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Hematopoietic and Lymphoid System Disorder

MedGen UID:
208860
Concept ID:
C0851353
Disease or Syndrome
Synonyms: Blood and Lymphatic System Disorders; Hemic and Lymphatic Diseases

Definition

Any deviation from the normal structure or function of the blood or lymphatic system that is manifested by a characteristic set of symptoms and signs. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHematopoietic and Lymphoid System Disorder

Professional guidelines

PubMed

Dimopoulos MA, Moreau P, Terpos E, Mateos MV, Zweegman S, Cook G, Delforge M, Hájek R, Schjesvold F, Cavo M, Goldschmidt H, Facon T, Einsele H, Boccadoro M, San-Miguel J, Sonneveld P, Mey U; EHA Guidelines Committee. Electronic address: guidelines@ehaweb.org; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2021 Mar;32(3):309-322. Epub 2021 Feb 3 doi: 10.1016/j.annonc.2020.11.014. PMID: 33549387
McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, Baker AL, Jackson MA, Takahashi M, Shah PB, Kobayashi T, Wu MH, Saji TT, Pahl E; American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Surgery and Anesthesia; and Council on Epidemiology and Prevention
Circulation 2017 Apr 25;135(17):e927-e999. Epub 2017 Mar 29 doi: 10.1161/CIR.0000000000000484. PMID: 28356445
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, DE Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA
J Thromb Haemost 2006 Feb;4(2):295-306. doi: 10.1111/j.1538-7836.2006.01753.x. PMID: 16420554

Recent clinical studies

Etiology

Li H, Hu F, Gale RP, Sekeres MA, Liang Y
Nat Rev Dis Primers 2022 Nov 17;8(1):74. doi: 10.1038/s41572-022-00402-5. PMID: 36396662
Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, Wang SA, Bagg A, Barbui T, Branford S, Bueso-Ramos CE, Cortes JE, Dal Cin P, DiNardo CD, Dombret H, Duncavage EJ, Ebert BL, Estey EH, Facchetti F, Foucar K, Gangat N, Gianelli U, Godley LA, Gökbuget N, Gotlib J, Hellström-Lindberg E, Hobbs GS, Hoffman R, Jabbour EJ, Kiladjian JJ, Larson RA, Le Beau MM, Loh ML, Löwenberg B, Macintyre E, Malcovati L, Mullighan CG, Niemeyer C, Odenike OM, Ogawa S, Orfao A, Papaemmanuil E, Passamonti F, Porkka K, Pui CH, Radich JP, Reiter A, Rozman M, Rudelius M, Savona MR, Schiffer CA, Schmitt-Graeff A, Shimamura A, Sierra J, Stock WA, Stone RM, Tallman MS, Thiele J, Tien HF, Tzankov A, Vannucchi AM, Vyas P, Wei AH, Weinberg OK, Wierzbowska A, Cazzola M, Döhner H, Tefferi A
Blood 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850. PMID: 35767897Free PMC Article
Gallagher PG
Blood 2022 Aug 11;140(6):571-593. doi: 10.1182/blood.2020006479. PMID: 35213686Free PMC Article
Jain AG, Zhang L, Bennett JM, Komrokji R
Ann Lab Med 2022 May 1;42(3):299-305. doi: 10.3343/alm.2022.42.3.299. PMID: 34907099Free PMC Article
Giammarco S, Chiusolo P, Piccirillo N, Di Giovanni A, Metafuni E, Laurenti L, Sica S, Pagano L
Expert Rev Hematol 2017 Feb;10(2):147-154. Epub 2016 Dec 26 doi: 10.1080/17474086.2017.1270754. PMID: 27967252

Diagnosis

Falini B, Martelli MP
Am J Hematol 2023 Mar;98(3):481-492. Epub 2023 Jan 5 doi: 10.1002/ajh.26812. PMID: 36606297
Scheckel CJ, Go RS
Hematol Oncol Clin North Am 2022 Apr;36(2):315-324. Epub 2022 Mar 11 doi: 10.1016/j.hoc.2021.12.001. PMID: 35282951
Michel M
Hematol Oncol Clin North Am 2022 Apr;36(2):381-392. Epub 2022 Mar 11 doi: 10.1016/j.hoc.2021.12.004. PMID: 35282950
McClain KL, Bigenwald C, Collin M, Haroche J, Marsh RA, Merad M, Picarsic J, Ribeiro KB, Allen CE
Nat Rev Dis Primers 2021 Oct 7;7(1):73. doi: 10.1038/s41572-021-00307-9. PMID: 34620874Free PMC Article
Grada AA, Phillips TJ
J Am Acad Dermatol 2017 Dec;77(6):1009-1020. doi: 10.1016/j.jaad.2017.03.022. PMID: 29132848

