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Abnormal posterior eye segment morphology

MedGen UID:
870893
•Concept ID:
C4025354
•
Anatomical Abnormality
Synonyms: Abnormal morphology of the posterior segment of the globe; Abnormality of the posterior segment of the eye; Abnormality of the posterior segment of the eyeball; Abnormality of the posterior segment of the globe
 
HPO: HP:0004329

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal posterior eye segment morphology

Professional guidelines

PubMed

Accidentally diagnosed ocular abnormalities identified during close screening for retinopathy of prematurity.
Ozturk T, Durmaz Engin C, Karatas Yigitaslan E, Yaman A, Berk T
Eur J Ophthalmol 2022 Nov;32(6):3267-3273. Epub 2022 Mar 9 doi: 10.1177/11206721221086252. PMID: 35261269
Current concepts in the treatment of vitreous block, also known as aqueous misdirection.
Kaplowitz K, Yung E, Flynn R, Tsai JC
Surv Ophthalmol 2015 May-Jun;60(3):229-41. Epub 2014 Dec 27 doi: 10.1016/j.survophthal.2014.12.004. PMID: 25639795
The differential diagnosis of leukokoria.
Cheng KP, Hiles DA, Biglan AW
Pediatr Ann 1990 Jun;19(6):376-83, 386. doi: 10.3928/0090-4481-19900601-07. PMID: 2200999

Recent clinical studies

Etiology

Axenfeld-Rieger syndrome: a novel histopathologic finding associated with corneal abnormalities.
Yu T, Dai Z, Peng R, Xiao G, Zhang P, Ma S, Hong J
BMC Ophthalmol 2022 Dec 28;22(1):514. doi: 10.1186/s12886-022-02754-8. PMID: 36577962Free PMC Article
Ocular Phenotype of Peters-Plus Syndrome.
Shah PR, Chauhan B, Chu CT, Kofler J, Nischal KK
Cornea 2022 Feb 1;41(2):219-223. doi: 10.1097/ICO.0000000000002889. PMID: 34629439
Vascular abnormalities in uveitis.
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
Optical Coherence Tomography Angiography in Amblyopia.
Kaur S, Singh SR, Katoch D, Dogra MR, Sukhija J
Ophthalmic Surg Lasers Imaging Retina 2019 Nov 1;50(11):e294-e299. doi: 10.3928/23258160-20191031-17. PMID: 31755981
Genetics in pediatric ophthalmology.
Bateman JB
Pediatr Clin North Am 1983 Dec;30(6):1015-31. doi: 10.1016/s0031-3955(16)34499-6. PMID: 6359041

Diagnosis

Alzheimer's Disease Seen through the Eye: Ocular Alterations and Neurodegeneration.
Romaus-Sanjurjo D, Regueiro U, López-López M, Vázquez-Vázquez L, Ouro A, Lema I, Sobrino T
Int J Mol Sci 2022 Feb 24;23(5) doi: 10.3390/ijms23052486. PMID: 35269629Free PMC Article
Ocular Phenotype of Peters-Plus Syndrome.
Shah PR, Chauhan B, Chu CT, Kofler J, Nischal KK
Cornea 2022 Feb 1;41(2):219-223. doi: 10.1097/ICO.0000000000002889. PMID: 34629439
Vascular abnormalities in uveitis.
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
Simple microphthalmos.
Weiss AH, Kousseff BG, Ross EA, Longbottom J
Arch Ophthalmol 1989 Nov;107(11):1625-30. doi: 10.1001/archopht.1989.01070020703032. PMID: 2818284
Complex microphthalmos.
Weiss AH, Kousseff BG, Ross EA, Longbottom J
Arch Ophthalmol 1989 Nov;107(11):1619-24. doi: 10.1001/archopht.1989.01070020697031. PMID: 2818283

