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t(4;14)

MedGen UID:
459168
Concept ID:
C2986942
Cell or Molecular Dysfunction

Definition

A chromosomal translocation that involves the chromosomes 4 and 14. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(4;14)

Professional guidelines

PubMed

Rajkumar SV
Am J Hematol 2024 Sep;99(9):1802-1824. Epub 2024 Jun 28 doi: 10.1002/ajh.27422. PMID: 38943315Free PMC Article
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762

Recent clinical studies

Etiology

Rajkumar SV
Am J Hematol 2024 Sep;99(9):1802-1824. Epub 2024 Jun 28 doi: 10.1002/ajh.27422. PMID: 38943315Free PMC Article
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Hanamura I
Int J Hematol 2022 Jun;115(6):762-777. Epub 2022 May 9 doi: 10.1007/s12185-022-03353-5. PMID: 35534749Free PMC Article
Rajkumar SV, Kumar S
Blood Cancer J 2020 Sep 28;10(9):94. doi: 10.1038/s41408-020-00359-2. PMID: 32989217Free PMC Article
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178

Diagnosis

Rajkumar SV
Am J Hematol 2024 Sep;99(9):1802-1824. Epub 2024 Jun 28 doi: 10.1002/ajh.27422. PMID: 38943315Free PMC Article
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Hanamura I
Int J Hematol 2022 Jun;115(6):762-777. Epub 2022 May 9 doi: 10.1007/s12185-022-03353-5. PMID: 35534749Free PMC Article
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178

Therapy

Rajkumar SV
Am J Hematol 2024 Sep;99(9):1802-1824. Epub 2024 Jun 28 doi: 10.1002/ajh.27422. PMID: 38943315Free PMC Article
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Hanamura I
Int J Hematol 2022 Jun;115(6):762-777. Epub 2022 May 9 doi: 10.1007/s12185-022-03353-5. PMID: 35534749Free PMC Article
Goel U, Usmani S, Kumar S
Am J Hematol 2022 May;97 Suppl 1:S3-S25. Epub 2022 Mar 10 doi: 10.1002/ajh.26512. PMID: 35234302
Rajkumar SV, Kumar S
Blood Cancer J 2020 Sep 28;10(9):94. doi: 10.1038/s41408-020-00359-2. PMID: 32989217Free PMC Article

Prognosis

D'Agostino M, Cairns DA, Lahuerta JJ, Wester R, Bertsch U, Waage A, Zamagni E, Mateos MV, Dall'Olio D, van de Donk NWCJ, Jackson G, Rocchi S, Salwender H, Bladé Creixenti J, van der Holt B, Castellani G, Bonello F, Capra A, Mai EK, Dürig J, Gay F, Zweegman S, Cavo M, Kaiser MF, Goldschmidt H, Hernández Rivas JM, Larocca A, Cook G, San-Miguel JF, Boccadoro M, Sonneveld P
J Clin Oncol 2022 Oct 10;40(29):3406-3418. Epub 2022 May 23 doi: 10.1200/JCO.21.02614. PMID: 35605179
Hanamura I
Int J Hematol 2022 Jun;115(6):762-777. Epub 2022 May 9 doi: 10.1007/s12185-022-03353-5. PMID: 35534749Free PMC Article
Rajkumar SV, Kumar S
Blood Cancer J 2020 Sep 28;10(9):94. doi: 10.1038/s41408-020-00359-2. PMID: 32989217Free PMC Article
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178
Palumbo A, Avet-Loiseau H, Oliva S, Lokhorst HM, Goldschmidt H, Rosinol L, Richardson P, Caltagirone S, Lahuerta JJ, Facon T, Bringhen S, Gay F, Attal M, Passera R, Spencer A, Offidani M, Kumar S, Musto P, Lonial S, Petrucci MT, Orlowski RZ, Zamagni E, Morgan G, Dimopoulos MA, Durie BG, Anderson KC, Sonneveld P, San Miguel J, Cavo M, Rajkumar SV, Moreau P
J Clin Oncol 2015 Sep 10;33(26):2863-9. Epub 2015 Aug 3 doi: 10.1200/JCO.2015.61.2267. PMID: 26240224Free PMC Article

Clinical prediction guides

Kaiser MF, Hall A, Walker K, Sherborne A, De Tute RM, Newnham N, Roberts S, Ingleson E, Bowles K, Garg M, Lokare A, Messiou C, Houlston RS, Jackson G, Cook G, Pratt G, Owen RG, Drayson MT, Brown SR, Jenner MW
J Clin Oncol 2023 Aug 10;41(23):3945-3955. Epub 2023 Jun 14 doi: 10.1200/JCO.22.02567. PMID: 37315268
D'Agostino M, Cairns DA, Lahuerta JJ, Wester R, Bertsch U, Waage A, Zamagni E, Mateos MV, Dall'Olio D, van de Donk NWCJ, Jackson G, Rocchi S, Salwender H, Bladé Creixenti J, van der Holt B, Castellani G, Bonello F, Capra A, Mai EK, Dürig J, Gay F, Zweegman S, Cavo M, Kaiser MF, Goldschmidt H, Hernández Rivas JM, Larocca A, Cook G, San-Miguel JF, Boccadoro M, Sonneveld P
J Clin Oncol 2022 Oct 10;40(29):3406-3418. Epub 2022 May 23 doi: 10.1200/JCO.21.02614. PMID: 35605179
Hanamura I
Int J Hematol 2022 Jun;115(6):762-777. Epub 2022 May 9 doi: 10.1007/s12185-022-03353-5. PMID: 35534749Free PMC Article
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762
Mateos MV, Kumar S, Dimopoulos MA, González-Calle V, Kastritis E, Hajek R, De Larrea CF, Morgan GJ, Merlini G, Goldschmidt H, Geraldes C, Gozzetti A, Kyriakou C, Garderet L, Hansson M, Zamagni E, Fantl D, Leleu X, Kim BS, Esteves G, Ludwig H, Usmani S, Min CK, Qi M, Ukropec J, Weiss BM, Rajkumar SV, Durie BGM, San-Miguel J
Blood Cancer J 2020 Oct 16;10(10):102. doi: 10.1038/s41408-020-00366-3. PMID: 33067414Free PMC Article

Recent systematic reviews

He W, He F, Hu H
Ann Med 2023 Dec;55(1):1029-1036. doi: 10.1080/07853890.2023.2186480. PMID: 36911885Free PMC Article
Giri S, Grimshaw A, Bal S, Godby K, Kharel P, Djulbegovic B, Dimopoulos MA, Facon T, Usmani SZ, Mateos MV, Costa LJ
JAMA Oncol 2020 Nov 1;6(11):1759-1765. doi: 10.1001/jamaoncol.2020.4338. PMID: 32970151Free PMC Article

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