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Diplegia

MedGen UID:
472941
•Concept ID:
C0221165
•
Disease or Syndrome
Synonym: Bilateral paralysis
SNOMED CT: Diplegia (6481005); Bilateral paralysis (6481005)

Definition

Paralysis affecting corresponding parts on both sides of the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiplegia

Professional guidelines

PubMed

Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
SELECTIVE DORSAL RHIZOTOMY IN CEREBRAL PALSY: SELECTION CRITERIA AND POSTOPERATIVE PHYSICAL THERAPY PROTOCOLS.
Nicolini-Panisson RD, Tedesco AP, Folle MR, Donadio MVF
Rev Paul Pediatr 2018 Jan-Mar;36(1):9. Epub 2018 Jan 15 doi: 10.1590/1984-0462/;2018;36;1;00005. PMID: 29412426Free PMC Article
The differential diagnosis of spastic diplegia.
Huntsman R, Lemire E, Norton J, Dzus A, Blakley P, Hasal S
Arch Dis Child 2015 May;100(5):500-4. Epub 2014 Nov 18 doi: 10.1136/archdischild-2014-307443. PMID: 25700542

Recent clinical studies

Therapy

Association of Guillain-Barré syndrome following COVID-19 vaccination.
Chowdhury S, Chowdhury S
Int J Immunopathol Pharmacol 2023 Jan-Dec;37:3946320231199349. doi: 10.1177/03946320231199349. PMID: 37681361Free PMC Article
The Influence of Hippotherapy on the Body Posture in a Sitting Position among Children with Cerebral Palsy.
Matusiak-Wieczorek E, Dziankowska-Zaborszczyk E, Synder M, Borowski A
Int J Environ Res Public Health 2020 Sep 19;17(18) doi: 10.3390/ijerph17186846. PMID: 32961681Free PMC Article
Effect of simultaneous proprioceptive-visual feedback on gait of children with spastic diplegic cerebral palsy.
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Cerebral folate deficiency.
Hyland K, Shoffner J, Heales SJ
J Inherit Metab Dis 2010 Oct;33(5):563-70. Epub 2010 Jul 29 doi: 10.1007/s10545-010-9159-6. PMID: 20668945

Prognosis

Molybdenum cofactor deficiency: A natural history.
Spiegel R, Schwahn BC, Squires L, Confer N
J Inherit Metab Dis 2022 May;45(3):456-469. Epub 2022 Mar 3 doi: 10.1002/jimd.12488. PMID: 35192225Free PMC Article
Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Clinical, biochemical, and genetic aspects of Sjögren-Larsson syndrome.
Cho KH, Shim SH, Kim M
Clin Genet 2018 Apr;93(4):721-730. Epub 2017 Sep 17 doi: 10.1111/cge.13058. PMID: 28543186
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Cerebral palsy.
Dabney KW, Lipton GE, Miller F
Curr Opin Pediatr 1997 Feb;9(1):81-8. doi: 10.1097/00008480-199702000-00017. PMID: 9088760

Clinical prediction guides

Association of Guillain-Barré syndrome following COVID-19 vaccination.
Chowdhury S, Chowdhury S
Int J Immunopathol Pharmacol 2023 Jan-Dec;37:3946320231199349. doi: 10.1177/03946320231199349. PMID: 37681361Free PMC Article
Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Congenital and infantile myotonic dystrophy.
Echenne B, Bassez G
Handb Clin Neurol 2013;113:1387-93. doi: 10.1016/B978-0-444-59565-2.00009-5. PMID: 23622362
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability.
Eliasson AC, Krumlinde-Sundholm L, Rösblad B, Beckung E, Arner M, Ohrvall AM, Rosenbaum P
Dev Med Child Neurol 2006 Jul;48(7):549-54. doi: 10.1017/S0012162206001162. PMID: 16780622

Recent systematic reviews

Effects of Hippotherapy on Postural Control in Children With Cerebral Palsy: A Systematic Review.
Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Perinatal and long-term outcome of fetal intracranial hemorrhage: systematic review and meta-analysis.
Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Guillain-Barré syndrome associated with SARS-CoV-2 infection: a scoping review.
Medeiros KS, Macêdo LTA, Souza WF, Sarmento AC, Costa APF, Gonçalves AK
Rev Assoc Med Bras (1992) 2021 Feb;67(2):318-334. doi: 10.1590/1806-9282.67.2.20200716. PMID: 34406260
Classification of topographical pattern of spasticity in cerebral palsy: a registry perspective.
Reid SM, Carlin JB, Reddihough DS
Res Dev Disabil 2011 Nov-Dec;32(6):2909-15. Epub 2011 May 31 doi: 10.1016/j.ridd.2011.05.012. PMID: 21624819
A systematic review of the effectiveness of aerobic exercise interventions for children with cerebral palsy: an AACPDM evidence report.
Rogers A, Furler BL, Brinks S, Darrah J
Dev Med Child Neurol 2008 Nov;50(11):808-14. Epub 2008 Sep 22 doi: 10.1111/j.1469-8749.2008.03134.x. PMID: 18811714

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