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Visceral pain

MedGen UID:
452294
•Concept ID:
C0234245
•
Sign or Symptom
Synonyms: Pain, Visceral; Pains, Visceral; Visceral Pain; Visceral Pains
SNOMED CT: Visceral pain (73645008); Autonomic pain (73645008)

Definition

Pain originating from internal organs (VISCERA) associated with autonomic phenomena (PALLOR; SWEATING; NAUSEA; and VOMITING). It often becomes a REFERRED PAIN. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVisceral pain

Professional guidelines

PubMed

Lidocaine Infusions for Pain Management in Pediatrics.
Hall EA, Sauer HE, Davis MS, Anghelescu DL
Paediatr Drugs 2021 Jul;23(4):349-359. Epub 2021 May 26 doi: 10.1007/s40272-021-00454-2. PMID: 34036532Free PMC Article
Abdominal Wall Pain: Clinical Evaluation, Differential Diagnosis, and Treatment.
Shian B, Larson ST
Am Fam Physician 2018 Oct 1;98(7):429-436. PMID: 30252418
Central sensitization: implications for the diagnosis and treatment of pain.
Woolf CJ
Pain 2011 Mar;152(3 Suppl):S2-S15. Epub 2010 Oct 18 doi: 10.1016/j.pain.2010.09.030. PMID: 20961685Free PMC Article

Recent clinical studies

Etiology

Macrophage as a Peripheral Pain Regulator.
Domoto R, Sekiguchi F, Tsubota M, Kawabata A
Cells 2021 Jul 24;10(8) doi: 10.3390/cells10081881. PMID: 34440650Free PMC Article
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11).
Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ
Pain 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384. PMID: 30586067
Visceral Pain and Psychiatric Disorders.
Felice VD, Moloney RD, Cryan JF, Dinan TG, O'Mahony SM
Mod Trends Pharmacopsychiatry 2015;30:103-19. Epub 2015 Sep 18 doi: 10.1159/000435936. PMID: 26436661
Chronic pancreatitis.
DiMagno MJ, DiMagno EP
Curr Opin Gastroenterol 2013 Sep;29(5):531-6. doi: 10.1097/MOG.0b013e3283639370. PMID: 23852141Free PMC Article
Central sensitization: implications for the diagnosis and treatment of pain.
Woolf CJ
Pain 2011 Mar;152(3 Suppl):S2-S15. Epub 2010 Oct 18 doi: 10.1016/j.pain.2010.09.030. PMID: 20961685Free PMC Article

Diagnosis

MODERN APPROACH TO DYSPEPSIA.
Medić B, Babić Ž, Banić M, Ljubičić L
Acta Clin Croat 2021 Dec;60(4):731-738. doi: 10.20471/acc.2021.60.04.21. PMID: 35734496Free PMC Article
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11).
Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Korwisi B, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ
Pain 2019 Jan;160(1):19-27. doi: 10.1097/j.pain.0000000000001384. PMID: 30586067
Abdominal Wall Pain: Clinical Evaluation, Differential Diagnosis, and Treatment.
Shian B, Larson ST
Am Fam Physician 2018 Oct 1;98(7):429-436. PMID: 30252418
Gastrointestinal Physiology and Function.
Greenwood-Van Meerveld B, Johnson AC, Grundy D
Handb Exp Pharmacol 2017;239:1-16. doi: 10.1007/164_2016_118. PMID: 28176047
Central sensitization: implications for the diagnosis and treatment of pain.
Woolf CJ
Pain 2011 Mar;152(3 Suppl):S2-S15. Epub 2010 Oct 18 doi: 10.1016/j.pain.2010.09.030. PMID: 20961685Free PMC Article

Therapy

MODERN APPROACH TO DYSPEPSIA.
Medić B, Babić Ž, Banić M, Ljubičić L
Acta Clin Croat 2021 Dec;60(4):731-738. doi: 10.20471/acc.2021.60.04.21. PMID: 35734496Free PMC Article
Lidocaine Infusions for Pain Management in Pediatrics.
Hall EA, Sauer HE, Davis MS, Anghelescu DL
Paediatr Drugs 2021 Jul;23(4):349-359. Epub 2021 May 26 doi: 10.1007/s40272-021-00454-2. PMID: 34036532Free PMC Article
Management Options for Irritable Bowel Syndrome.
Camilleri M
Mayo Clin Proc 2018 Dec;93(12):1858-1872. doi: 10.1016/j.mayocp.2018.04.032. PMID: 30522596Free PMC Article
Capsaicin, Nociception and Pain.
Frias B, Merighi A
Molecules 2016 Jun 18;21(6) doi: 10.3390/molecules21060797. PMID: 27322240Free PMC Article
Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome.
Moloney RD, Johnson AC, O'Mahony SM, Dinan TG, Greenwood-Van Meerveld B, Cryan JF
CNS Neurosci Ther 2016 Feb;22(2):102-17. Epub 2015 Dec 10 doi: 10.1111/cns.12490. PMID: 26662472Free PMC Article

