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Non-Neoplastic Nervous System Disorder

MedGen UID:: 235384
•Concept ID:: C1335024
•: Disease or Syndrome

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNon-Neoplastic Nervous System Disorder

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of nervous system
        Non-Neoplastic Nervous System Disorder
        Abnormality of the nervous system
        Abnormal nervous system morphology
        Abnormal ganglion morphology
        Abnormal glial cell morphology
        Abnormal myelination
        Abnormal neuron morphology
        Abnormal peripheral nervous system morphology
        Morphological central nervous system abnormality
        Neoplasm of the nervous system
        Abnormal nervous system physiology
        Abnormal central motor function
        Abnormal central sensory function
        Abnormal cranial nerve physiology
        Abnormal hypothalamus physiology
        Abnormal nervous system electrophysiology
        Abnormal spinal cord physiology
        Abnormal synaptic transmission
        Abnormality of intracranial pressure
        Abnormality of mental function
        Abnormality of the sense of smell
        Autonomic-voluntary dissociation of facial movements
        Brain imaging abnormality
        Bulbar palsy
        Bulbar signs
        Easy fatigability
        Encephalopathy
        Headache
        Hypocalcemic tetany
        Lhermitte sign
        Movement disorder
        Neurodevelopmental abnormality
        Peripheral neuropathy
        Perisylvian FDG hypermetabolism
        Pseudobulbar signs
        Seizure
        Somatic sensory dysfunction
        Abnormality of neuronal migration
        Classical Lissencephalies and Subcortical Band Heterotopias
        Cobblestone lissencephaly
        Gray matter heterotopia
        Lissencephaly
        Periventricular nodular heterotopia
        Abnormality of the peripheral nervous system
        Abnormal peripheral nervous system physiology
        Abnormality of the autonomic nervous system
        Abnormality of the somatic nervous system
        Central nervous system cyst
        Arachnoid cyst
        Central Nervous System Colloid Cyst
        Central Nervous System Epidermoid Cyst
        Cerebral cyst
        Choroid plexus cyst
        Colloid cyst
        Endodermal Cyst
        Ependymal cyst
        Intracranial Colloid Cyst
        Intracranial cystic lesion
        Intraspinal Cyst
        Meningeal cyst
        Neurenteric cyst
        Perineural cyst
        Pineal cyst
        Pituitary gland cyst
        Rathke pouch cyst
        Cerebellar hypoplasia
        Cerebellar hemisphere hypoplasia
        Congenital facial nerve palsy
        Congenital hydrocephalus
        Congenital communicating hydrocephalus
        Congenital non-communicating hydrocephalus
        Hydrocephalus, congenital, 3, with brain anomalies
        Hydrocephalus, nonsyndromic, autosomal recessive 1
        Hydrocephalus, nonsyndromic, autosomal recessive 2
        Congenital meningocele
        Congenital cerebral meningocele
        Congenital spinal meningocele
        Corpus callosum, agenesis of
        Acrocallosal syndrome
        Aicardi syndrome
        Holoprosencephaly sequence
        Partial agenesis of the corpus callosum
        Septo-optic dysplasia sequence
        Craniorachischisis
        Dandy-Walker syndrome
        Isolated Dandy-Walker malformation with hydrocephalus
        Isolated Dandy-Walker malformation without hydrocephalus
        Diastematomyelia
        Encephalocele
        Anterior encephalocele
        Basal encephalocele
        Cranium bifidum occultum
        Meningoencephalocele
        Occipital encephalocele
        Parietal encephalocele
        Hereditary motor and sensory neuropathy
        Alstrom syndrome
        Charcot-Marie-Tooth disease
        Giant axonal neuropathy
        Hereditary spastic paraplegia
        Phytanic acid storage disease
        Hereditary Neurodegenerative Disorder
        Neurodegeneration with brain iron accumulation 4
        Neurodegeneration with brain iron accumulation 5
        Hereditary sensory and autonomic neuropathy
        Congenital insensitivity to pain with hyperhidrosis
        Familial dysautonomia
        X-linked hereditary sensory and autonomic neuropathy with hearing loss
        Hydranencephaly
        Malformation of cortical development
        Malformations of Cortical Development, Group I
        Malformations of Cortical Development, Group III
        Subcortical band heterotopia
        microgyria
        Myelocele
        Cervical myelocele
        Lumbar myelocele
        Sacral Myelocele
        Thoracic myelocele
        Neural tube defect
        Anencephaly
        Cephalocele
        Chiari malformation
        Closed neural tube defect
        Holorachischisis
        Iniencephaly
        Meningohydroencephalocele
        Myelomeningocele
        Neural tube defects, susceptibility to
