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Pre-B Acute Lymphoblastic Leukemia

MedGen UID:
44126
Concept ID:
C0023485
Neoplastic Process
Synonyms: Leukemia, Pre B Cell; Leukemia, Pre-B-Cell; Leukemias, Pre-B-Cell; Pre B ALL; Pre B Cell Leukemia; Pre B-ALL; Pre-B ALL; Pre-B-Cell Leukemia; Pre-B-Cell Leukemias; Precursor B Cell Lymphoblastic Leukemia; Precursor B Cell Lymphoblastic Leukemia Lymphoma; Precursor B Cell Lymphoblastic Lymphoma; Precursor B-Cell Lymphoblastic Leukemia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor B-Cell Lymphoblastic Lymphoma

Definition

An acute lymphoblastic leukemia that originates from pre-B lymphocytes. The pre-B lymphoblasts contain cytoplasmic immunoglobulin. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

McElroy S, Myers GD, Flatt T
J Pediatr Hematol Oncol 2023 May 1;45(4):e518-e521. Epub 2023 Jan 10 doi: 10.1097/MPH.0000000000002613. PMID: 36706304
Blaeschke F, Stenger D, Kaeuferle T, Willier S, Lotfi R, Kaiser AD, Assenmacher M, Döring M, Feucht J, Feuchtinger T
Cancer Immunol Immunother 2018 Jul;67(7):1053-1066. Epub 2018 Mar 31 doi: 10.1007/s00262-018-2155-7. PMID: 29605883Free PMC Article
Fei F, Lim M, Schmidhuber S, Moll J, Groffen J, Heisterkamp N
Mol Cancer 2012 Jun 21;11:42. doi: 10.1186/1476-4598-11-42. PMID: 22721004Free PMC Article

Recent clinical studies

Etiology

Hosein Pour Feizi A, Zeinali S, Toporski J, Sheervalilou R, Mehranfar S
Asian Pac J Cancer Prev 2020 Dec 1;21(12):3493-3500. doi: 10.31557/APJCP.2020.21.12.3493. PMID: 33369444Free PMC Article
Amjad A, Wali RM, Anjum S, Mansoor R
J Coll Physicians Surg Pak 2019 Jun;29(6):549-552. doi: 10.29271/jcpsp.2019.06.549. PMID: 31133155
Rezazadeh D, Moradi MT, Kazemi A, Mansouri K
Int J Lab Hematol 2015 Aug;37(4):530-5. Epub 2015 Feb 27 doi: 10.1111/ijlh.12332. PMID: 25726706
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article
Williams MT, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, Chapman KE, McAndrew R, Thomas A, Spence A, Gibson B, Graham GJ, Halsey C
Blood 2014 May 15;123(20):3116-27. Epub 2014 Apr 3 doi: 10.1182/blood-2013-05-499970. PMID: 24700781

Diagnosis

Diwan A, Barsode S
J Assoc Physicians India 2024 Mar;72(3):97-99. doi: 10.59556/japi.72.0446. PMID: 38736127
Zhu H, Ma H, Dong N, Wu M, Li D, Liu L, Shi Q, Ju X
BMC Cancer 2023 Feb 6;23(1):122. doi: 10.1186/s12885-023-10589-9. PMID: 36747147Free PMC Article
Martínez-Anaya D, Moreno-Lorenzana D, Reyes-León A, Juárez-Figueroa U, Dean M, Aguilar-Hernández MM, Rivera-Sánchez N, García-Islas J, Vieyra-Fuentes V, Zapata-Tarrés M, Juárez-Villegas L, Paredes-Aguilera R, Vega-Vega L, Rivera-Luna R, Juárez-Velázquez MDR, Pérez-Vera P
Int J Mol Sci 2022 Aug 24;23(17) doi: 10.3390/ijms23179587. PMID: 36076986Free PMC Article
Amjad A, Wali RM, Anjum S, Mansoor R
J Coll Physicians Surg Pak 2019 Jun;29(6):549-552. doi: 10.29271/jcpsp.2019.06.549. PMID: 31133155
Rezazadeh D, Moradi MT, Kazemi A, Mansouri K
Int J Lab Hematol 2015 Aug;37(4):530-5. Epub 2015 Feb 27 doi: 10.1111/ijlh.12332. PMID: 25726706

