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Delirium Due to a General Medical Condition

MedGen UID:
452767
Concept ID:
C0860621
Mental or Behavioral Dysfunction

Definition

A disorder characterized by the acute and sudden development of changes in attention, memory, language and/or perception that can be etiologically linked to the direct physiological consequences of a general medical condition. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelirium Due to a General Medical Condition

Professional guidelines

PubMed

Rosen JH, Bieber E, Matta SE, Sayde GE, Fedotova NO, deVries J, Rafferty M, Stern TA
Prim Care Companion CNS Disord 2024 Feb 8;26(1) doi: 10.4088/PCC.23f03602. PMID: 38334398
Latronico N, Rasulo FA, Eikermann M, Piva S
Crit Care 2023 Nov 13;27(1):439. doi: 10.1186/s13054-023-04676-3. PMID: 37957759Free PMC Article
Sherer M, Katz DI, Bodien YG, Arciniegas DB, Block C, Blum S, Doiron M, Frey K, Giacino JT, Graf MJP, Greenwald B, Hammond FM, Kalmar K, Kean J, Kraus MF, Nakase-Richardson R, Pavawalla S, Rosenbaum A, Stuss DT, Yablon SA
Arch Phys Med Rehabil 2020 Nov;101(11):2041-2050. Epub 2020 Jul 29 doi: 10.1016/j.apmr.2020.06.021. PMID: 32738198

Recent clinical studies

Etiology

Latronico N, Rasulo FA, Eikermann M, Piva S
Crit Care 2023 Nov 13;27(1):439. doi: 10.1186/s13054-023-04676-3. PMID: 37957759Free PMC Article
Fong TG, Inouye SK
Nat Rev Neurol 2022 Oct;18(10):579-596. Epub 2022 Aug 26 doi: 10.1038/s41582-022-00698-7. PMID: 36028563Free PMC Article
Tonna JE, Dalton A, Presson AP, Zhang C, Colantuoni E, Lander K, Howard S, Beynon J, Kamdar BB
Chest 2021 Sep;160(3):899-908. Epub 2021 Mar 24 doi: 10.1016/j.chest.2021.03.030. PMID: 33773988Free PMC Article
Shenvi C, Kennedy M, Austin CA, Wilson MP, Gerardi M, Schneider S
Ann Emerg Med 2020 Feb;75(2):136-145. Epub 2019 Sep 26 doi: 10.1016/j.annemergmed.2019.07.023. PMID: 31563402Free PMC Article
Marcantonio ER
N Engl J Med 2017 Oct 12;377(15):1456-1466. doi: 10.1056/NEJMcp1605501. PMID: 29020579Free PMC Article

Diagnosis

Latronico N, Rasulo FA, Eikermann M, Piva S
Crit Care 2023 Nov 13;27(1):439. doi: 10.1186/s13054-023-04676-3. PMID: 37957759Free PMC Article
Connell J, Oldham M, Pandharipande P, Dittus RS, Wilson A, Mart M, Heckers S, Ely EW, Wilson JE
J Intensive Care Med 2023 Feb;38(2):137-150. Epub 2022 Jul 21 doi: 10.1177/08850666221114303. PMID: 35861966
Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, Slooter AJC, Ely EW
Nat Rev Dis Primers 2020 Nov 12;6(1):90. doi: 10.1038/s41572-020-00223-4. PMID: 33184265Free PMC Article
Chanques G, Constantin JM, Devlin JW, Ely EW, Fraser GL, Gélinas C, Girard TD, Guérin C, Jabaudon M, Jaber S, Mehta S, Langer T, Murray MJ, Pandharipande P, Patel B, Payen JF, Puntillo K, Rochwerg B, Shehabi Y, Strøm T, Olsen HT, Kress JP
Intensive Care Med 2020 Dec;46(12):2342-2356. Epub 2020 Nov 10 doi: 10.1007/s00134-020-06307-9. PMID: 33170331Free PMC Article
Schrimpf LA, Aggarwal A, Lauriello J
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):845-860. doi: 10.1212/CON.0000000000000602. PMID: 29851881

