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Recurrent E. coli infections

MedGen UID:
4543
Concept ID:
C0014836
Disease or Syndrome
Synonyms: E coli Infection; E coli Infections; E. coli Infection; E. coli Infections; Escherichia coli Infection; Escherichia coli Infections; Infection, E coli; Infection, E. coli; Infection, Escherichia coli; Infections, E coli; Infections, Escherichia coli
SNOMED CT: Colibacillosis (71057007); Infection caused by Escherichia coli (71057007); Bacterial infection caused by E. coli (71057007); Escherichia coli infection (71057007); E. coli infection (71057007)
 
HPO: HP:0002740
Monarch Initiative: MONDO:0020920

Definition

Increased susceptibility to infections with Escherichia coli, as manifested by recurrent episodes of infection with this agent. [from HPO]

Conditions with this feature

Granulomatous disease, chronic, X-linked
MedGen UID:
336165
Concept ID:
C1844376
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2
MedGen UID:
383869
Concept ID:
C1856245
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 1
MedGen UID:
341102
Concept ID:
C1856251
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.
Granulomatous disease, chronic, autosomal recessive, cytochrome b-negative
MedGen UID:
383872
Concept ID:
C1856255
Disease or Syndrome
Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder of phagocytes (neutrophils, monocytes, macrophages, and eosinophils) resulting from impaired killing of bacteria and fungi. CGD is characterized by severe recurrent bacterial and fungal infections and dysregulated inflammatory responses resulting in granuloma formation and other inflammatory disorders such as colitis. Infections typically involve the lung (pneumonia), lymph nodes (lymphadenitis), liver (abscess), bone (osteomyelitis), and skin (abscesses or cellulitis). Granulomas typically involve the genitourinary system (bladder) and gastrointestinal tract (often the pylorus initially, and later the esophagus, jejunum, ileum, cecum, rectum, and perirectal area). Some males with X-linked CGD have McLeod neuroacanthocytosis syndrome as the result of a contiguous gene deletion. While CGD may present anytime from infancy to late adulthood, the vast majority of affected individuals are diagnosed before age five years. Use of antimicrobial prophylaxis and therapy has greatly improved overall survival.

Professional guidelines

PubMed

Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, Huang Y, Chi M
Int J Mol Sci 2023 Jun 23;24(13) doi: 10.3390/ijms241310537. PMID: 37445714Free PMC Article
Buettcher M, Trueck J, Niederer-Loher A, Heininger U, Agyeman P, Asner S, Berger C, Bielicki J, Kahlert C, Kottanattu L, Meyer Sauteur PM, Paioni P, Posfay-Barbe K, Relly C, Ritz N, Zimmermann P, Zucol F, Gobet R, Shavit S, Rudin C, Laube G, von Vigier R, Neuhaus TJ
Eur J Pediatr 2021 Mar;180(3):663-674. Epub 2020 Jul 3 doi: 10.1007/s00431-020-03714-4. PMID: 32621135Free PMC Article
Kolman KB
Prim Care 2019 Jun;46(2):191-202. doi: 10.1016/j.pop.2019.01.001. PMID: 31030820

Recent clinical studies

Etiology

Ala-Jaakkola R, Laitila A, Ouwehand AC, Lehtoranta L
Nutr J 2022 Mar 22;21(1):18. doi: 10.1186/s12937-022-00769-x. PMID: 35313893Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Gomes TA, Elias WP, Scaletsky IC, Guth BE, Rodrigues JF, Piazza RM, Ferreira LC, Martinez MB
Braz J Microbiol 2016 Dec;47 Suppl 1(Suppl 1):3-30. Epub 2016 Nov 5 doi: 10.1016/j.bjm.2016.10.015. PMID: 27866935Free PMC Article
Manges AR
Clin Microbiol Infect 2016 Feb;22(2):122-129. Epub 2015 Dec 8 doi: 10.1016/j.cmi.2015.11.010. PMID: 26679924
Pennington H
Lancet 2010 Oct 23;376(9750):1428-35. doi: 10.1016/S0140-6736(10)60963-4. PMID: 20971366

Diagnosis

Liu Y, Thaker H, Wang C, Xu Z, Dong M
Toxins (Basel) 2022 Dec 23;15(1) doi: 10.3390/toxins15010010. PMID: 36668830Free PMC Article
Gomes TA, Elias WP, Scaletsky IC, Guth BE, Rodrigues JF, Piazza RM, Ferreira LC, Martinez MB
Braz J Microbiol 2016 Dec;47 Suppl 1(Suppl 1):3-30. Epub 2016 Nov 5 doi: 10.1016/j.bjm.2016.10.015. PMID: 27866935Free PMC Article
Kolenda R, Burdukiewicz M, Schierack P
Front Cell Infect Microbiol 2015;5:23. Epub 2015 Mar 12 doi: 10.3389/fcimb.2015.00023. PMID: 25815276Free PMC Article
Gaastra W, Kusters JG, van Duijkeren E, Lipman LJ
Vet Microbiol 2014 Aug 6;172(1-2):7-12. Epub 2014 May 9 doi: 10.1016/j.vetmic.2014.04.016. PMID: 24861842
Tompkins B
Nurs Stand 2011 Mar 23-29;25(29):51-2. doi: 10.7748/ns2011.03.25.29.51.c8403. PMID: 21500690

