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Recurrent E. coli infections

MedGen UID:
4543
Concept ID:
C0014836
Disease or Syndrome
Synonyms: E coli Infection; E coli Infections; E. coli Infection; E. coli Infections; Escherichia coli Infection; Escherichia coli Infections; Infection, E coli; Infection, E. coli; Infection, Escherichia coli; Infections, E coli; Infections, Escherichia coli
SNOMED CT: Colibacillosis (71057007); Infection caused by Escherichia coli (71057007); Bacterial infection caused by E. coli (71057007); Escherichia coli infection (71057007); E. coli infection (71057007)
 
HPO: HP:0002740
Monarch Initiative: MONDO:0020920

Definition

Increased susceptibility to infections with Escherichia coli, as manifested by recurrent episodes of infection with this agent. [from HPO]

Conditions with this feature

Granulomatous disease, chronic, X-linked
MedGen UID:
336165
Concept ID:
C1844376
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2
MedGen UID:
383869
Concept ID:
C1856245
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 1
MedGen UID:
341102
Concept ID:
C1856251
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative
MedGen UID:
383872
Concept ID:
C1856255
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.

Professional guidelines

PubMed

Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, Huang Y, Chi M
Int J Mol Sci 2023 Jun 23;24(13) doi: 10.3390/ijms241310537. PMID: 37445714Free PMC Article
Buettcher M, Trueck J, Niederer-Loher A, Heininger U, Agyeman P, Asner S, Berger C, Bielicki J, Kahlert C, Kottanattu L, Meyer Sauteur PM, Paioni P, Posfay-Barbe K, Relly C, Ritz N, Zimmermann P, Zucol F, Gobet R, Shavit S, Rudin C, Laube G, von Vigier R, Neuhaus TJ
Eur J Pediatr 2021 Mar;180(3):663-674. Epub 2020 Jul 3 doi: 10.1007/s00431-020-03714-4. PMID: 32621135Free PMC Article
Kolman KB
Prim Care 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001. PMID: 31030820

Recent clinical studies

Etiology

Iaquinto G, Aufiero VR, Mazzarella G, Lucariello A, Panico L, Melina R, Iaquinto S, De Luca A, Sellitto C
Crit Rev Eukaryot Gene Expr 2024;34(3):83-99. doi: 10.1615/CritRevEukaryotGeneExpr.2023050088. PMID: 38305291
Ala-Jaakkola R, Laitila A, Ouwehand AC, Lehtoranta L
Nutr J 2022 Mar 22;21(1):18. doi: 10.1186/s12937-022-00769-x. PMID: 35313893Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Gomes TA, Elias WP, Scaletsky IC, Guth BE, Rodrigues JF, Piazza RM, Ferreira LC, Martinez MB
Braz J Microbiol 2016 Dec;47 Suppl 1(Suppl 1):3-30. Epub 2016 Nov 5 doi: 10.1016/j.bjm.2016.10.015. PMID: 27866935Free PMC Article
Bryan A, Youngster I, McAdam AJ
Clin Lab Med 2015 Jun;35(2):247-72. Epub 2015 Mar 18 doi: 10.1016/j.cll.2015.02.004. PMID: 26004641

Diagnosis

Fleece ME, Pholwat S, Mathers AJ, Houpt ER
Expert Rev Mol Diagn 2018 Mar;18(3):207-217. Epub 2018 Feb 19 doi: 10.1080/14737159.2018.1439381. PMID: 29431523
Flemmer A
Kinderkrankenschwester 2017 Feb;36(2):64-66. PMID: 30379455
Gomes TA, Elias WP, Scaletsky IC, Guth BE, Rodrigues JF, Piazza RM, Ferreira LC, Martinez MB
Braz J Microbiol 2016 Dec;47 Suppl 1(Suppl 1):3-30. Epub 2016 Nov 5 doi: 10.1016/j.bjm.2016.10.015. PMID: 27866935Free PMC Article
Bryan A, Youngster I, McAdam AJ
Clin Lab Med 2015 Jun;35(2):247-72. Epub 2015 Mar 18 doi: 10.1016/j.cll.2015.02.004. PMID: 26004641
Gaastra W, Kusters JG, van Duijkeren E, Lipman LJ
Vet Microbiol 2014 Aug 6;172(1-2):7-12. Epub 2014 May 9 doi: 10.1016/j.vetmic.2014.04.016. PMID: 24861842

