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Ampulla of Vater Undifferentiated Carcinoma with Osteoclast-Like Giant Cells

MedGen UID:
474096
•Concept ID:
C3272463
•
Neoplastic Process

Definition

A rare variant of undifferentiated carcinoma that arises from the ampulla of Vater. It is characterized by the presence of non-neoplastic, histiocytic, osteoclast-like multinucleated giant cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of Vater Undifferentiated Carcinoma with Osteoclast-Like Giant Cells

Recent clinical studies

Diagnosis

Surgically resected undifferentiated carcinoma with osteoclast-like giant cells of the periampullary region involving the orifice of the papilla of Vater: Report of a case.
Matsuzawa G, Shirabe K, Gion T, Tsujita E, Ooya M, Kajiyama K, Nagaie T
Surg Today 2010 Apr;40(4):376-9. Epub 2010 Mar 26 doi: 10.1007/s00595-009-4078-6. PMID: 20339995
Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region.
Molberg KH, Heffess C, Delgado R, Albores-Saavedra J
Cancer 1998 Apr 1;82(7):1279-87. doi: 10.1002/(sici)1097-0142(19980401)82:7<1279::aid-cncr10>3.0.co;2-3. PMID: 9529019

Prognosis

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region.
Molberg KH, Heffess C, Delgado R, Albores-Saavedra J
Cancer 1998 Apr 1;82(7):1279-87. doi: 10.1002/(sici)1097-0142(19980401)82:7<1279::aid-cncr10>3.0.co;2-3. PMID: 9529019

Clinical prediction guides

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region.
Molberg KH, Heffess C, Delgado R, Albores-Saavedra J
Cancer 1998 Apr 1;82(7):1279-87. doi: 10.1002/(sici)1097-0142(19980401)82:7<1279::aid-cncr10>3.0.co;2-3. PMID: 9529019

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