Prognosis

Pain modalities in the body and brain: Current knowledge and future perspectives.
Chae Y, Park HJ, Lee IS
Neurosci Biobehav Rev 2022 Aug;139:104744. Epub 2022 Jun 15 doi: 10.1016/j.neubiorev.2022.104744. PMID: 35716877
Preclinical Assessment of Inflammatory Pain.
Muley MM, Krustev E, McDougall JJ
CNS Neurosci Ther 2016 Feb;22(2):88-101. Epub 2015 Dec 10 doi: 10.1111/cns.12486. PMID: 26663896Free PMC Article
Neuroplasticity and dysfunction after gastrointestinal inflammation.
Brierley SM, Linden DR
Nat Rev Gastroenterol Hepatol 2014 Oct;11(10):611-27. Epub 2014 Jul 8 doi: 10.1038/nrgastro.2014.103. PMID: 25001973
Chronic pancreatitis.
DiMagno MJ, DiMagno EP
Curr Opin Gastroenterol 2013 Sep;29(5):531-6. doi: 10.1097/MOG.0b013e3283639370. PMID: 23852141Free PMC Article
Imaging visceral pain.
Derbyshire SW
Curr Pain Headache Rep 2007 Jun;11(3):178-82. doi: 10.1007/s11916-007-0188-2. PMID: 17504644

Clinical prediction guides

Interactions between the painful disorders and the autonomic nervous system.
Arslan D, Ünal Çevik I
Agri 2022 Jul;34(3):155-165. doi: 10.14744/agri.2021.43078. PMID: 35792695
Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity.
Zhu Y, Xu F, Lu D, Rong P, Cheng J, Li M, Gong Y, Sun C, Wei W, Lin L, Chen JDZ
Am J Physiol Gastrointest Liver Physiol 2021 May 1;320(5):G700-G711. Epub 2021 Feb 24 doi: 10.1152/ajpgi.00426.2020. PMID: 33624527Free PMC Article
Co-occurrence of pain syndromes.
Affaitati G, Costantini R, Tana C, Cipollone F, Giamberardino MA
J Neural Transm (Vienna) 2020 Apr;127(4):625-646. Epub 2019 Nov 29 doi: 10.1007/s00702-019-02107-8. PMID: 31784821
Preclinical Assessment of Inflammatory Pain.
Muley MM, Krustev E, McDougall JJ
CNS Neurosci Ther 2016 Feb;22(2):88-101. Epub 2015 Dec 10 doi: 10.1111/cns.12486. PMID: 26663896Free PMC Article
Chronic pancreatitis.
DiMagno MJ, DiMagno EP
Curr Opin Gastroenterol 2013 Sep;29(5):531-6. doi: 10.1097/MOG.0b013e3283639370. PMID: 23852141Free PMC Article

Recent systematic reviews

Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review.
Halloum W, Dughem YA, Beier D, Pellesi L
J Headache Pain 2024 Jul 12;25(1):112. doi: 10.1186/s10194-024-01821-3. PMID: 38997662Free PMC Article
Prevalence of chronic pain after spinal cord injury: a systematic review and meta-analysis.
Hunt C, Moman R, Peterson A, Wilson R, Covington S, Mustafa R, Murad MH, Hooten WM
Reg Anesth Pain Med 2021 Apr;46(4):328-336. Epub 2021 Jan 6 doi: 10.1136/rapm-2020-101960. PMID: 33408161
Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations.
Mercadante S, Klepstad P, Kurita GP, Sjøgren P, Giarratano A; European Palliative Care Research Collaborative (EPCRC)
Crit Rev Oncol Hematol 2015 Dec;96(3):577-83. Epub 2015 Aug 1 doi: 10.1016/j.critrevonc.2015.07.014. PMID: 26297518
Systematic review: instruments to assess abdominal pain in irritable bowel syndrome.
Mujagic Z, Keszthelyi D, Aziz Q, Reinisch W, Quetglas EG, De Leonardis F, Segerdahl M, Masclee AA
Aliment Pharmacol Ther 2015 Nov;42(9):1064-81. Epub 2015 Aug 20 doi: 10.1111/apt.13378. PMID: 26290286
Early pain after laparoscopic inguinal hernia repair. A qualitative systematic review.
Tolver MA, Rosenberg J, Bisgaard T
Acta Anaesthesiol Scand 2012 May;56(5):549-57. Epub 2012 Jan 19 doi: 10.1111/j.1399-6576.2011.02633.x. PMID: 22260427

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