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Blood transfusion reaction

MedGen UID:
452371
•Concept ID:
C0274435
•
Pathologic Function
Synonyms: Blood Transfusion Associated Adverse Reactions; Blood Transfusion-Associated Adverse Reactions; Transfusion Reaction; Transfusion Reactions
SNOMED CT: Blood transfusion reaction (82545002); Complication of blood transfusion (82545002); Transfusion reaction (82545002)

Definition

Adverse events associated with the transfusion of whole blood or one of its components, most commonly a hemolytic reaction to cross-typed blood. [from NCI]

Professional guidelines

PubMed

Management of mismatched blood transfusion reaction.
Gopalrao T
J Med Soc N J 1973 Mar;70(3):181-4. PMID: 4510801

Recent clinical studies

Etiology

CE: Recognizing Transfusion-Associated Circulatory Overload.
Smith CM
Am J Nurs 2023 Nov 1;123(11):34-41. doi: 10.1097/01.NAJ.0000995356.33506.f5. PMID: 37882401
Is This a Blood Transfusion Reaction? Don't Hesitate; Check It Out.
DeLisle J
J Infus Nurs 2018 Jan/Feb;41(1):43-51. doi: 10.1097/NAN.0000000000000261. PMID: 29293197
Autologous Blood Transfusion for Postpartum Hemorrhage.
Greenawalt JA, Zernell D
MCN Am J Matern Child Nurs 2017 Sep/Oct;42(5):269-275. doi: 10.1097/NMC.0000000000000359. PMID: 28816806
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2016 Dec 22;12(12):CD010378. doi: 10.1002/14651858.CD010378.pub3. PMID: 28005272Free PMC Article
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2013 Dec 3;(12):CD010378. doi: 10.1002/14651858.CD010378.pub2. PMID: 24297507

Diagnosis

Intraoperative Diagnosis and Management of Acute Hypotensive Blood Transfusion Reaction (AHTR): A Report of Two Cases.
Yoon U, Abdullah M, Elia E, Herman J
Am J Case Rep 2018 Oct 29;19:1283-1287. doi: 10.12659/AJCR.910642. PMID: 30369594Free PMC Article
Acute respiratory failure during routine blood transfusion: a case report and review of the literature.
Torbati SS, Schlesinger S, Niku D
J Emerg Med 2014 Mar;46(3):341-4. Epub 2013 Dec 17 doi: 10.1016/j.jemermed.2013.08.101. PMID: 24360126
Transient blood transfusion reaction masquerading as a post-transplantation lymphoproliferative disorder mimicking acute leukemia cutis.
Gan Y, Shinohara MM, Rosenbach M, Elder D, Frey N, Bagg A
J Clin Oncol 2011 Oct 10;29(29):e751-3. Epub 2011 Sep 6 doi: 10.1200/JCO.2011.36.5296. PMID: 21900116
Blood transfusions. 2: Signs and symptoms of acute reactions.
Thompson CL, Edwards C, Stout L
Nurs Times 2008 Jan 22-28;104(3):28-9. PMID: 18293877
Fatal transfusion reaction due to Serratia marcescens.
Black WA, Pollock A, Batchelor EL
J Clin Pathol 1967 Nov;20(6):883-6. doi: 10.1136/jcp.20.6.883. PMID: 5614073Free PMC Article

Therapy

Fertility preservation in female patients with hematological disorders.
Wu D, Shen H
BMC Pregnancy Childbirth 2022 Jan 22;22(1):61. doi: 10.1186/s12884-022-04385-9. PMID: 35065646Free PMC Article
Intraoperative Diagnosis and Management of Acute Hypotensive Blood Transfusion Reaction (AHTR): A Report of Two Cases.
Yoon U, Abdullah M, Elia E, Herman J
Am J Case Rep 2018 Oct 29;19:1283-1287. doi: 10.12659/AJCR.910642. PMID: 30369594Free PMC Article
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2016 Dec 22;12(12):CD010378. doi: 10.1002/14651858.CD010378.pub3. PMID: 28005272Free PMC Article
Acute respiratory failure during routine blood transfusion: a case report and review of the literature.
Torbati SS, Schlesinger S, Niku D
J Emerg Med 2014 Mar;46(3):341-4. Epub 2013 Dec 17 doi: 10.1016/j.jemermed.2013.08.101. PMID: 24360126
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2013 Dec 3;(12):CD010378. doi: 10.1002/14651858.CD010378.pub2. PMID: 24297507

Prognosis

CE: Recognizing Transfusion-Associated Circulatory Overload.
Smith CM
Am J Nurs 2023 Nov 1;123(11):34-41. doi: 10.1097/01.NAJ.0000995356.33506.f5. PMID: 37882401
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2016 Dec 22;12(12):CD010378. doi: 10.1002/14651858.CD010378.pub3. PMID: 28005272Free PMC Article
Radical hysterectomy with bilateral pelvic node dissection. Our experience at the Philippine General Hospital.
Sotto LS
Eur J Gynaecol Oncol 1990;11(6):447-52. PMID: 2086226

Clinical prediction guides

Fertility preservation in female patients with hematological disorders.
Wu D, Shen H
BMC Pregnancy Childbirth 2022 Jan 22;22(1):61. doi: 10.1186/s12884-022-04385-9. PMID: 35065646Free PMC Article
Failure mode and effect analysis in blood transfusion: a proactive tool to reduce risks.
Lu Y, Teng F, Zhou J, Wen A, Bi Y
Transfusion 2013 Dec;53(12):3080-7. Epub 2013 Apr 8 doi: 10.1111/trf.12174. PMID: 23560475
Blood transfusions. 2: Signs and symptoms of acute reactions.
Thompson CL, Edwards C, Stout L
Nurs Times 2008 Jan 22-28;104(3):28-9. PMID: 18293877

Recent systematic reviews

Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2016 Dec 22;12(12):CD010378. doi: 10.1002/14651858.CD010378.pub3. PMID: 28005272Free PMC Article
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy.
Okusanya BO, Oladapo OT
Cochrane Database Syst Rev 2013 Dec 3;(12):CD010378. doi: 10.1002/14651858.CD010378.pub2. PMID: 24297507

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