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Esophageal web

MedGen UID:
473003
Concept ID:
C0267080
Anatomical Abnormality; Finding
Synonym: Esophageal webbing
SNOMED CT: Esophageal web (19216006); Esophageal body web (22395006); Webbed esophagus (22395006)
 
HPO: HP:0100594

Definition

Thin (2-3mm) membranes of normal esophageal tissue consisting of mucosa and submucosa that can be congenital or acquired. Congenital webs commonly appear in the middle and inferior third of the esophagus, and they are more likely to be circumferential with a central or eccentric orifice. Acquired webs are much more common than congenital webs and typically appear in the cervical area (postcricoid). Clinical symptoms of this condition are selective (solid more than liquids) dysphagia, thoracic pain, nasopharyngeal reflux, aspiration, perforation and food impaction (the last two are very rare). [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Ravich WJ
Curr Gastroenterol Rep 2017 Aug 24;19(10):50. doi: 10.1007/s11894-017-0591-8. PMID: 28840483
Fan Y, Song HY, Kim JH, Park JH, Ponnuswamy I, Jung HY, Kim YH
AJR Am J Roentgenol 2011 Dec;197(6):1481-6. doi: 10.2214/AJR.11.6591. PMID: 22109306
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME
Biol Blood Marrow Transplant 2005 Dec;11(12):945-56. doi: 10.1016/j.bbmt.2005.09.004. PMID: 16338616

Recent clinical studies

Etiology

Boybeyi-Turer O, Iyigun I, Cagan M, Celik HT, Ozyuncu O, Soyer T
Congenit Anom (Kyoto) 2021 Nov;61(6):208-211. Epub 2021 Jul 27 doi: 10.1111/cga.12441. PMID: 34273127
Bognár L, Vereczkei A, Papp A, Jancsó G, Horváth ÖP
Dig Dis Sci 2018 Oct;63(10):2529-2535. Epub 2018 Jul 11 doi: 10.1007/s10620-018-5184-3. PMID: 29995182
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME
Biol Blood Marrow Transplant 2005 Dec;11(12):945-56. doi: 10.1016/j.bbmt.2005.09.004. PMID: 16338616
Lao J, Bostwick HE, Berezin S, Halata MS, Newman LJ, Medow MS
Pediatr Emerg Care 2003 Dec;19(6):402-7. doi: 10.1097/01.pec.0000101581.65509.17. PMID: 14676489

Diagnosis

Boybeyi-Turer O, Iyigun I, Cagan M, Celik HT, Ozyuncu O, Soyer T
Congenit Anom (Kyoto) 2021 Nov;61(6):208-211. Epub 2021 Jul 27 doi: 10.1111/cga.12441. PMID: 34273127
Goel A, Lakshmi CP, Bakshi SS, Soni N, Koshy S
Dis Esophagus 2016 Oct;29(7):837-841. Epub 2015 Jul 30 doi: 10.1111/dote.12393. PMID: 26227908
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME
Biol Blood Marrow Transplant 2005 Dec;11(12):945-56. doi: 10.1016/j.bbmt.2005.09.004. PMID: 16338616
Atmatzidis K, Papaziogas B, Pavlidis T, Mirelis Ch, Papaziogas T
Dis Esophagus 2003;16(2):154-7. doi: 10.1046/j.1442-2050.2003.00316.x. PMID: 12823219

Therapy

Ravich WJ
Curr Gastroenterol Rep 2017 Aug 24;19(10):50. doi: 10.1007/s11894-017-0591-8. PMID: 28840483
Sinha SK, Nain CK, Udawat HP, Prasad KK, Das R, Nagi B, Singh K
J Gastroenterol Hepatol 2008 Jul;23(7 Pt 1):1149-52. Epub 2008 Jun 28 doi: 10.1111/j.1440-1746.2008.05452.x. PMID: 18554241
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME
Biol Blood Marrow Transplant 2005 Dec;11(12):945-56. doi: 10.1016/j.bbmt.2005.09.004. PMID: 16338616
Atmatzidis K, Papaziogas B, Pavlidis T, Mirelis Ch, Papaziogas T
Dis Esophagus 2003;16(2):154-7. doi: 10.1046/j.1442-2050.2003.00316.x. PMID: 12823219

Prognosis

Patil M, Malipatel R, Devarbhavi H
J Gastroenterol Hepatol 2021 Jan;36(1):181-185. Epub 2020 Jun 29 doi: 10.1111/jgh.15139. PMID: 32525241
Fan Y, Song HY, Kim JH, Park JH, Ponnuswamy I, Jung HY, Kim YH
AJR Am J Roentgenol 2011 Dec;197(6):1481-6. doi: 10.2214/AJR.11.6591. PMID: 22109306
Chao HC, Chen SY, Kong MS
J Pediatr Surg 2008 Jan;43(1):e13-5. doi: 10.1016/j.jpedsurg.2007.08.059. PMID: 18206438
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Lao J, Bostwick HE, Berezin S, Halata MS, Newman LJ, Medow MS
Pediatr Emerg Care 2003 Dec;19(6):402-7. doi: 10.1097/01.pec.0000101581.65509.17. PMID: 14676489

Clinical prediction guides

Belafsky PC, Plowman EK, Mehdizadeh O, Cates D, Domer A, Yen K
Ann Otol Rhinol Laryngol 2013 Apr;122(4):217-21. doi: 10.1177/000348941312200401. PMID: 23697317
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, Martin P, Chien J, Przepiorka D, Couriel D, Cowen EW, Dinndorf P, Farrell A, Hartzman R, Henslee-Downey J, Jacobsohn D, McDonald G, Mittleman B, Rizzo JD, Robinson M, Schubert M, Schultz K, Shulman H, Turner M, Vogelsang G, Flowers ME
Biol Blood Marrow Transplant 2005 Dec;11(12):945-56. doi: 10.1016/j.bbmt.2005.09.004. PMID: 16338616
Mattioli S, Raspadori A, Di Simone MP, Brusori S, Vernacchia R, Gozzetti G
Surg Endosc 1992 Sep-Oct;6(5):249-51. doi: 10.1007/BF02498814. PMID: 1465734
Tucker LE
Mo Med 1992 Sep;89(9):668-70. PMID: 1406561

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