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Mallory-Weiss syndrome

MedGen UID:
44265
•Concept ID:
C0024633
•
Disease or Syndrome
Synonyms: Gastroesophageal laceration-hemorrhage; Mallory-Weiss laceration; Mallory-Weiss tear; Mucosal lacerations - gastroesophageal junction
SNOMED CT: Gastro-esophageal laceration-hemorrhage syndrome (35265002); Mallory-Weiss tear (307131005); Mallory-Weiss syndrome (35265002); Gastroesophageal laceration-hemorrhage syndrome (35265002)
 
HPO: HP:0032062
Monarch Initiative: MONDO:0043247

Definition

Vomiting-induced mucosal laceration at the esophago-gastric junction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMallory-Weiss syndrome

Professional guidelines

PubMed

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Evaluation and management of diseases of the esophagus.
Meyer GW, Castell DO
Am J Otolaryngol 1981 Nov;2(4):336-44. doi: 10.1016/s0196-0709(81)80043-9. PMID: 7034570

Recent clinical studies

Etiology

Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Overview of Mallory-Weiss syndrome.
Rich K
J Vasc Nurs 2018 Jun;36(2):91-93. doi: 10.1016/j.jvn.2018.04.001. PMID: 29747789
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Mallory-Weiss syndrome: clinical and endoscopic characteristics.
Yin A, Li Y, Jiang Y, Liu J, Luo H
Eur J Intern Med 2012 Jun;23(4):e92-6. Epub 2012 Mar 4 doi: 10.1016/j.ejim.2012.02.005. PMID: 22560400
The Mallory-Weiss syndrome.
Pagel J, Lindkear-Jensen S, Nielsen OV
Acta Chir Scand 1975;141(6):532-5. PMID: 1189860

Diagnosis

Mallory-Weiss Syndrome.
Hu Z, Liu D
N Engl J Med 2024 May 30;390(20):e49. doi: 10.1056/NEJMicm2310882. PMID: 38810187
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Mallory-Weiss syndrome.
Carlson DS, Pfadt E
Nursing 2011 Oct;41(10):72. doi: 10.1097/01.NURSE.0000405123.46887.12. PMID: 21918419
Mallory-Weiss syndrome.
Weaver DH, Maxwell JG, Castleton KB
Am J Surg 1969 Dec;118(6):887-92. doi: 10.1016/0002-9610(69)90252-9. PMID: 5358896

Therapy

Mallory-Weiss Syndrome.
Hu Z, Liu D
N Engl J Med 2024 May 30;390(20):e49. doi: 10.1056/NEJMicm2310882. PMID: 38810187
Mallory-Weiss syndrome in four hemodialysis patients: a case study.
Shi SS, Yang XZ, Zhang XY, Huang L, Guo HD, Li SF, Zhang W, Zhang YQ
BMC Nephrol 2023 Jun 27;24(1):188. doi: 10.1186/s12882-023-03250-x. PMID: 37365498Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Evaluation and management of Non-variceal upper gastrointestinal bleeding.
Samuel R, Bilal M, Tayyem O, Guturu P
Dis Mon 2018 Jul;64(7):333-343. Epub 2018 Mar 7 doi: 10.1016/j.disamonth.2018.02.003. PMID: 29525375
Characterization of the syndrome of UGI bleeding from a Mallory-Weiss tear associated with transesophageal echocardiography.
Cappell MS, Dass K, Manickam P
Dig Dis Sci 2014 Oct;59(10):2381-9. Epub 2014 May 18 doi: 10.1007/s10620-014-3195-2. PMID: 24838497

Prognosis

Mallory-Weiss syndrome in four hemodialysis patients: a case study.
Shi SS, Yang XZ, Zhang XY, Huang L, Guo HD, Li SF, Zhang W, Zhang YQ
BMC Nephrol 2023 Jun 27;24(1):188. doi: 10.1186/s12882-023-03250-x. PMID: 37365498Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification.
Lee S, Ahn JY, Jung HY, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Kim JH, Kim SO
J Dig Dis 2016 Oct;17(10):676-684. doi: 10.1111/1751-2980.12409. PMID: 27624697
Ulcers and nonvariceal bleeding.
Church NI, Palmer KR
Endoscopy 2003 Jan;35(1):22-6. doi: 10.1055/s-2003-36411. PMID: 12510222
Mallory-Weiss syndrome in children.
Bak-Romaniszyn L, Małecka-Panas E, Czkwianianc E, Płaneta-Małecka I
Dis Esophagus 1999;12(1):65-7. doi: 10.1046/j.1442-2050.1999.00006.x. PMID: 10941865

Clinical prediction guides

A Systematic Analysis of Incidence, Therapeutic Strategies, and In-hospital Mortality of Mallory-Weiss Syndrome in Germany.
Mertens A, Essing T, Roderburg C, Luedde T, Kandler J, Loosen SH
J Clin Gastroenterol 2024 Aug 1;58(7):640-649. doi: 10.1097/MCG.0000000000001918. PMID: 37668412
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
The prediction value of scoring systems in Mallory-Weiss syndrome patients.
He L, Li ZB, Zhu HD, Wu XL, Tian DA, Li PY
Medicine (Baltimore) 2019 May;98(22):e15751. doi: 10.1097/MD.0000000000015751. PMID: 31145291Free PMC Article
Effective endoscopic treatment of Mallory-Weiss syndrome using Glasgow-Blatchford score and Forrest classification.
Lee S, Ahn JY, Jung HY, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Kim JH, Kim SO
J Dig Dis 2016 Oct;17(10):676-684. doi: 10.1111/1751-2980.12409. PMID: 27624697
Ulcers and nonvariceal bleeding.
Church NI, Palmer KR
Endoscopy 2003 Jan;35(1):22-6. doi: 10.1055/s-2003-36411. PMID: 12510222

Recent systematic reviews

Endoscopic clipping for acute nonvariceal upper-GI bleeding: a meta-analysis and critical appraisal of randomized controlled trials.
Yuan Y, Wang C, Hunt RH
Gastrointest Endosc 2008 Aug;68(2):339-51. doi: 10.1016/j.gie.2008.03.1122. PMID: 18656600

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