Therapy

Liu Y, Thaker H, Wang C, Xu Z, Dong M
Toxins (Basel) 2022 Dec 23;15(1) doi: 10.3390/toxins15010010. PMID: 36668830Free PMC Article
Ala-Jaakkola R, Laitila A, Ouwehand AC, Lehtoranta L
Nutr J 2022 Mar 22;21(1):18. doi: 10.1186/s12937-022-00769-x. PMID: 35313893Free PMC Article
Sojo-Dorado J, López-Hernández I, Rosso-Fernandez C, Morales IM, Palacios-Baena ZR, Hernández-Torres A, Merino de Lucas E, Escolà-Vergé L, Bereciartua E, García-Vázquez E, Pintado V, Boix-Palop L, Natera-Kindelán C, Sorlí L, Borrell N, Giner-Oncina L, Amador-Prous C, Shaw E, Jover-Saenz A, Molina J, Martínez-Alvarez RM, Dueñas CJ, Calvo-Montes J, Silva JT, Cárdenes MA, Lecuona M, Pomar V, Valiente de Santis L, Yagüe-Guirao G, Lobo-Acosta MA, Merino-Bohórquez V, Pascual A, Rodríguez-Baño J; REIPI-GEIRAS-FOREST group
JAMA Netw Open 2022 Jan 4;5(1):e2137277. doi: 10.1001/jamanetworkopen.2021.37277. PMID: 35024838Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Gaastra W, Kusters JG, van Duijkeren E, Lipman LJ
Vet Microbiol 2014 Aug 6;172(1-2):7-12. Epub 2014 May 9 doi: 10.1016/j.vetmic.2014.04.016. PMID: 24861842

Prognosis

Stoll BJ, Puopolo KM, Hansen NI, Sánchez PJ, Bell EF, Carlo WA, Cotten CM, D'Angio CT, Kazzi SNJ, Poindexter BB, Van Meurs KP, Hale EC, Collins MV, Das A, Baker CJ, Wyckoff MH, Yoder BA, Watterberg KL, Walsh MC, Devaskar U, Laptook AR, Sokol GM, Schrag SJ, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA Pediatr 2020 Jul 1;174(7):e200593. Epub 2020 Jul 6 doi: 10.1001/jamapediatrics.2020.0593. PMID: 32364598Free PMC Article
Giordano M, Baldassarre ME, Palmieri V, Torres DD, Carbone V, Santangelo L, Gentile F, Panza R, Di Mauro F, Capozza M, Di Mauro A, Laforgia N
Int J Environ Res Public Health 2019 May 12;16(9) doi: 10.3390/ijerph16091649. PMID: 31083597Free PMC Article
Tan CW, Chlebicki MP
Singapore Med J 2016 Sep;57(9):485-90. doi: 10.11622/smedj.2016153. PMID: 27662890Free PMC Article
Davis TK, Van De Kar NCAJ, Tarr PI
Microbiol Spectr 2014 Aug;2(4):EHEC-0025-2014. doi: 10.1128/microbiolspec.EHEC-0025-2014. PMID: 26104210
Page AV, Liles WC
Med Clin North Am 2013 Jul;97(4):681-95, xi. doi: 10.1016/j.mcna.2013.04.001. PMID: 23809720

Clinical prediction guides

Zhou Y, Zhou Z, Zheng L, Gong Z, Li Y, Jin Y, Huang Y, Chi M
Int J Mol Sci 2023 Jun 23;24(13) doi: 10.3390/ijms241310537. PMID: 37445714Free PMC Article
Leung AKC, Wong AHC, Leung AAM, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):2-18. doi: 10.2174/1872213X13666181228154940. PMID: 30592257Free PMC Article
Lima AAM, Medeiros PHQS, Havt A
Curr Opin Infect Dis 2018 Oct;31(5):433-439. doi: 10.1097/QCO.0000000000000477. PMID: 30063473
Tandogdu Z, Wagenlehner FM
Curr Opin Infect Dis 2016 Feb;29(1):73-9. doi: 10.1097/QCO.0000000000000228. PMID: 26694621
Manges AR
Clin Microbiol Infect 2016 Feb;22(2):122-129. Epub 2015 Dec 8 doi: 10.1016/j.cmi.2015.11.010. PMID: 26679924

Recent systematic reviews

Williams G, Hahn D, Stephens JH, Craig JC, Hodson EM
Cochrane Database Syst Rev 2023 Apr 17;4(4):CD001321. doi: 10.1002/14651858.CD001321.pub6. PMID: 37068952Free PMC Article
Raoofi S, Pashazadeh Kan F, Rafiei S, Hosseinipalangi Z, Noorani Mejareh Z, Khani S, Abdollahi B, Seyghalani Talab F, Sanaei M, Zarabi F, Dolati Y, Ahmadi N, Raoofi N, Sarhadi Y, Masoumi M, Sadat Hosseini B, Vali N, Gholamali N, Asadi S, Ahmadi S, Ahmadi B, Beiramy Chomalu Z, Asadollahi E, Rajabi M, Gharagozloo D, Nejatifar Z, Soheylirad R, Jalali S, Aghajani F, Navidriahy M, Deylami S, Nasiri M, Zareei M, Golmohammadi Z, Shabani H, Torabi F, Shabaninejad H, Nemati A, Amerzadeh M, Aryankhesal A, Ghashghaee A
PLoS One 2023;18(1):e0274248. Epub 2023 Jan 27 doi: 10.1371/journal.pone.0274248. PMID: 36706112Free PMC Article
Cooper TE, Teng C, Howell M, Teixeira-Pinto A, Jaure A, Wong G
Cochrane Database Syst Rev 2022 Aug 30;8(8):CD013608. doi: 10.1002/14651858.CD013608.pub2. PMID: 36041061Free PMC Article
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Bonten M, Johnson JR, van den Biggelaar AHJ, Georgalis L, Geurtsen J, de Palacios PI, Gravenstein S, Verstraeten T, Hermans P, Poolman JT
Clin Infect Dis 2021 Apr 8;72(7):1211-1219. doi: 10.1093/cid/ciaa210. PMID: 32406495

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