Therapy

Kantarjian H, Haddad FG, Jain N, Sasaki K, Short NJ, Loghavi S, Kanagal-Shamanna R, Jorgensen J, Khouri I, Kebriaei P, Alvarado Y, Kadia T, Paul S, Garcia-Manero G, Dabaja B, Yilmaz M, Jacob J, Garris R, O'Brien S, Ravandi F, Jabbour E
J Hematol Oncol 2023 May 2;16(1):44. doi: 10.1186/s13045-023-01444-2. PMID: 37131217Free PMC Article
Amjad A, Wali RM, Anjum S, Mansoor R
J Coll Physicians Surg Pak 2019 Jun;29(6):549-552. doi: 10.29271/jcpsp.2019.06.549. PMID: 31133155
Kobold S, Duewell P, Schnurr M, Subklewe M, Rothenfusser S, Endres S
Dtsch Arztebl Int 2015 Nov 27;112(48):809-15. doi: 10.3238/arztebl.2015.0809. PMID: 26667979Free PMC Article
Afsar FS, Ozek G, Vergin C
Cutan Ocul Toxicol 2015;34(4):350-1. Epub 2015 Jan 19 doi: 10.3109/15569527.2014.999861. PMID: 25597374
Safa M, Tavasoli B, Manafi R, Kiani F, Kashiri M, Ebrahimi S, Kazemi A
Tumour Biol 2015 May;36(5):3919-30. Epub 2015 Jan 15 doi: 10.1007/s13277-014-3035-1. PMID: 25589462

Prognosis

Kantarjian H, Haddad FG, Jain N, Sasaki K, Short NJ, Loghavi S, Kanagal-Shamanna R, Jorgensen J, Khouri I, Kebriaei P, Alvarado Y, Kadia T, Paul S, Garcia-Manero G, Dabaja B, Yilmaz M, Jacob J, Garris R, O'Brien S, Ravandi F, Jabbour E
J Hematol Oncol 2023 May 2;16(1):44. doi: 10.1186/s13045-023-01444-2. PMID: 37131217Free PMC Article
Amjad A, Wali RM, Anjum S, Mansoor R
J Coll Physicians Surg Pak 2019 Jun;29(6):549-552. doi: 10.29271/jcpsp.2019.06.549. PMID: 31133155
Georgakopoulos N, Diamantopoulos P, Micci F, Giannakopoulou N, Zervakis K, Dimitrakopoulou A, Viniou NA
In Vivo 2018 Sep-Oct;32(5):1241-1245. doi: 10.21873/invivo.11371. PMID: 30150451Free PMC Article
Kobold S, Duewell P, Schnurr M, Subklewe M, Rothenfusser S, Endres S
Dtsch Arztebl Int 2015 Nov 27;112(48):809-15. doi: 10.3238/arztebl.2015.0809. PMID: 26667979Free PMC Article
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article

Clinical prediction guides

Kurata M, Onishi I, Takahara T, Yamazaki Y, Ishibashi S, Goitsuka R, Kitamura D, Takita J, Hayashi Y, Largaesapda DA, Kitagawa M, Nakamura T
Cancer Sci 2021 Dec;112(12):4920-4930. Epub 2021 Oct 23 doi: 10.1111/cas.15164. PMID: 34653294Free PMC Article
Amjad A, Wali RM, Anjum S, Mansoor R
J Coll Physicians Surg Pak 2019 Jun;29(6):549-552. doi: 10.29271/jcpsp.2019.06.549. PMID: 31133155
Yamamoto K, Kawamoto S, Mizutani Y, Yakushijin K, Yamashita T, Nakamachi Y, Kawano S, Hayashi Y, Matsuoka H, Minami H
Cytogenet Genome Res 2016;149(3):165-170. Epub 2016 Sep 9 doi: 10.1159/000448447. PMID: 27607436
Kobold S, Duewell P, Schnurr M, Subklewe M, Rothenfusser S, Endres S
Dtsch Arztebl Int 2015 Nov 27;112(48):809-15. doi: 10.3238/arztebl.2015.0809. PMID: 26667979Free PMC Article
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article

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