U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Blount disease, adolescent

MedGen UID:
462922
•Concept ID:
C3151572
•
Disease or Syndrome
Synonyms: OSTEOCHONDROSIS DEFORMANS TIBIAE, ADOLESCENT; TIBIA VARA, ADOLESCENT
 
Monarch Initiative: MONDO:0009800
OMIM®: 259200

Definition

Blount disease is a developmental condition characterized by disordered endochondral ossification of the medial part of the proximal tibial physis resulting in multiplanar deformities of the lower limb (review by Sabharwal, 2009). [from OMIM]

Clinical features

From HPO
Genu varum
MedGen UID:
154257
•Concept ID:
C0544755
•
Finding
A positional abnormality marked by outward bowing of the legs in which the knees stay wide apart when a person stands with the feet and ankles together.
See: Feature record | Search on this feature
Osteochondritis dissecans
MedGen UID:
10494
•Concept ID:
C0029421
•
Disease or Syndrome
A joint disorder caused by blood deprivation in the subchondral bone causing the subchondral bone to die in a process called avascular necrosis. The bone is then reabsorbed by the body, leaving the articular cartilage it supported prone to damage. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these osteochondral fragments within the joint space, causing pain and further damage.
See: Feature record | Search on this feature
Bowing of the legs
MedGen UID:
1807399
•Concept ID:
C5574706
•
Finding
A bending or abnormal curvature affecting a long bone of the leg.
See: Feature record | Search on this feature
Show allHide all

Professional guidelines

PubMed

Update on treatment of adolescent Blount disease.
de Pablos J, Arbeloa-Gutierrez L, Arenas-Miquelez A
Curr Opin Pediatr 2018 Feb;30(1):71-77. doi: 10.1097/MOP.0000000000000569. PMID: 29315109
Treatment of Adolescent Blount Disease Using Taylor Spatial Frame With and Without Fibular Osteotomy: Is There any Difference?
Sachs O, Katzman A, Abu-Johar E, Eidelman M
J Pediatr Orthop 2015 Jul-Aug;35(5):501-6. doi: 10.1097/BPO.0000000000000317. PMID: 25321881

Recent clinical studies

Etiology

Clinical and Radiographic Assessment of Adult Function After Blount Disease in Childhood: An Exercise in Futility.
Makarov MR, Polk JL, Shivers CR, Jo CH, Rathjen KE, Birch JG
J Pediatr Orthop 2023 Oct 1;43(9):e757-e760. Epub 2023 Jul 24 doi: 10.1097/BPO.0000000000002482. PMID: 37493033
Gradual correction of proximal tibia deformity for Blount disease in adolescent and young adults.
Saw A, Phang ZH, Alrasheed MK, Gunalan R, Albaker MZ, Shanmugam R
J Orthop Surg (Hong Kong) 2019 Sep-Dec;27(3):2309499019873987. doi: 10.1177/2309499019873987. PMID: 31530084
Radiography, CT, and MRI of Hip and Lower Limb Disorders in Children and Adolescents.
Silva MS, Fernandes ARC, Cardoso FN, Longo CH, Aihara AY
Radiographics 2019 May-Jun;39(3):779-794. doi: 10.1148/rg.2019180101. PMID: 31059403
Gradual Deformity Correction in Blount Disease.
Mayer SW, Hubbard EW, Sun D, Lark RK, Fitch RD
J Pediatr Orthop 2019 May/Jun;39(5):257-262. doi: 10.1097/BPO.0000000000000920. PMID: 30969256
Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866

Diagnosis

Radiography, CT, and MRI of Hip and Lower Limb Disorders in Children and Adolescents.
Silva MS, Fernandes ARC, Cardoso FN, Longo CH, Aihara AY
Radiographics 2019 May-Jun;39(3):779-794. doi: 10.1148/rg.2019180101. PMID: 31059403
Gradual Deformity Correction in Blount Disease.
Mayer SW, Hubbard EW, Sun D, Lark RK, Fitch RD
J Pediatr Orthop 2019 May/Jun;39(5):257-262. doi: 10.1097/BPO.0000000000000920. PMID: 30969256
Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Blount disease: an update.
Sabharwal S
Orthop Clin North Am 2015 Jan;46(1):37-47. Epub 2014 Oct 12 doi: 10.1016/j.ocl.2014.09.002. PMID: 25435033
Blount disease.
Birch JG
J Am Acad Orthop Surg 2013 Jul;21(7):408-18. doi: 10.5435/JAAOS-21-07-408. PMID: 23818028