Therapy

Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, Huang Y, Chi M
Int J Mol Sci 2023 Jun 23;24(13) doi: 10.3390/ijms241310537. PMID: 37445714Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Biran D, Ron EZ
Curr Top Microbiol Immunol 2018;416:149-161. doi: 10.1007/82_2018_108. PMID: 30046982
Flemmer A
Kinderkrankenschwester 2017 Feb;36(2):64-66. PMID: 30379455
Gaastra W, Kusters JG, van Duijkeren E, Lipman LJ
Vet Microbiol 2014 Aug 6;172(1-2):7-12. Epub 2014 May 9 doi: 10.1016/j.vetmic.2014.04.016. PMID: 24861842

Prognosis

Tan CW, Chlebicki MP
Singapore Med J 2016 Sep;57(9):485-90. doi: 10.11622/smedj.2016153. PMID: 27662890Free PMC Article
Larsen J, Mühlbauer J, Wigger T, Bardosi A
Lancet Infect Dis 2015 Apr;15(4):486. doi: 10.1016/S1473-3099(14)71017-5. PMID: 25809901
Okamoto H, Kuriyama A
Emerg Med J 2013 May;30(5):396. Epub 2013 Jan 10 doi: 10.1136/emermed-2012-202214. PMID: 23307755
Cavorsi K, Prabhakar P, Kirby C
Ultrasound Q 2010 Jun;26(2):103-5. doi: 10.1097/RUQ.0b013e3181dc7d0b. PMID: 20498566
Parikh TB, Nanavati RN, Udani RH
Indian J Pediatr 2006 May;73(5):439-40. doi: 10.1007/BF02758572. PMID: 16741334

Clinical prediction guides

Bermudez TA, Brannon JR, Dudipala N, Reasoner S, Morales G, Wiebe M, Cecala M, DaCosta M, Beebout C, Amir O, Hadjifrangiskou M
Antimicrob Agents Chemother 2024 Jan 10;68(1):e0080323. Epub 2023 Dec 11 doi: 10.1128/aac.00803-23. PMID: 38078906Free PMC Article
Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, Huang Y, Chi M
Int J Mol Sci 2023 Jun 23;24(13) doi: 10.3390/ijms241310537. PMID: 37445714Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Tandogdu Z, Wagenlehner FM
Curr Opin Infect Dis 2016 Feb;29(1):73-9. doi: 10.1097/QCO.0000000000000228. PMID: 26694621
Obata F
Adv Appl Microbiol 2010;71:1-19. Epub 2010 Feb 20 doi: 10.1016/S0065-2164(10)71001-7. PMID: 20378049

Recent systematic reviews

Williams G, Hahn D, Stephens JH, Craig JC, Hodson EM
Cochrane Database Syst Rev 2023 Apr 17;4(4):CD001321. doi: 10.1002/14651858.CD001321.pub6. PMID: 37068952Free PMC Article
Raoofi S, Pashazadeh Kan F, Rafiei S, Hosseinipalangi Z, Noorani Mejareh Z, Khani S, Abdollahi B, Seyghalani Talab F, Sanaei M, Zarabi F, Dolati Y, Ahmadi N, Raoofi N, Sarhadi Y, Masoumi M, Sadat Hosseini B, Vali N, Gholamali N, Asadi S, Ahmadi S, Ahmadi B, Beiramy Chomalu Z, Asadollahi E, Rajabi M, Gharagozloo D, Nejatifar Z, Soheylirad R, Jalali S, Aghajani F, Navidriahy M, Deylami S, Nasiri M, Zareei M, Golmohammadi Z, Shabani H, Torabi F, Shabaninejad H, Nemati A, Amerzadeh M, Aryankhesal A, Ghashghaee A
PLoS One 2023;18(1):e0274248. Epub 2023 Jan 27 doi: 10.1371/journal.pone.0274248. PMID: 36706112Free PMC Article
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Goodlet KJ, Benhalima FZ, Nailor MD
Antimicrob Agents Chemother 2019 Jan;63(1) Epub 2018 Dec 21 doi: 10.1128/AAC.02165-18. PMID: 30397061Free PMC Article
Kramer A, Schwebke I, Kampf G
BMC Infect Dis 2006 Aug 16;6:130. doi: 10.1186/1471-2334-6-130. PMID: 16914034Free PMC Article

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