        Open neural tube defect
        Pentalogy of Cantrell
        Spina bifida
        Spinal dysraphism
        Non-ketotic hyperglycinemia
        Atypical glycine encephalopathy
        Infantile glycine encephalopathy
        Neonatal glycine encephalopathy
        Optic nerve hypoplasia
        Isolated optic nerve hypoplasia
        Unilateral Optic Nerve Hypoplasia
        Polymicrogyria
        Bilateral frontoparietal polymicrogyria
        Bilateral polymicrogyria
        Focal polymicrogyria
        Frontal polymicrogyria
        Parasagittal parieto-occipital polymicrogyria
        Perisylvian polymicrogyria
        Unilateral polymicrogyria
        Schizencephaly
        Acquired schizencephaly
        Familial schizencephaly
        Type 1 schizencephaly
        Type 2 schizencephaly
        Type 3 schizencephaly
        Vascular malformation of the nervous system
        Arteriovenous Malformation, Intracranial
        Central Nervous System Cavernous Hemangioma
        Central Nervous System Venous Angioma
        Cerebral arteriovenous malformation
        Cerebral cavernous malformation
        Meningioangiomatosis
        Sinus pericranii
        Vein of Galen malformation
        Autoimmune disorder of the nervous system
        Anti-NMDA receptor encephalitis
        Central nervous system lupus
        Central nervous system vasculitis
        Central nervous system AIDS arteritis
        Giant cell arteritis
        CNS demyelinating autoimmune disease
        Acute disseminated encephalomyelitis
        Acute hemorrhagic leukoencephalitis
        Multiple sclerosis
        Neuromyelitis optica
        Schilder disease
        Transverse myelitis
        Guillain-Barre syndrome
        Acute inflammatory demyelinating polyradiculoneuropathy
        Acute motor and sensory axonal neuropathy
        Acute motor axonal neuropathy
        Miller Fisher syndrome
        Myasthenia gravis
        Adult-onset myasthenia gravis
        Eaton-Lambert syndrome
        Juvenile myasthenia gravis
        Neonatal myasthenia gravis
        Transient neonatal myasthenia gravis
        Polyradiculoneuropathy
        Cauda equina syndrome
        Chronic inflammatory demyelinating polyradiculoneuropathy
        Polyradiculopathy
        Steroid-responsive encephalopathy associated with autoimmune thyroiditis
        Stiff-man syndrome
        Classic stiff person syndrome
        Focal stiff limb syndrome
        Progressive encephalomyelitis with rigidity and myoclonus
        Vogt-Koyanagi-Harada disease
        Demyelinating disease
        Central pontine myelinolysis
        Demyelinating disease of central nervous system
        Demyelinating Encephalopathy
        Demyelinating peripheral neuropathy
        Acute demyelinating polyneuropathy
        Demyelinating sensory neuropathy
        Hereditary Central Nervous System Demyelinating Diseases
        Adrenoleukodystrophy
        Alexander disease
        Galactosylceramide beta-galactosidase deficiency
        Metachromatic leukodystrophy
        Pelizaeus-Merzbacher disease
        Spongy degeneration of central nervous system
        Marchiafava-Bignami disease
        Progressive multifocal leukoencephalopathy
        Recurrent painful ophthalmoplegic neuropathy
        Subacute combined degeneration of spinal cord
        Infectious disease of the nervous system
        COVID-19-Associated Nervous System Disorder
        COVID-19-Associated Ataxia
        COVID-19-Associated Encephalitis
        COVID-19-Associated Stroke
        COVID-19-Associated Trigeminal Neuralgia
        HTLV-1-associated myelopathy-tropical spastic paraparesis
        Infection of cranial nerve
        Infectious disease of central nervous system
        Arachnoiditis
        Bacterial infection of central nervous system
        Brain abscess
        Cerebral abscess
        Cerebritis
        Encephalomyelitis
        Epidural abscess
        Fungal infection of central nervous system
        Infectious encephalitis
        Infectious meningitis
        Infectious Meningoencephalitis
        Leukoencephalopathy
        Meningoencephalitis
        Myelitis
        Parasitic infection of central nervous system
        Perimeningeal Infections
        Poliomyelitis
        Prion disease
        Viral infection of central nervous system
        Infectious disease with peripheral neuropathy
        Acute infective polyneuritis
        Geniculate herpes zoster
        Leprosy
        Lyme disease
        Meningococcal meningitis
        Waterhouse-Friderichsen Syndrome
        Pneumococcal meningitis
        Rabies
        Tetanus
        Tetanus neonatorum
        Tuberculosis of meninges
        Leukodystrophy
        Adult-onset autosomal dominant demyelinating leukodystrophy
        Aicardi Goutieres syndrome
        Aicardi-Goutieres syndrome 1
        Aicardi-Goutieres syndrome 2
        Aicardi-Goutieres syndrome 3
        Aicardi-Goutieres syndrome 4
        Aicardi-Goutieres syndrome 5
        Aicardi-Goutieres syndrome 6