Therapy

Tension Band Plate (TBP)-guided Hemiepiphysiodesis in Blount Disease: 10-Year Single-center Experience With a Systematic Review of Literature.
Jain MJ, Inneh IA, Zhu H, Phillips WA
J Pediatr Orthop 2020 Feb;40(2):e138-e143. doi: 10.1097/BPO.0000000000001393. PMID: 31022017
Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery.
Bout-Tabaku S, Gupta R, Jenkins TM, Ryder JR, Baughcum AE, Jackson RD, Inge TH, Dixon JB, Helmrath MA, Courcoulas AP, Mitchell JE, Harmon CM, Xie C, Michalsky MP; TEEN-LABS CONSORTIUM
Pediatrics 2019 Dec;144(6) Epub 2019 Nov 19 doi: 10.1542/peds.2019-1399. PMID: 31744891Free PMC Article
Treatment of Infantile Blount Disease: An Update.
Sabharwal S, Sabharwal S
J Pediatr Orthop 2017 Sep;37 Suppl 2:S26-S31. doi: 10.1097/BPO.0000000000001027. PMID: 28799991
Spectrum of paediatric rheumatic diseases in Nigeria.
Olaosebikan BH, Adelowo OO, Animashaun BA, Akintayo RO
Pediatr Rheumatol Online J 2017 Jan 31;15(1):7. doi: 10.1186/s12969-017-0139-3. PMID: 28143550Free PMC Article
Treatment of Adolescent Blount Disease Using Taylor Spatial Frame With and Without Fibular Osteotomy: Is There any Difference?
Sachs O, Katzman A, Abu-Johar E, Eidelman M
J Pediatr Orthop 2015 Jul-Aug;35(5):501-6. doi: 10.1097/BPO.0000000000000317. PMID: 25321881

Prognosis

Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Opening Wedge Osteotomy for the Correction of Adolescent Tibia Vara.
Griswold B, Gilbert S, Khoury J
Iowa Orthop J 2018;38:141-146. PMID: 30104937Free PMC Article
Guided growth for tibia vara (Blount's disease).
Heflin JA, Ford S, Stevens P
Medicine (Baltimore) 2016 Oct;95(41):e4951. doi: 10.1097/MD.0000000000004951. PMID: 27741108Free PMC Article
Treatment of Blount disease: a comparison between the multiaxial correction system and other external fixators.
Clarke SE, McCarthy JJ, Davidson RS
J Pediatr Orthop 2009 Mar;29(2):103-9. doi: 10.1097/BPO.0b013e3181982a62. PMID: 19352232
Blount disease: a review of the English literature.
Bradway JK, Klassen RA, Peterson HA
J Pediatr Orthop 1987 Jul-Aug;7(4):472-80. PMID: 3301898

Clinical prediction guides

Clinical and Radiographic Assessment of Adult Function After Blount Disease in Childhood: An Exercise in Futility.
Makarov MR, Polk JL, Shivers CR, Jo CH, Rathjen KE, Birch JG
J Pediatr Orthop 2023 Oct 1;43(9):e757-e760. Epub 2023 Jul 24 doi: 10.1097/BPO.0000000000002482. PMID: 37493033
Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Spectrum of paediatric rheumatic diseases in Nigeria.
Olaosebikan BH, Adelowo OO, Animashaun BA, Akintayo RO
Pediatr Rheumatol Online J 2017 Jan 31;15(1):7. doi: 10.1186/s12969-017-0139-3. PMID: 28143550Free PMC Article
Blount disease.
Birch JG
J Am Acad Orthop Surg 2013 Jul;21(7):408-18. doi: 10.5435/JAAOS-21-07-408. PMID: 23818028
Blount disease: a review of the English literature.
Bradway JK, Klassen RA, Peterson HA
J Pediatr Orthop 1987 Jul-Aug;7(4):472-80. PMID: 3301898

Recent systematic reviews

Tension Band Plate (TBP)-guided Hemiepiphysiodesis in Blount Disease: 10-Year Single-center Experience With a Systematic Review of Literature.
Jain MJ, Inneh IA, Zhu H, Phillips WA
J Pediatr Orthop 2020 Feb;40(2):e138-e143. doi: 10.1097/BPO.0000000000001393. PMID: 31022017

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • OMIM
      Related records in OMIM
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...