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Peripheral vitreoretinal degeneration

MedGen UID:
481979
•Concept ID:
C3280349
•
Finding
HPO: HP:0200071

Definition

A type of vitreoretinal degeneration with manifestations that are concentrated at the periphery of the retina. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral vitreoretinal degeneration

Conditions with this feature

Myopia, high, with cataract and vitreoretinal degeneration
MedGen UID:
481976
•Concept ID:
C3280346
•
Disease or Syndrome
See: Condition Record
Myopia, high, with cataract and vitreoretinal degeneration

Professional guidelines

PubMed

Recommendations for management of peripheral retinal degenerations.
Venkatesh R, Sharief S, Thadani A, Ratra D, Mohan S, Narayanan R, Narula R, Asad Y, Roy R, Jayadev C, Yadav NK
Indian J Ophthalmol 2022 Oct;70(10):3681-3686. doi: 10.4103/ijo.IJO_689_22. PMID: 36190072Free PMC Article

Recent clinical studies

Etiology

Bilateral macular hole in a patient with CAPN5-related neovascular inflammatory vitreoretinopathy.
Choi YJ, Woo SJ, Joo K
Doc Ophthalmol 2023 Dec;147(3):211-216. Epub 2023 Sep 5 doi: 10.1007/s10633-023-09946-7. PMID: 37668859
Visualisation of peripheral retinal degenerations and anomalies with ocular imaging.
Cheung R, Ly A, Katalinic P, Coroneo MT, Chang A, Kalloniatis M, Madigan MC, Nivison-Smith L
Semin Ophthalmol 2022 Jul 4;37(5):554-582. Epub 2022 Mar 7 doi: 10.1080/08820538.2022.2039222. PMID: 35254953
Coexistence of Peripheral Retinal Diseases with Macular Hole.
Yaşar E, Erol N, Bilgeç MD, Çakmak Aİ
Turk J Ophthalmol 2019 Sep 3;49(4):209-212. doi: 10.4274/tjo.galenos.2019.06706. PMID: 31486608Free PMC Article
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.
Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ, Hubschman JP, Davis JL, Heilwell G, Spirn M, Maguire J, Gay R, Bateman J, Ostrick RM, Morris D, Vincent M, Anglade E, Del Priore LV, Lanza R
Lancet 2015 Feb 7;385(9967):509-16. Epub 2014 Oct 15 doi: 10.1016/S0140-6736(14)61376-3. PMID: 25458728
Lattice degeneration of the retina and retinal detachment.
Semes LP
Optom Clin 1992;2(3):71-91. PMID: 1463916

Diagnosis

Navigated single-capture 3D and cross-sectional wide-field OCT of the mid and peripheral retina and vitreoretinal interface.
Stanga PE, Pastor-Idoate S, Reinstein U, Vatas P, Patel U, Dubovy S, Reinstein DZ, Zahavi O
Eur J Ophthalmol 2022 May;32(3):1642-1651. Epub 2021 Jul 3 doi: 10.1177/11206721211026100. PMID: 34218694
Coexistence of Peripheral Retinal Diseases with Macular Hole.
Yaşar E, Erol N, Bilgeç MD, Çakmak Aİ
Turk J Ophthalmol 2019 Sep 3;49(4):209-212. doi: 10.4274/tjo.galenos.2019.06706. PMID: 31486608Free PMC Article
Congenital X-Linked Retinoschisis: An Updated Clinical Review.
Rao P, Dedania VS, Drenser KA
Asia Pac J Ophthalmol (Phila) 2018 May-Jun;7(3):169-175. Epub 2018 Apr 9 doi: 10.22608/APO.201803. PMID: 29633586
Presbyopia-correcting intraocular lenses and corneal refractive procedures: a review for retinal surgeons.
Ahmad BU, Shah GK, Hardten DR
Retina 2014 Jun;34(6):1046-54. doi: 10.1097/IAE.0000000000000237. PMID: 24849701
Goldmann-Favre vitreoretinal degeneration.
Batioğlu F
Eur J Ophthalmol 2003 Apr;13(3):307-10. doi: 10.1177/112067210301300311. PMID: 12747653

