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Laryngeal cyst

MedGen UID:
451040
•Concept ID:
C0339880
•
Disease or Syndrome; Finding
Synonyms: congenital laryngeal cyst; Congenital laryngeal cyst; Cyst of larynx
SNOMED CT: Cyst of larynx (195867000)
 
HPO: HP:0100640
Monarch Initiative: MONDO:0015396
Orphanet: ORPHA141124

Definition

Presence of a cyst (sac-like structure) located in the larynx. [from HPO]

Professional guidelines

PubMed

Proposal for the surgical management of children with laryngeal saccular Cysts: A case series.
Rosas A, McCrary HC, Meier JD, Muntz HR, Park AH
Int J Pediatr Otorhinolaryngol 2019 Nov;126:109604. Epub 2019 Jul 26 doi: 10.1016/j.ijporl.2019.109604. PMID: 31369973
Laryngeal Cysts in Adults: Simplifying Classification and Management.
Heyes R, Lott DG
Otolaryngol Head Neck Surg 2017 Dec;157(6):928-939. Epub 2017 Jul 11 doi: 10.1177/0194599817715613. PMID: 28695764
Congenital laryngeal cyst: benefits of prenatal diagnosis and multidisciplinary perinatal management.
Busuttil M, Einaudi MA, Hassid S, Chau C, Shojai R, Thomachot L, D'Ercole C, Gire C
Fetal Diagn Ther 2004 Jul-Aug;19(4):373-6. doi: 10.1159/000077969. PMID: 15192300

Recent clinical studies

Etiology

Proposal for the surgical management of children with laryngeal saccular Cysts: A case series.
Rosas A, McCrary HC, Meier JD, Muntz HR, Park AH
Int J Pediatr Otorhinolaryngol 2019 Nov;126:109604. Epub 2019 Jul 26 doi: 10.1016/j.ijporl.2019.109604. PMID: 31369973
Difficulties in diagnosis of laryngeal cysts in children.
Zawadzka-Glos L, Frackiewicz M, Brzewski M, Biejat A, Chmielik M
Int J Pediatr Otorhinolaryngol 2009 Dec;73(12):1729-31. Epub 2009 Oct 2 doi: 10.1016/j.ijporl.2009.09.010. PMID: 19800698
Series of congenital vallecular cysts: a rare yet potentially fatal cause of upper airway obstruction and failure to thrive in the newborn.
Sands NB, Anand SM, Manoukian JJ
J Otolaryngol Head Neck Surg 2009 Feb;38(1):6-10. PMID: 19344606
Urgent awake tracheotomy for impending airway obstruction.
Yuen HW, Loy AH, Johari S
Otolaryngol Head Neck Surg 2007 May;136(5):838-42. doi: 10.1016/j.otohns.2006.12.012. PMID: 17478226
Congenital high airway obstruction syndrome: natural history and management.
Lim FY, Crombleholme TM, Hedrick HL, Flake AW, Johnson MP, Howell LJ, Adzick NS
J Pediatr Surg 2003 Jun;38(6):940-5. doi: 10.1016/s0022-3468(03)00128-3. PMID: 12778398

Diagnosis

Rare cause of voice muffling: pyogenic vallecular cyst.
Ting LKN, Idris A, Mat Baki M
BMJ Case Rep 2022 Sep 15;15(9) doi: 10.1136/bcr-2022-250615. PMID: 36109094Free PMC Article
Thyroglossal Duct Cyst Occupying Posterior Hyoid Space with Endolaryngeal Extension Presenting After Neck Trauma.
Bosco S, Cohn JE, Evarts M, Papajohn P, Lesser R
Ann Otol Rhinol Laryngol 2020 Jun;129(6):628-632. Epub 2020 Jan 22 doi: 10.1177/0003489419901140. PMID: 31965811
Transoral robotic excision of laryngocele: Surgical considerations.
Patel KB, Lin C, Kramer S, Fada C, Ozer E
Head Neck 2019 Apr;41(4):1140-1143. Epub 2019 Jan 16 doi: 10.1002/hed.25612. PMID: 30652374
Laryngeal Cysts in Adults: Simplifying Classification and Management.
Heyes R, Lott DG
Otolaryngol Head Neck Surg 2017 Dec;157(6):928-939. Epub 2017 Jul 11 doi: 10.1177/0194599817715613. PMID: 28695764
Neonatal stridor and laryngeal cyst: Which comes first?
Marseglia L, D'Angelo G, Impellizzeri P, Salvo V, Catalano N, Bruno R, Galletti C, Galletti B, Galletti F, Gitto E
Pediatr Int 2017 Jan;59(1):115-117. doi: 10.1111/ped.13192. PMID: 28102625

