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Bile Duct Intraductal Papillary Neoplasm, Low Grade

MedGen UID:
474682
•Concept ID:
C3273049
•
Neoplastic Process
Synonyms: Bile Duct Intraductal Papillary Neoplasm with Low Grade Intraepithelial Neoplasia; Bile Duct Intraductal Papillary Neoplasm, Low-Grade; Bile Duct IPN with Low Grade Intraepithelial Neoplasia; Bile Duct Papillary Neoplasm with Low Grade Intraepithelial Neoplasia; Intraductal Papillary Neoplasm with Low Grade Intraepithelial Neoplasia; Intraductal papillary neoplasm with low-grade intraepithelial neoplasia
SNOMED CT: Intraductal papillary neoplasm with low-grade intraepithelial neoplasia (734091005)

Definition

An intraductal papillary neoplasm that arises from the epithelium of the intrahepatic or extrahepatic bile ducts. It is characterized by the presence of mild epithelial atypia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBile Duct Intraductal Papillary Neoplasm, Low Grade

Recent clinical studies

Etiology

A brief review of the WHO reporting system for pancreaticobiliary cytopathology.
Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
The World Health Organization Reporting System for Pancreaticobiliary Cytopathology.
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Preneoplastic lesions in the liver: Molecular insights and relevance for clinical practice.
Desjonqueres E, Campani C, Marra F, Zucman-Rossi J, Nault JC
Liver Int 2022 Mar;42(3):492-506. Epub 2022 Jan 17 doi: 10.1111/liv.15152. PMID: 34982503
Prognostic Factors for Surgically Resected Intraductal Papillary Neoplasm of the Bile Duct: A Retrospective Cohort Study.
Uemura S, Higuchi R, Yazawa T, Izumo W, Matsunaga Y, Shiihara M, Ota T, Furukawa T, Yamamoto M
Ann Surg Oncol 2021 Feb;28(2):826-834. Epub 2020 Jul 10 doi: 10.1245/s10434-020-08835-6. PMID: 32651697
Intraductal papillary neoplasm of the bile duct (IPNB): CT and MRI appearance with radiology-pathology correlation.
Aslam A, Wasnik AP, Shi J, Sahai V, Mendiratta-Lala M
Clin Imaging 2020 Oct;66:10-17. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.036. PMID: 32438236Free PMC Article

Diagnosis

A brief review of the WHO reporting system for pancreaticobiliary cytopathology.
Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
The World Health Organization Reporting System for Pancreaticobiliary Cytopathology.
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct.
Sakai Y, Ohtsuka M, Sugiyama H, Mikata R, Yasui S, Ohno I, Iino Y, Kato J, Tsuyuguchi T, Kato N
World J Gastroenterol 2021 Apr 21;27(15):1569-1577. doi: 10.3748/wjg.v27.i15.1569. PMID: 33958844Free PMC Article
Intraductal papillary neoplasm of bile duct: all rare in one.
Chaturvedi A, Pol MM, Jangra K, Singh P
BMJ Case Rep 2020 Nov 9;13(11) doi: 10.1136/bcr-2020-237001. PMID: 33168532Free PMC Article
Intraductal papillary neoplasm of the bile duct (IPNB): CT and MRI appearance with radiology-pathology correlation.
Aslam A, Wasnik AP, Shi J, Sahai V, Mendiratta-Lala M
Clin Imaging 2020 Oct;66:10-17. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.036. PMID: 32438236Free PMC Article

Prognosis

A brief review of the WHO reporting system for pancreaticobiliary cytopathology.
Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
The World Health Organization Reporting System for Pancreaticobiliary Cytopathology.
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct.
Sakai Y, Ohtsuka M, Sugiyama H, Mikata R, Yasui S, Ohno I, Iino Y, Kato J, Tsuyuguchi T, Kato N
World J Gastroenterol 2021 Apr 21;27(15):1569-1577. doi: 10.3748/wjg.v27.i15.1569. PMID: 33958844Free PMC Article
Low-Grade Dysplastic Intracholecystic Papillary Neoplasia: A Case Report.
Logrado A, Constantino J, Daniel C, Pereira J, Carvalho MT, Casimiro C
Am J Case Rep 2021 Mar 3;22:e929788. doi: 10.12659/AJCR.929788. PMID: 33654049Free PMC Article
Prognostic Factors for Surgically Resected Intraductal Papillary Neoplasm of the Bile Duct: A Retrospective Cohort Study.
Uemura S, Higuchi R, Yazawa T, Izumo W, Matsunaga Y, Shiihara M, Ota T, Furukawa T, Yamamoto M
Ann Surg Oncol 2021 Feb;28(2):826-834. Epub 2020 Jul 10 doi: 10.1245/s10434-020-08835-6. PMID: 32651697

Clinical prediction guides

Development of intraductal papillary neoplasm of the bile duct in patients with occupational cholangiocarcinoma.
Kubo S, Tanaka S, Kinoshita M, Shinkawa H, Ishizawa T, Sato Y
Virchows Arch 2023 Apr;482(4):745-753. Epub 2023 Jan 30 doi: 10.1007/s00428-023-03499-5. PMID: 36715769
Intraductal papillary mucinous neoplasm of the biliary tract with cardiac metastasis: A case report.
Lee JH, Kim HS, Park JH, Park JS
Medicine (Baltimore) 2021 Jan 22;100(3):e24310. doi: 10.1097/MD.0000000000024310. PMID: 33546060Free PMC Article
Reappraisal of pathological features of intraductal papillary neoplasm of bile duct with respect to the type 1 and 2 subclassifications.
Nakanuma Y, Uesaka K, Okamura Y, Terada T, Fukumura Y, Kakuda Y, Sugino T, Sato Y, Taek JK, Park YN
Hum Pathol 2021 May;111:21-35. Epub 2021 Jan 27 doi: 10.1016/j.humpath.2021.01.002. PMID: 33508254
Intraductal papillary neoplasm of the bile duct (IPNB): CT and MRI appearance with radiology-pathology correlation.
Aslam A, Wasnik AP, Shi J, Sahai V, Mendiratta-Lala M
Clin Imaging 2020 Oct;66:10-17. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.036. PMID: 32438236Free PMC Article
Upregulation of follistatin and low apoptotic activity in intraductal oncocytic papillary neoplasm of the pancreatobiliary system.
Nakahodo J, Fukumura Y, Saito T, Hirabayashi K, Doi R, Hayashi T, Yao T
Sci Rep 2020 May 18;10(1):8179. doi: 10.1038/s41598-020-64920-6. PMID: 32424306Free PMC Article

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