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Psychotic Disorder Due to a General Medical Condition

MedGen UID:
452720
•Concept ID:
C0748076
•
Mental or Behavioral Dysfunction

Definition

A psychotic disorder characterized by prominent hallucinations or delusions that have been determined to be etiologically linked to a general medical condition. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPsychotic Disorder Due to a General Medical Condition

Professional guidelines

PubMed

Pre-treatment, baseline, and outcome differences between early-onset and adult-onset psychosis in an epidemiological cohort of 636 first-episode patients.
Schimmelmann BG, Conus P, Cotton S, McGorry PD, Lambert M
Schizophr Res 2007 Sep;95(1-3):1-8. Epub 2007 Jul 12 doi: 10.1016/j.schres.2007.06.004. PMID: 17628441
Diagnostic stability 18 months after treatment initiation for first-episode psychosis.
Schimmelmann BG, Conus P, Edwards J, McGorry PD, Lambert M
J Clin Psychiatry 2005 Oct;66(10):1239-46. doi: 10.4088/jcp.v66n1006. PMID: 16259537

Recent clinical studies

Etiology

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature.
Tandon R, Nasrallah H, Akbarian S, Carpenter WT Jr, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, Yassin W, Keshavan M
Schizophr Res 2024 Feb;264:1-28. Epub 2023 Dec 12 doi: 10.1016/j.schres.2023.11.015. PMID: 38086109
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.
Solmi M, Radua J, Olivola M, Croce E, Soardo L, Salazar de Pablo G, Il Shin J, Kirkbride JB, Jones P, Kim JH, Kim JY, Carvalho AF, Seeman MV, Correll CU, Fusar-Poli P
Mol Psychiatry 2022 Jan;27(1):281-295. Epub 2021 Jun 2 doi: 10.1038/s41380-021-01161-7. PMID: 34079068Free PMC Article
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Diagnosis

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.
Solmi M, Radua J, Olivola M, Croce E, Soardo L, Salazar de Pablo G, Il Shin J, Kirkbride JB, Jones P, Kim JH, Kim JY, Carvalho AF, Seeman MV, Correll CU, Fusar-Poli P
Mol Psychiatry 2022 Jan;27(1):281-295. Epub 2021 Jun 2 doi: 10.1038/s41380-021-01161-7. PMID: 34079068Free PMC Article
Psychosis.
Julayanont P, Suryadevara U
Continuum (Minneap Minn) 2021 Dec 1;27(6):1682-1711. doi: 10.1212/CON.0000000000001013. PMID: 34881732
Psychosis.
Schrimpf LA, Aggarwal A, Lauriello J
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):845-860. doi: 10.1212/CON.0000000000000602. PMID: 29851881
Catatonia.
Walther S, Strik W
CNS Spectr 2016 Aug;21(4):341-8. Epub 2016 Jun 3 doi: 10.1017/S1092852916000274. PMID: 27255726

Therapy

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Psychosis.
Julayanont P, Suryadevara U
Continuum (Minneap Minn) 2021 Dec 1;27(6):1682-1711. doi: 10.1212/CON.0000000000001013. PMID: 34881732
Catatonia.
Walther S, Strik W
CNS Spectr 2016 Aug;21(4):341-8. Epub 2016 Jun 3 doi: 10.1017/S1092852916000274. PMID: 27255726
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Prognosis

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature.
Tandon R, Nasrallah H, Akbarian S, Carpenter WT Jr, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, Yassin W, Keshavan M
Schizophr Res 2024 Feb;264:1-28. Epub 2023 Dec 12 doi: 10.1016/j.schres.2023.11.015. PMID: 38086109
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C
JAMA Psychiatry 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. PMID: 32159746
Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features: Neuroimaging Findings in the Context of a Randomized Placebo-Controlled Clinical Trial.
Voineskos AN, Mulsant BH, Dickie EW, Neufeld NH, Rothschild AJ, Whyte EM, Meyers BS, Alexopoulos GS, Hoptman MJ, Lerch JP, Flint AJ
JAMA Psychiatry 2020 Jul 1;77(7):674-683. doi: 10.1001/jamapsychiatry.2020.0036. PMID: 32101271Free PMC Article
Introduction.
Fang Y, Mao R
Adv Exp Med Biol 2019;1180:1-17. doi: 10.1007/978-981-32-9271-0_1. PMID: 31784955
Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period.
Jones I, Chandra PS, Dazzan P, Howard LM
Lancet 2014 Nov 15;384(9956):1789-99. Epub 2014 Nov 14 doi: 10.1016/S0140-6736(14)61278-2. PMID: 25455249

Clinical prediction guides

A mixed-methods review and meta-synthesis of fears of recurrence and progression in people with mental health conditions.
Coutts-Bain D, Sharpe L, Techakesari P, Forrester MA, Hunt C
Clin Psychol Rev 2023 Nov;105:102342. Epub 2023 Sep 23 doi: 10.1016/j.cpr.2023.102342. PMID: 37804564
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E
BMJ 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. PMID: 37648266Free PMC Article
Physicians' and medical students' beliefs and attitudes toward psychotic disorders: A systematic review.
Le Glaz A, Lemey C, Berrouiguet S, Walter M, Lemogne C, Flahault C
J Psychosom Res 2022 Dec;163:111054. Epub 2022 Oct 13 doi: 10.1016/j.jpsychores.2022.111054. PMID: 36272378
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Using antipsychotic agents in older patients.
Alexopoulos GS, Streim J, Carpenter D, Docherty JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients
J Clin Psychiatry 2004;65 Suppl 2:5-99; discussion 100-102; quiz 103-4. PMID: 14994733

Recent systematic reviews

BrainAGE, brain health, and mental disorders: A systematic review.
Seitz-Holland J, Haas SS, Penzel N, Reichenberg A, Pasternak O
Neurosci Biobehav Rev 2024 Apr;159:105581. Epub 2024 Feb 13 doi: 10.1016/j.neubiorev.2024.105581. PMID: 38354871Free PMC Article
Clinical characteristics indexing genetic differences in bipolar disorder - a systematic review.
van Loo HM, de Vries YA, Taylor J, Todorovic L, Dollinger C, Kendler KS
Mol Psychiatry 2023 Sep;28(9):3661-3670. Epub 2023 Nov 15 doi: 10.1038/s41380-023-02297-4. PMID: 37968345
Physicians' and medical students' beliefs and attitudes toward psychotic disorders: A systematic review.
Le Glaz A, Lemey C, Berrouiguet S, Walter M, Lemogne C, Flahault C
J Psychosom Res 2022 Dec;163:111054. Epub 2022 Oct 13 doi: 10.1016/j.jpsychores.2022.111054. PMID: 36272378
Cognitive behavioural therapy (group) for schizophrenia.
Guaiana G, Abbatecola M, Aali G, Tarantino F, Ebuenyi ID, Lucarini V, Li W, Zhang C, Pinto A
Cochrane Database Syst Rev 2022 Jul 12;7(7):CD009608. doi: 10.1002/14651858.CD009608.pub2. PMID: 35866377Free PMC Article
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P, Salazar de Pablo G, Correll CU, Meyer-Lindenberg A, Millan MJ, Borgwardt S, Galderisi S, Bechdolf A, Pfennig A, Kessing LV, van Amelsvoort T, Nieman DH, Domschke K, Krebs MO, Koutsouleris N, McGuire P, Do KQ, Arango C
JAMA Psychiatry 2020 Jul 1;77(7):755-765. doi: 10.1001/jamapsychiatry.2019.4779. PMID: 32159746

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