Therapy

Rare cause of voice muffling: pyogenic vallecular cyst.
Ting LKN, Idris A, Mat Baki M
BMJ Case Rep 2022 Sep 15;15(9) doi: 10.1136/bcr-2022-250615. PMID: 36109094Free PMC Article
Autofluorescence spectroscopy in the differentiation of laryngeal epithelial lesions - preliminary results.
Winiarski P, Szewczyk-Golec K, Orłowski P, Kałużna E, Wamka M, Mackiewicz-Nartowicz H, Sinkiewicz A, Fisz JJ
Acta Otolaryngol 2016 Jun;136(6):580-4. Epub 2016 Feb 16 doi: 10.3109/00016489.2016.1142116. PMID: 26881757
Excision of laryngocele via transcervical midline approach.
Vengerovich G, McCoul ED, Burstein DH, Yao FB, Lim JW
Laryngoscope 2010;120 Suppl 4:S189. doi: 10.1002/lary.21653. PMID: 21225787
Large B-cell non-Hodgkin's lymphoma presenting as a laryngeal cyst.
Agada FO, Mistry D, Grace AR, Coatesworth AP
J Laryngol Otol 2005 Aug;119(8):658-60. doi: 10.1258/0022215054516287. PMID: 16102228
Pseudopolyp of the right laryngeal ventricle following atraumatic intubation: a diagnostic dilemma.
Smith OD, Callanan V, Lloyd-Thomas A, Albert DM
Paediatr Anaesth 2000;10(5):559-62. doi: 10.1046/j.1460-9592.2000.00553.x. PMID: 11012963

Prognosis

Rare cause of voice muffling: pyogenic vallecular cyst.
Ting LKN, Idris A, Mat Baki M
BMJ Case Rep 2022 Sep 15;15(9) doi: 10.1136/bcr-2022-250615. PMID: 36109094Free PMC Article
Congenital high airway obstruction syndrome.
Hamid-Sowinska A, Ropacka-Lesiak M, Breborowicz GH
Neuro Endocrinol Lett 2011;32(5):623-6. PMID: 22167132
Difficulties in diagnosis of laryngeal cysts in children.
Zawadzka-Glos L, Frackiewicz M, Brzewski M, Biejat A, Chmielik M
Int J Pediatr Otorhinolaryngol 2009 Dec;73(12):1729-31. Epub 2009 Oct 2 doi: 10.1016/j.ijporl.2009.09.010. PMID: 19800698
Congenital high airway obstruction syndrome: natural history and management.
Lim FY, Crombleholme TM, Hedrick HL, Flake AW, Johnson MP, Howell LJ, Adzick NS
J Pediatr Surg 2003 Jun;38(6):940-5. doi: 10.1016/s0022-3468(03)00128-3. PMID: 12778398
Congenital laryngeal cyst in infancy. A rare cause of life-threatening stridor.
Kristensen S, Tveterås K
ORL J Otorhinolaryngol Relat Spec 1986;48(3):150-5. doi: 10.1159/000275860. PMID: 3714197

Clinical prediction guides

Misguidance of peroral rigid laryngoscopy in assessment of difficult airway: two comparable cases in microlaryngeal surgery.
Zhang X, Li W
BMJ Case Rep 2013 May 22;2013 doi: 10.1136/bcr-2012-008423. PMID: 23704425Free PMC Article
Pseudopolyp of the right laryngeal ventricle following atraumatic intubation: a diagnostic dilemma.
Smith OD, Callanan V, Lloyd-Thomas A, Albert DM
Paediatr Anaesth 2000;10(5):559-62. doi: 10.1046/j.1460-9592.2000.00553.x. PMID: 11012963

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