Therapy

Verstovsek S, Mesa R, Gupta V, Lavie D, Dubruille V, Cambier N, Platzbecker U, Hus M, Xicoy B, Oh ST, Kiladjian JJ, Vannucchi AM, Gerds A, Egyed M, Mayer J, Sacha T, Kawashima J, Morris M, Huang M, Harrison C
Blood Adv 2023 Jul 25;7(14):3582-3591. doi: 10.1182/bloodadvances.2022009311. PMID: 37042865Free PMC Article
Santini V
Curr Opin Oncol 2021 Nov 1;33(6):681-686. doi: 10.1097/CCO.0000000000000790. PMID: 34474438
Ezzo J, Manheimer E, McNeely ML, Howell DM, Weiss R, Johansson KI, Bao T, Bily L, Tuppo CM, Williams AF, Karadibak D
Cochrane Database Syst Rev 2015 May 21;2015(5):CD003475. doi: 10.1002/14651858.CD003475.pub2. PMID: 25994425Free PMC Article
Rajkumar SV, Harousseau JL, Durie B, Anderson KC, Dimopoulos M, Kyle R, Blade J, Richardson P, Orlowski R, Siegel D, Jagannath S, Facon T, Avet-Loiseau H, Lonial S, Palumbo A, Zonder J, Ludwig H, Vesole D, Sezer O, Munshi NC, San Miguel J; International Myeloma Workshop Consensus Panel 1
Blood 2011 May 5;117(18):4691-5. Epub 2011 Feb 3 doi: 10.1182/blood-2010-10-299487. PMID: 21292775Free PMC Article
Cheson BD, Bennett JM, Kopecky KJ, Büchner T, Willman CL, Estey EH, Schiffer CA, Doehner H, Tallman MS, Lister TA, Lo-Coco F, Willemze R, Biondi A, Hiddemann W, Larson RA, Löwenberg B, Sanz MA, Head DR, Ohno R, Bloomfield CD; International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
J Clin Oncol 2003 Dec 15;21(24):4642-9. doi: 10.1200/JCO.2003.04.036. PMID: 14673054

Prognosis

Liu J, Liu W, Mi L, Zeng X, Cai C, Ma J, Wang L; Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology; Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology
J Hematol Oncol 2019 Dec 10;12(1):136. doi: 10.1186/s13045-019-0807-5. PMID: 31823802Free PMC Article
Siegal T, Bairey O
Acta Haematol 2019;141(3):138-145. Epub 2019 Feb 15 doi: 10.1159/000495284. PMID: 30783026
Deschler B, Lübbert M
Cancer 2006 Nov 1;107(9):2099-107. doi: 10.1002/cncr.22233. PMID: 17019734
Hasserjian RP, Ströbel P, Marx A
Semin Thorac Cardiovasc Surg 2005 Spring;17(1):2-11. doi: 10.1053/j.semtcvs.2004.12.002. PMID: 16104355
International Non-Hodgkin's Lymphoma Prognostic Factors Project
N Engl J Med 1993 Sep 30;329(14):987-94. doi: 10.1056/NEJM199309303291402. PMID: 8141877

Clinical prediction guides

Harkins RA, Chang A, Patel SP, Lee MJ, Goldstein JS, Merdan S, Flowers CR, Koff JL
Expert Rev Hematol 2019 Nov;12(11):959-973. Epub 2019 Sep 12 doi: 10.1080/17474086.2019.1660159. PMID: 31513757Free PMC Article
Hsu MC, Itkin M
Tech Vasc Interv Radiol 2016 Dec;19(4):247-254. Epub 2016 Oct 8 doi: 10.1053/j.tvir.2016.10.003. PMID: 27993319
Itkin M
Tech Vasc Interv Radiol 2016 Dec;19(4):245-246. Epub 2016 Oct 7 doi: 10.1053/j.tvir.2016.10.004. PMID: 27993318
James P, Coller BS
Curr Opin Hematol 2012 Sep;19(5):406-12. doi: 10.1097/MOH.0b013e32835673ab. PMID: 22759628Free PMC Article
Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A
J Thromb Haemost 2006 Apr;4(4):759-65. doi: 10.1111/j.1538-7836.2006.01787.x. PMID: 16634744

Recent systematic reviews

Shakoory B, Geerlinks A, Wilejto M, Kernan K, Hines M, Romano M, Piskin D, Ravelli A, Sinha R, Aletaha D, Allen C, Bassiri H, Behrens EM, Carcillo J, Carl L, Chatham W, Cohen JI, Cron RQ, Drewniak E, Grom AA, Henderson LA, Horne A, Jordan MB, Nichols KE, Schulert G, Vastert S, Demirkaya E, Goldbach-Mansky R, de Benedetti F, Marsh RA, Canna SW; HLH/MAS task force
Ann Rheum Dis 2023 Oct;82(10):1271-1285. Epub 2023 Jul 24 doi: 10.1136/ard-2023-224123. PMID: 37487610Free PMC Article
Torgbenu E, Luckett T, Buhagiar MA, Phillips JL
Adv Wound Care (New Rochelle) 2023 Jan;12(1):15-27. Epub 2022 Apr 6 doi: 10.1089/wound.2021.0149. PMID: 35196892
Cotter J, Baldaia C, Ferreira M, Macedo G, Pedroto I
World J Gastroenterol 2020 Dec 7;26(45):7242-7257. doi: 10.3748/wjg.v26.i45.7242. PMID: 33362380Free PMC Article
Hayden A, Park S, Giustini D, Lee AY, Chen LY
Blood Rev 2016 Nov;30(6):411-420. Epub 2016 May 20 doi: 10.1016/j.blre.2016.05.001. PMID: 27238576
Singh B, Disipio T, Peake J, Hayes SC
Arch Phys Med Rehabil 2016 Feb;97(2):302-315.e13. Epub 2015 Oct 9 doi: 10.1016/j.apmr.2015.09.012. PMID: 26440777

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