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Diplegia

MedGen UID:
472941
Concept ID:
C0221165
Disease or Syndrome
Synonym: Bilateral paralysis
SNOMED CT: Diplegia (6481005); Bilateral paralysis (6481005)

Definition

Paralysis affecting corresponding parts on both sides of the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiplegia

Professional guidelines

PubMed

Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Nicolini-Panisson RD, Tedesco AP, Folle MR, Donadio MVF
Rev Paul Pediatr 2018 Jan-Mar;36(1):9. Epub 2018 Jan 15 doi: 10.1590/1984-0462/;2018;36;1;00005. PMID: 29412426Free PMC Article
Aiona MD, Sussman MD
J Pediatr Orthop B 2004 May;13(3):S13-38. doi: 10.1097/00009957-200405000-00016. PMID: 15083127

Recent clinical studies

Etiology

Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Arvedson JC
Eur J Clin Nutr 2013 Dec;67 Suppl 2:S9-12. doi: 10.1038/ejcn.2013.224. PMID: 24301008
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Kelly IP, Jenkinson A, Stephens M, O'Brien T
J Pediatr Orthop 1997 Jul-Aug;17(4):478-80. PMID: 9364387

Diagnosis

Sinibaldi L, Garone G, Mandarino A, Iarossi G, Chioma L, Dentici ML, Merla G, Agolini E, Micalizzi A, Mancini C, Niceta M, Macchiaiolo M, Diodato D, Onesimo R, Blandino R, Delogu AB, De Rosa G, Trevisan V, Iademarco M, Zampino G, Tartaglia M, Novelli A, Bartuli A, Digilio MC, Calcagni G
Clin Genet 2023 Nov;104(5):528-541. Epub 2023 Jul 17 doi: 10.1111/cge.14404. PMID: 37455656
Ebrahimi-Fakhari D, Saffari A, Pearl PL
Mol Genet Metab 2022 Dec;137(4):436-444. Epub 2021 Jun 24 doi: 10.1016/j.ymgme.2021.06.006. PMID: 34183250Free PMC Article
Huntsman R, Lemire E, Norton J, Dzus A, Blakley P, Hasal S
Arch Dis Child 2015 May;100(5):500-4. Epub 2014 Nov 18 doi: 10.1136/archdischild-2014-307443. PMID: 25700542
des Portes V
Handb Clin Neurol 2013;111:297-306. doi: 10.1016/B978-0-444-52891-9.00035-X. PMID: 23622180
Dutra LA, Braga-Neto P, Pedroso JL, Povoas Barsottini OG
Adv Exp Med Biol 2012;724:344-50. doi: 10.1007/978-1-4614-0653-2_26. PMID: 22411255

Therapy

Menon J, Shanmugam N, Rammohan A, Hakeem A, Reddy MS, Rela M
Pediatr Transplant 2022 Dec;26(8):e14376. Epub 2022 Aug 12 doi: 10.1111/petr.14376. PMID: 35959774
Matusiak-Wieczorek E, Dziankowska-Zaborszczyk E, Synder M, Borowski A
Int J Environ Res Public Health 2020 Sep 19;17(18) doi: 10.3390/ijerph17186846. PMID: 32961681Free PMC Article
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Biotti D, Vignal C, Sharshar T, Gout O, McCoy AN, Miller NR
Surv Ophthalmol 2012 Nov;57(6):565-72. Epub 2012 Mar 6 doi: 10.1016/j.survophthal.2011.10.002. PMID: 22398335

Prognosis

Menon J, Shanmugam N, Rammohan A, Hakeem A, Reddy MS, Rela M
Pediatr Transplant 2022 Dec;26(8):e14376. Epub 2022 Aug 12 doi: 10.1111/petr.14376. PMID: 35959774
Warrack S, Love T, Rizzo WB
J Child Neurol 2021 Oct;36(11):1011-1016. Epub 2021 Jul 28 doi: 10.1177/08830738211029390. PMID: 34315315Free PMC Article
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Cho KH, Shim SH, Kim M
Clin Genet 2018 Apr;93(4):721-730. Epub 2017 Sep 17 doi: 10.1111/cge.13058. PMID: 28543186
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151

Clinical prediction guides

K A, Saini L, Gunasekaran PK, Singh P, Sahu JK, Sankhyan N, Sharma R, Bhati A, Yadav J, Sharawat IK
Seizure 2022 Oct;101:190-196. Epub 2022 Aug 24 doi: 10.1016/j.seizure.2022.08.009. PMID: 36070632
Menon J, Shanmugam N, Rammohan A, Hakeem A, Reddy MS, Rela M
Pediatr Transplant 2022 Dec;26(8):e14376. Epub 2022 Aug 12 doi: 10.1111/petr.14376. PMID: 35959774
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Dooley JM, Stewart WA, Hayden JD, Therrien A
Pediatr Neurol 2004 Jan;30(1):39-41. doi: 10.1016/s0887-8994(03)00408-9. PMID: 14738949

Recent systematic reviews

Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Guinet AL, Khouri N, Desailly E
Am J Phys Med Rehabil 2022 Apr 1;101(4):389-399. doi: 10.1097/PHM.0000000000001864. PMID: 34393188
Villegas-López FA, Armas-Salazar A, Beltrán JQ, Téllez-León N, Arellano-Alcántara A, Navarro-Olvera JL, Carrillo-Ruiz JD
Stereotact Funct Neurosurg 2021;99(6):521-525. Epub 2021 Jun 9 doi: 10.1159/000516423. PMID: 34107470
Reid SM, Carlin JB, Reddihough DS
Res Dev Disabil 2011 Nov-Dec;32(6):2909-15. Epub 2011 May 31 doi: 10.1016/j.ridd.2011.05.012. PMID: 21624819

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