Therapy

Macular Hole-Related Retinal Detachment in Children with Knobloch Syndrome.
Alsulaiman SM, Al-Abdullah AA, Alakeely A, Aldhibi H, Engelbrecht L, Ghazi NG, Mura M
Ophthalmol Retina 2020 May;4(5):498-503. Epub 2019 Dec 12 doi: 10.1016/j.oret.2019.12.004. PMID: 32111543
Evaluation of hyaloid-retinal relationship during triamcinolone-assisted vitrectomy for primary rhegmatogenous retinal detachment.
Sundar D, Takkar B, Venkatesh P, Chawla R, Temkar S, Azad SV, Vohra R
Eur J Ophthalmol 2018 Sep;28(5):607-613. Epub 2018 Mar 23 doi: 10.1177/1120672118754301. PMID: 29569478
Rhegmatogenous retinal detachment following intravitreal ocriplasmin.
Madi HA, Haynes RJ, Depla D, de la Cour MD, Lesnik-Oberstein S, Muqit MM, Patton N, Price N, Steel DH
Graefes Arch Clin Exp Ophthalmol 2016 Dec;254(12):2333-2338. Epub 2016 Jun 8 doi: 10.1007/s00417-016-3398-7. PMID: 27278373Free PMC Article
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.
Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ, Hubschman JP, Davis JL, Heilwell G, Spirn M, Maguire J, Gay R, Bateman J, Ostrick RM, Morris D, Vincent M, Anglade E, Del Priore LV, Lanza R
Lancet 2015 Feb 7;385(9967):509-16. Epub 2014 Oct 15 doi: 10.1016/S0140-6736(14)61376-3. PMID: 25458728
Lattice degeneration of the retina and retinal detachment.
Semes LP
Optom Clin 1992;2(3):71-91. PMID: 1463916

Prognosis

Evaluation of hyaloid-retinal relationship during triamcinolone-assisted vitrectomy for primary rhegmatogenous retinal detachment.
Sundar D, Takkar B, Venkatesh P, Chawla R, Temkar S, Azad SV, Vohra R
Eur J Ophthalmol 2018 Sep;28(5):607-613. Epub 2018 Mar 23 doi: 10.1177/1120672118754301. PMID: 29569478
Rhegmatogenous retinal detachment following intravitreal ocriplasmin.
Madi HA, Haynes RJ, Depla D, de la Cour MD, Lesnik-Oberstein S, Muqit MM, Patton N, Price N, Steel DH
Graefes Arch Clin Exp Ophthalmol 2016 Dec;254(12):2333-2338. Epub 2016 Jun 8 doi: 10.1007/s00417-016-3398-7. PMID: 27278373Free PMC Article
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.
Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ, Hubschman JP, Davis JL, Heilwell G, Spirn M, Maguire J, Gay R, Bateman J, Ostrick RM, Morris D, Vincent M, Anglade E, Del Priore LV, Lanza R
Lancet 2015 Feb 7;385(9967):509-16. Epub 2014 Oct 15 doi: 10.1016/S0140-6736(14)61376-3. PMID: 25458728
Clinical features of the congenital vitreoretinopathies.
Edwards AO
Eye (Lond) 2008 Oct;22(10):1233-42. Epub 2008 Feb 29 doi: 10.1038/eye.2008.38. PMID: 18309337
Lattice degeneration of the retina and retinal detachment.
Semes LP
Optom Clin 1992;2(3):71-91. PMID: 1463916

Clinical prediction guides

Bilateral macular hole in a patient with CAPN5-related neovascular inflammatory vitreoretinopathy.
Choi YJ, Woo SJ, Joo K
Doc Ophthalmol 2023 Dec;147(3):211-216. Epub 2023 Sep 5 doi: 10.1007/s10633-023-09946-7. PMID: 37668859
Knobloch syndrome - a rare collagenopathy, revealing peripheral avascular retina.
Maitra P, Shah PK, S P, Das A, V N
Ophthalmic Genet 2023 Dec;44(6):618-622. Epub 2023 Mar 30 doi: 10.1080/13816810.2023.2188226. PMID: 36994995
Navigated single-capture 3D and cross-sectional wide-field OCT of the mid and peripheral retina and vitreoretinal interface.
Stanga PE, Pastor-Idoate S, Reinstein U, Vatas P, Patel U, Dubovy S, Reinstein DZ, Zahavi O
Eur J Ophthalmol 2022 May;32(3):1642-1651. Epub 2021 Jul 3 doi: 10.1177/11206721211026100. PMID: 34218694
Coexistence of Peripheral Retinal Diseases with Macular Hole.
Yaşar E, Erol N, Bilgeç MD, Çakmak Aİ
Turk J Ophthalmol 2019 Sep 3;49(4):209-212. doi: 10.4274/tjo.galenos.2019.06706. PMID: 31486608Free PMC Article
WAGNER syndrome: anatomic, functional and genetic characterization of a Portuguese family.
Araújo JR, Tavares-Ferreira J, Estrela-Silva S, Rocha P, Brandão E, Faria PA, Falcão-Reis F, Rocha-Sousa A
Graefes Arch Clin Exp Ophthalmol 2018 Jan;256(1):163-171. Epub 2017 Oct 25 doi: 10.1007/s00417-017-3800-0. PMID: 29071374

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