        Alkaline ceramidase 3 deficiency
        C11orf73-related autosomal recessive hypomyelinating leukodystrophy
        CADDS
        Cavitating leukodystrophy
        Cholestanol storage disease
        Cystic leukoencephalopathy without megalencephaly
        Deficiency of ribose-5-phosphate isomerase
        Dermatoleukodystrophy
        Dysmyelinating leukodystrophy
        Early-onset calcifying leukoencephalopathy-skeletal dysplasia
        Hereditary spastic paraplegia 2
        Hypomyelinating leukodystrophy 6
        Hypomyelinating leukodystrophy 9
        Hypomyelinating leukodystrophy 12
        Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism
        Hypomyelination and Congenital Cataract
        Hypomyelination with brain stem and spinal cord involvement and leg spasticity
        Leukoencephalopathy with bilateral anterior temporal lobe cysts
        Leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome
        Leukoencephalopathy with mild cerebellar ataxia and white matter edema
        Leukoencephalopathy, diffuse hereditary, with spheroids 1
        Leukoencephalopathy-thalamus and brainstem anomalies-high lactate syndrome
        Megalencephalic leukoencephalopathy with subcortical cysts
        Megalencephalic leukoencephalopathy with subcortical cysts 1
        Megalencephalic leukoencephalopathy with subcortical cysts 2A
        Megalencephalic leukoencephalopathy with subcortical cysts 2B, remitting, with or without intellectual disability
        Multiple mitochondrial dysfunctions syndrome 4
        Neurodevelopmental disorder with microcephaly, epilepsy, and hypomyelination
        Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy
        PCWH syndrome
        Pelizaeus Merzbacher like disease
        Hypomyelinating leukodystrophy 2
        Hypomyelinating leukodystrophy 3
        Hypomyelinating leukodystrophy 4
        Peroxisome biogenesis disorder
        Peroxisome biogenesis disorder 1A (Zellweger)
        Peroxisome Biogenesis Disorder 1B
        Peroxisome biogenesis disorder 2A (Zellweger)
        Peroxisome biogenesis disorder 2B
        Peroxisome biogenesis disorder 3A (Zellweger)
        Peroxisome biogenesis disorder 4A (Zellweger)
        Peroxisome biogenesis disorder 4B
        Peroxisome biogenesis disorder 5A (Zellweger)
        Peroxisome biogenesis disorder 5B
        Peroxisome biogenesis disorder 6A (Zellweger)
        Peroxisome biogenesis disorder 6B
        Peroxisome biogenesis disorder 7A (Zellweger)
        Peroxisome biogenesis disorder 7B
        Peroxisome biogenesis disorder 8A (Zellweger)
        Peroxisome biogenesis disorder 8B
        Peroxisome biogenesis disorder type 3B
        Peroxisome Biogenesis Disorders in the Zellweger Spectrum
        Rhizomelic chondrodysplasia punctata
        Zellweger spectrum disorders
        POLR3-related leukodystrophy
        Hypomyelinating leukodystrophy 11
        Hypomyelination-cerebellar atrophy-hypoplasia of the corpus callosum syndrome
        Hypomyelination-hypogonadotropic hypogonadism-hypodontia syndrome
        Leukoencephalopathy-ataxia-hypodontia-hypomyelination syndrome
        Odontoleukodystrophy
        Tremor-ataxia-central hypomyelination syndrome
        Polycystic lipomembranous osteodysplasia with sclerosing leukoencephaly
        Progressive cavitating leukoencephalopathy
        Progressive encephalopathy with leukodystrophy due to DECR deficiency
        Ravine syndrome
        Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy
        Spondyloepimetaphyseal dysplasia, Bieganski type
        Spondyloepiphyseal dysplasia, sensorineural hearing loss, impaired intellectual development, and leber congenital amaurosis
        Sterol carrier protein 2 deficiency
        Vanishing white matter disease
        Congenital or early infantile CACH syndrome
        Juvenile or adult CACH syndrome
        Late infantile CACH syndrome
        Leukoencephalopathy with vanishing white matter 1
        Leukoencephalopathy with vanishing white matter 2
        Leukoencephalopathy with vanishing white matter 3
        Leukoencephalopathy with vanishing white matter 4
        Leukoencephalopathy with vanishing white matter 5
        Ovarioleukodystrophy
        Nerve palsy
        Cranial nerve paralysis
        Abducens nerve palsy
        Cranial Nerve II Palsy
        Facial paralysis
        Fourth cranial nerve palsy
        Glossopharyngeal nerve paralysis
        Hypoglossal nerve palsy
        Oculomotor nerve palsy
        Palsy of accessory nerve
        Palsy of vagus nerve
        Progressive bulbar palsy
        Trigeminal nerve palsy
        Vestibulocochlear nerve palsy
        Diplegia
        Laryngeal Nerve Paralysis
        Vagus nerve laryngeal paralysis
        Median Nerve Paralysis
        Monoplegia
        Paraplegia
        Brown-Séquard syndrome
        Spastic paraplegia
        Permanent Spinal Nerve Paralysis
        Peroneal nerve paralysis
        Phrenic nerve palsy