Therapy

Tonna JE, Dalton A, Presson AP, Zhang C, Colantuoni E, Lander K, Howard S, Beynon J, Kamdar BB
Chest 2021 Sep;160(3):899-908. Epub 2021 Mar 24 doi: 10.1016/j.chest.2021.03.030. PMID: 33773988Free PMC Article
Chanques G, Constantin JM, Devlin JW, Ely EW, Fraser GL, Gélinas C, Girard TD, Guérin C, Jabaudon M, Jaber S, Mehta S, Langer T, Murray MJ, Pandharipande P, Patel B, Payen JF, Puntillo K, Rochwerg B, Shehabi Y, Strøm T, Olsen HT, Kress JP
Intensive Care Med 2020 Dec;46(12):2342-2356. Epub 2020 Nov 10 doi: 10.1007/s00134-020-06307-9. PMID: 33170331Free PMC Article
Urits I, Peck J, Giacomazzi S, Patel R, Wolf J, Mathew D, Schwartz R, Kassem H, Urman RD, Kaye AD, Viswanath O
Adv Ther 2020 May;37(5):1897-1909. Epub 2020 Apr 9 doi: 10.1007/s12325-020-01317-x. PMID: 32274749
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Coriale G, Vitali M, Cereatti F, Fiore M, Ceccanti M; Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip
Riv Psichiatr 2018 May-Jun;53(3):118-122. doi: 10.1708/2925.29413. PMID: 29912213

Prognosis

Fong TG, Inouye SK
Nat Rev Neurol 2022 Oct;18(10):579-596. Epub 2022 Aug 26 doi: 10.1038/s41582-022-00698-7. PMID: 36028563Free PMC Article
Urits I, Peck J, Giacomazzi S, Patel R, Wolf J, Mathew D, Schwartz R, Kassem H, Urman RD, Kaye AD, Viswanath O
Adv Ther 2020 May;37(5):1897-1909. Epub 2020 Apr 9 doi: 10.1007/s12325-020-01317-x. PMID: 32274749
Magnuson A, Sattar S, Nightingale G, Saracino R, Skonecki E, Trevino KM
Am Soc Clin Oncol Educ Book 2019 Jan;39:e96-e109. Epub 2019 May 17 doi: 10.1200/EDBK_237641. PMID: 31099668
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
Marcantonio ER
N Engl J Med 2017 Oct 12;377(15):1456-1466. doi: 10.1056/NEJMcp1605501. PMID: 29020579Free PMC Article

Clinical prediction guides

Eijlers R, Dierckx B, Staals LM, Berghmans JM, van der Schroeff MP, Strabbing EM, Wijnen RMH, Hillegers MHJ, Legerstee JS, Utens EMWJ
Eur J Anaesthesiol 2019 Oct;36(10):728-737. doi: 10.1097/EJA.0000000000001059. PMID: 31356373Free PMC Article
Magnuson A, Sattar S, Nightingale G, Saracino R, Skonecki E, Trevino KM
Am Soc Clin Oncol Educ Book 2019 Jan;39:e96-e109. Epub 2019 May 17 doi: 10.1200/EDBK_237641. PMID: 31099668
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF
Cochrane Database Syst Rev 2018 Aug 21;8(8):CD012317. doi: 10.1002/14651858.CD012317.pub2. PMID: 30129968Free PMC Article
Norris D, Clark MS, Shipley S
Am Fam Physician 2016 Oct 15;94(8):635-641. PMID: 27929229
Weingart SD, Trueger NS, Wong N, Scofi J, Singh N, Rudolph SS
Ann Emerg Med 2015 Apr;65(4):349-55. Epub 2014 Oct 23 doi: 10.1016/j.annemergmed.2014.09.025. PMID: 25447559

Recent systematic reviews

Hou L, Zhang Q, Cao L, Chen M, Wang Q, Li Y, Li S, Ge L, Yang K
Asian J Psychiatr 2023 Feb;80:103374. Epub 2022 Dec 5 doi: 10.1016/j.ajp.2022.103374. PMID: 36584541
Kim S, Choi E, Jung Y, Jang I
J Clin Nurs 2023 May;32(9-10):1691-1704. Epub 2021 Dec 8 doi: 10.1111/jocn.16157. PMID: 34881476
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF
Cochrane Database Syst Rev 2018 Aug 21;8(8):CD012317. doi: 10.1002/14651858.CD012317.pub2. PMID: 30129968Free PMC Article
Jackson TA, Wilson D, Richardson S, Lord JM
Int J Geriatr Psychiatry 2016 Apr;31(4):392-9. Epub 2015 Aug 24 doi: 10.1002/gps.4344. PMID: 26302258
García PS, Duggan EW, McCullough IL, Lee SC, Fishman D
Clin Ther 2015 Dec 1;37(12):2651-65. Epub 2015 Nov 17 doi: 10.1016/j.clinthera.2015.10.018. PMID: 26598176

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