U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mallory-Weiss syndrome

MedGen UID:
44265
•Concept ID:
C0024633
•
Disease or Syndrome
Synonyms: Gastroesophageal laceration-hemorrhage; Mallory-Weiss laceration; Mallory-Weiss tear; Mucosal lacerations - gastroesophageal junction
SNOMED CT: Gastro-esophageal laceration-hemorrhage syndrome (35265002); Mallory-Weiss tear (307131005); Mallory-Weiss syndrome (35265002); Gastroesophageal laceration-hemorrhage syndrome (35265002)
 
HPO: HP:0032062
Monarch Initiative: MONDO:0043247

Definition

Vomiting-induced mucosal laceration at the esophago-gastric junction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMallory-Weiss syndrome

Professional guidelines

PubMed

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Evaluation and management of diseases of the esophagus.
Meyer GW, Castell DO
Am J Otolaryngol 1981 Nov;2(4):336-44. doi: 10.1016/s0196-0709(81)80043-9. PMID: 7034570

Recent clinical studies

Etiology

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Overview of Mallory-Weiss syndrome.
Rich K
J Vasc Nurs 2018 Jun;36(2):91-93. doi: 10.1016/j.jvn.2018.04.001. PMID: 29747789
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Mallory-Weiss syndrome: clinical and endoscopic characteristics.
Yin A, Li Y, Jiang Y, Liu J, Luo H
Eur J Intern Med 2012 Jun;23(4):e92-6. Epub 2012 Mar 4 doi: 10.1016/j.ejim.2012.02.005. PMID: 22560400
The Mallory-Weiss syndrome.
Pagel J, Lindkear-Jensen S, Nielsen OV
Acta Chir Scand 1975;141(6):532-5. PMID: 1189860

Diagnosis

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Overview of Mallory-Weiss syndrome.
Rich K
J Vasc Nurs 2018 Jun;36(2):91-93. doi: 10.1016/j.jvn.2018.04.001. PMID: 29747789
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
The Mallory-Weiss syndrome.
St John DJ, Masterton JP, Yeomans ND, Dudley HA
Br Med J 1974 Jan 26;1(5899):140-3. doi: 10.1136/bmj.1.5899.140. PMID: 4544226Free PMC Article
Mallory-Weiss syndrome.
Weaver DH, Maxwell JG, Castleton KB
Am J Surg 1969 Dec;118(6):887-92. doi: 10.1016/0002-9610(69)90252-9. PMID: 5358896

Therapy

Mallory-Weiss syndrome in four hemodialysis patients: a case study.
Shi SS, Yang XZ, Zhang XY, Huang L, Guo HD, Li SF, Zhang W, Zhang YQ
BMC Nephrol 2023 Jun 27;24(1):188. doi: 10.1186/s12882-023-03250-x. PMID: 37365498Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Characterization of the syndrome of UGI bleeding from a Mallory-Weiss tear associated with transesophageal echocardiography.
Cappell MS, Dass K, Manickam P
Dig Dis Sci 2014 Oct;59(10):2381-9. Epub 2014 May 18 doi: 10.1007/s10620-014-3195-2. PMID: 24838497
Ulcers and nonvariceal bleeding.
Church NI, Palmer KR
Endoscopy 2003 Jan;35(1):22-6. doi: 10.1055/s-2003-36411. PMID: 12510222

Prognosis

Mallory-Weiss syndrome in four hemodialysis patients: a case study.
Shi SS, Yang XZ, Zhang XY, Huang L, Guo HD, Li SF, Zhang W, Zhang YQ
BMC Nephrol 2023 Jun 27;24(1):188. doi: 10.1186/s12882-023-03250-x. PMID: 37365498Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification.
Lee S, Ahn JY, Jung HY, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Kim JH, Kim SO
J Dig Dis 2016 Oct;17(10):676-684. doi: 10.1111/1751-2980.12409. PMID: 27624697
Ulcers and nonvariceal bleeding.
Church NI, Palmer KR
Endoscopy 2003 Jan;35(1):22-6. doi: 10.1055/s-2003-36411. PMID: 12510222
Mallory-Weiss syndrome in children.
Bak-Romaniszyn L, Małecka-Panas E, Czkwianianc E, Płaneta-Małecka I
Dis Esophagus 1999;12(1):65-7. doi: 10.1046/j.1442-2050.1999.00006.x. PMID: 10941865

Clinical prediction guides

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
The prediction value of scoring systems in Mallory-Weiss syndrome patients.
He L, Li ZB, Zhu HD, Wu XL, Tian DA, Li PY
Medicine (Baltimore) 2019 May;98(22):e15751. doi: 10.1097/MD.0000000000015751. PMID: 31145291Free PMC Article
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification.
Lee S, Ahn JY, Jung HY, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Kim JH, Kim SO
J Dig Dis 2016 Oct;17(10):676-684. doi: 10.1111/1751-2980.12409. PMID: 27624697
Ulcers and nonvariceal bleeding.
Church NI, Palmer KR
Endoscopy 2003 Jan;35(1):22-6. doi: 10.1055/s-2003-36411. PMID: 12510222
Frequency, significance and therapy of the Mallory-Weiss syndrome in patients with portal hypertension.
Paquet KJ, Mercado-Diaz M, Kalk JF
Hepatology 1990 May;11(5):879-83. doi: 10.1002/hep.1840110525. PMID: 2347558

Recent systematic reviews

Endoscopic clipping for acute nonvariceal upper-GI bleeding: a meta-analysis and critical appraisal of randomized controlled trials.
Yuan Y, Wang C, Hunt RH
Gastrointest Endosc 2008 Aug;68(2):339-51. doi: 10.1016/j.gie.2008.03.1122. PMID: 18656600

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...