        Acquired Phrenic Nerve Palsy
        Congenital Phrenic Nerve Palsy
        Phrenic Nerve Palsy Related to Birth
        Tetraplegia
        Episodic quadriplegia
        Locked-in syndrome
        Neuronal intranuclear inclusion disease
        Non-Neoplastic Central Nervous System Disorder
        Alice in Wonderland syndrome
        Central Nervous System Hamartoma
        Hamartoma of brain
        Spinal Cord Hamartoma
        Degenerative disease of the central nervous system
        Amyotrophic lateral sclerosis
        Brachial amyotrophic diplegia
        Cerebral palsy
        Dementia
        Dentatorubral-pallidoluysian atrophy
        Extrapyramidal disease
        Frontotemporal dementia with motor neuron disease
        Huntington disease
        Pick disease
        Pigmentary pallidal degeneration
        Progressive supranuclear palsy
        Spinocerebellar atrophy
        Striatonigral degeneration
        Infantile neuroaxonal dystrophy
        Meningitis
        Aseptic meningitis
        Bacterial meningitis
        Chronic lymphocytic meningitis
        Eosinophilic meningitis
        Fungal meningitis
        Lymphocytic choriomeningitis
        Viral meningitis
        Neurodevelopmental disorder
        Attention Deficit and Disruptive Behavior Disorders
        Brain Development Abnormality
        Child Behavior Disorders
        Child Development Disorders, Pervasive
        Childhood-onset schizophrenia
        communication disorder
        Developmental disorder
        Fetal Neurodevelopmental Disorder
        Gabriele de Vries syndrome
        Intellectual disability
        Learning disability
        Motor skill disorder
        Mutism
        reactive attachment disorder
        Separation anxiety disorder
        Stereotypic movement disorder
        Tic
        Neuronitis
        Non-Neoplastic Brain Disorder
        Cerebellar degeneration
        Cerebrovascular disorder
        Corticobasal degeneration disorder
        Encephalitis
        Encephalomalacia
        Epilepsy
        Hemimegalencephaly
        Hydrocephalus
        Olivopontocerebellar atrophy
        Thalamic disorder
        Secondary Parkinson disease
        Postencephalitic Parkinson disease
        Sensory disorder
        Disorder of taste
        Tactile Disorder
        Syringomyelia
        Primary syringomyelia
        Secondary syringomyelia
        Syringomyelia and Hydromyelia
        Non-Neoplastic Optic Nerve Disorder
        Optic neuropathy
        Nonarteritic anterior ischemic optic neuropathy
        Optic neuritis
        Non-Neoplastic Peripheral Nervous System Disorder
        Abnormal autonomic nervous system physiology
        Abnormal sudomotor regulation
        Autonomic bladder dysfunction
        Horner syndrome
        Multiple system atrophy
        Neurocirculatory asthenia
        Orthostatic hypotension
        Orthostatic tachycardia
        Pure autonomic failure
        Reduced sympathoneural responses to the cold pressor test
        Brachial plexus neuritis
        Neuritis
        Polyneuritis
        Neuroma
        Appendix Neuroma
        Multiple mucosal neuromas
        Schwannoma
        Traumatic neuroma
        Radiculitis
        Non-Neoplastic Trigeminal Nerve Disorder

Professional guidelines

PubMed

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J Clin Invest 2023 Jun 15;133(12) doi: 10.1172/JCI168035. PMID: 37104042 Free PMC Article

Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment.

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Recent clinical studies

Etiology

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Diagnosis

In and around the pineal gland: a neuroimaging review.

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Intramedullary tumours and tumour mimics.

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Multiple ring-enhancing lesions of the brain.

Garg RK, Sinha MK
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Non-neoplastic pineal cysts.

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Therapy

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Prognosis

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Clinical prediction guides

Radiotherapy-Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth.

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Multiparametric Imaging Analysis: Magnetic Resonance Spectroscopy.

Rapalino O, Ratai EM
Magn Reson Imaging Clin N Am 2016 Nov;24(4):671-686. Epub 2016 Sep 13 doi: 10.1016/j.mric.2016.06.001. PMID: 27742109

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Non-neoplastic pineal cysts.

Fetell MR, Bruce JN, Burke AM, Cross DT, Torres RA, Powers JM, Stein BM
Neurology 1991 Jul;41(7):1034-40. doi: 10.1212/wnl.41.7.1034. PMID: 2067630

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Recent systematic reviews

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Xanthogranuloma of the sellar region: a systematic review.

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