar;103:103509. Epub 2019 Dec 23 doi: 10.1016/j.ijnurstu.2019.103509. PMID: 31945604
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Fungal infections of the folds (intertriginous areas).
Metin A, Dilek N, Demirseven DD
Clin Dermatol 2015 Jul-Aug;33(4):437-47. Epub 2015 Apr 7 doi: 10.1016/j.clindermatol.2015.04.005. PMID: 26051058
Improving the management of seborrhoeic dermatitis.
Ooi ET, Tidman MJ
Practitioner 2014 Feb;258(1768):23-6, 3. PMID: 24689165

Diagnosis

Annular infectious dermatoses.
Liu WT, Sun PL, Bramono K, Ezmerli M, Yang CC, Chen W
Clin Dermatol 2022 Sep-Oct;40(5):427-440. Epub 2021 Dec 31 doi: 10.1016/j.clindermatol.2021.12.006. PMID: 34974106
Moisture-associated skin damage (MASD): A best practice recommendation from Wund-D.A.CH.
Dissemond J, Assenheimer B, Gerber V, Hintner M, Puntigam MJ, Kolbig N, Koller S, Kurz P, Läuchli S, Probst S, Protz K, Steiniger A, Strohal R, Traber J, Kottner J
J Dtsch Dermatol Ges 2021 Jun;19(6):815-825. Epub 2021 May 4 doi: 10.1111/ddg.14388. PMID: 33942514
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Intertriginous eruption.
Wolf R, Oumeish OY, Parish LC
Clin Dermatol 2011 Mar-Apr;29(2):173-9. doi: 10.1016/j.clindermatol.2010.09.009. PMID: 21396557
Cutaneous trichosporosis.
Kamalam A, Senthamilselvi G, Ajithadas K, Thambiah AS
Mycopathologia 1988 Mar;101(3):167-75. doi: 10.1007/BF00437035. PMID: 3380135

Therapy

Maintaining skin integrity in the aged: A systematic review.
Lichterfeld-Kottner A, El Genedy M, Lahmann N, Blume-Peytavi U, Büscher A, Kottner J
Int J Nurs Stud 2020 Mar;103:103509. Epub 2019 Dec 23 doi: 10.1016/j.ijnurstu.2019.103509. PMID: 31945604
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
Malignant intertrigo.
Liu C, Ko MJ
CMAJ 2018 May 14;190(19):E595. doi: 10.1503/cmaj.180078. PMID: 29759966Free PMC Article
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Cutaneous trichosporosis.
Kamalam A, Senthamilselvi G, Ajithadas K, Thambiah AS
Mycopathologia 1988 Mar;101(3):167-75. doi: 10.1007/BF00437035. PMID: 3380135

Prognosis

Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses.
Semkova K, Gergovska M, Kazandjieva J, Tsankov N
Clin Dermatol 2015 Jul-Aug;33(4):483-91. Epub 2015 Apr 8 doi: 10.1016/j.clindermatol.2015.04.013. PMID: 26051066
Diaper (napkin) dermatitis: A fold (intertriginous) dermatosis.
Tüzün Y, Wolf R, Bağlam S, Engin B
Clin Dermatol 2015 Jul-Aug;33(4):477-82. Epub 2015 Apr 9 doi: 10.1016/j.clindermatol.2015.04.012. PMID: 26051065
Darier disease: A fold (intertriginous) dermatosis.
Engin B, Kutlubay Z, Erkan E, Tüzün Y
Clin Dermatol 2015 Jul-Aug;33(4):448-51. Epub 2015 Apr 9 doi: 10.1016/j.clindermatol.2015.04.009. PMID: 26051059
Fungal infections of the folds (intertriginous areas).
Metin A, Dilek N, Demirseven DD
Clin Dermatol 2015 Jul-Aug;33(4):437-47. Epub 2015 Apr 7 doi: 10.1016/j.clindermatol.2015.04.005. PMID: 26051058
Improving the management of seborrhoeic dermatitis.
Ooi ET, Tidman MJ
Practitioner 2014 Feb;258(1768):23-6, 3. PMID: 24689165

Clinical prediction guides

Perialar intertrigo in children and adolescents: A multicenter prospective study of 41 cases.
Sanchez A, Mahe E, Miquel J, Abasq C, Phan A, Mazereeuw-Hautier J, Lemille J, Maruani A, Bonniaud B, Plantin P, Mallet S, Martin H, Hubiche T, Chiaverini C, Lacour JP; Groupe de Recherche de la Société Française de Dermatologie Pédiatrique
Pediatr Dermatol 2022 Sep;39(5):702-707. Epub 2022 Jun 14 doi: 10.1111/pde.15036. PMID: 35699273Free PMC Article
Skin areas, clinical severity, duration and risk factors of intertrigo: A secondary data analysis.
Everink IHJ, Kottner J, van Haastregt JCM, Halfens R, Schols JMGA
J Tissue Viability 2021 Feb;30(1):102-107. Epub 2020 Dec 29 doi: 10.1016/j.jtv.2020.12.005. PMID: 33431261
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Diaper (napkin) dermatitis: A fold (intertriginous) dermatosis.
Tüzün Y, Wolf R, Bağlam S, Engin B
Clin Dermatol 2015 Jul-Aug;33(4):477-82. Epub 2015 Apr 9 doi: 10.1016/j.clindermatol.2015.04.012. PMID: 26051065
Intertriginous eruption.
Wolf R, Oumeish OY, Parish LC
Clin Dermatol 2011 Mar-Apr;29(2):173-9. doi: 10.1016/j.clindermatol.2010.09.009. PMID: 21396557

Recent systematic reviews

Maintaining skin integrity in the aged: A systematic review.
Lichterfeld-Kottner A, El Genedy M, Lahmann N, Blume-Peytavi U, Büscher A, Kottner J
Int J Nurs Stud 2020 Mar;103:103509. Epub 2019 Dec 23 doi: 10.1016/j.ijnurstu.2019.103509. PMID: 31945604
Risk factors and complications of lower limb cellulitis in Africa: a systematic review.
Tianyi FL, Mbanga CM, Danwang C, Agbor VN
BMJ Open 2018 Jul 23;8(7):e021175. doi: 10.1136/bmjopen-2017-021175. PMID: 30037869Free PMC Article
Risk factors for nonpurulent leg cellulitis: a systematic review and meta-analysis.
Quirke M, Ayoub F, McCabe A, Boland F, Smith B, O'Sullivan R, Wakai A
Br J Dermatol 2017 Aug;177(2):382-394. Epub 2017 Jul 25 doi: 10.1111/bjd.15186. PMID: 27864837
Systematic mapping review about costs and economic evaluations of skin conditions and diseases in the aged.
Lichterfeld-Kottner A, Hahnel E, Blume-Peytavi U, Kottner J
J Tissue Viability 2017 Feb;26(1):6-19. Epub 2016 Jul 25 doi: 10.1016/j.jtv.2016.07.002. PMID: 27544020
Preventing and treating intertrigo in the large skin folds of adults: a literature overview.
Mistiaen P, Poot E, Hickox S, Jochems C, Wagner C
Dermatol Nurs 2004 Feb;16(1):43-6, 49-57. PMID: 15022504

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