Therapy

Glaucoma With Crouzon Syndrome.
Alshamrani AA, Al-Shahwan S
J Glaucoma 2018 Jun;27(6):e110-e112. doi: 10.1097/IJG.0000000000000946. PMID: 29557836
From the analysis of pharmacologic vitreolysis to the comprehension of ocriplasmin safety.
Morescalchi F, Gambicorti E, Duse S, Costagliola C, Semeraro F
Expert Opin Drug Saf 2016 Sep;15(9):1267-78. Epub 2016 Jul 20 doi: 10.1080/14740338.2016.1208169. PMID: 27388220
Non-invasive anterior segment and posterior segment optical coherence tomography and phenotypic characterization of aniridia.
Gregory-Evans K, Cheong-Leen R, George SM, Xie J, Moosajee M, Colapinto P, Gregory-Evans CY
Can J Ophthalmol 2011 Aug;46(4):337-44. Epub 2011 Jul 7 doi: 10.1016/j.jcjo.2011.06.011. PMID: 21816254
Talc retinopathy.
Tse DT, Ober RR
Am J Ophthalmol 1980 Nov;90(5):624-40. doi: 10.1016/s0002-9394(14)75129-3. PMID: 6160767
The vitreous.
Tolentino FI
Arch Ophthalmol 1974 Oct;92(4):350-8. doi: 10.1001/archopht.1974.01010010360022. PMID: 4607273

Prognosis

Alzheimer's Disease Seen through the Eye: Ocular Alterations and Neurodegeneration.
Romaus-Sanjurjo D, Regueiro U, López-López M, Vázquez-Vázquez L, Ouro A, Lema I, Sobrino T
Int J Mol Sci 2022 Feb 24;23(5) doi: 10.3390/ijms23052486. PMID: 35269629Free PMC Article
Pigment dispersion syndrome and pigmentary glaucoma: a review and update.
Scuderi G, Contestabile MT, Scuderi L, Librando A, Fenicia V, Rahimi S
Int Ophthalmol 2019 Jul;39(7):1651-1662. Epub 2018 May 2 doi: 10.1007/s10792-018-0938-7. PMID: 29721842
Interocular Comparison of Anterior and Posterior Segment Findings and Laterality in Hyperopic Anisometropia.
Cankurtaran V, Tekin K, Şimşek M, Elgin U, Yilmazbaş P
Eye Contact Lens 2018 Jan;44(1):29-34. doi: 10.1097/ICL.0000000000000296. PMID: 27541970
The Wagner-Stickler syndrome complex.
Godel V, Nemet P, Lazar M
Doc Ophthalmol 1981 Dec 16;52(2):179-88. doi: 10.1007/BF01675204. PMID: 7035111
Birdshot retinochoroidopathy.
Kaplan HJ, Aaberg TM
Am J Ophthalmol 1980 Dec;90(6):773-82. doi: 10.1016/s0002-9394(14)75192-x. PMID: 7446664

Clinical prediction guides

Alzheimer's Disease Seen through the Eye: Ocular Alterations and Neurodegeneration.
Romaus-Sanjurjo D, Regueiro U, López-López M, Vázquez-Vázquez L, Ouro A, Lema I, Sobrino T
Int J Mol Sci 2022 Feb 24;23(5) doi: 10.3390/ijms23052486. PMID: 35269629Free PMC Article
Ocular Phenotype of Peters-Plus Syndrome.
Shah PR, Chauhan B, Chu CT, Kofler J, Nischal KK
Cornea 2022 Feb 1;41(2):219-223. doi: 10.1097/ICO.0000000000002889. PMID: 34629439
Glaucoma With Crouzon Syndrome.
Alshamrani AA, Al-Shahwan S
J Glaucoma 2018 Jun;27(6):e110-e112. doi: 10.1097/IJG.0000000000000946. PMID: 29557836
Clinical and molecular aspects of aniridia.
Kokotas H, Petersen MB
Clin Genet 2010 May;77(5):409-20. Epub 2010 Jan 6 doi: 10.1111/j.1399-0004.2010.01372.x. PMID: 20132240
Ocular complications.
Engerman R, Finkelstein D, Aguirre G, Diddie KR, Fox RR, Frank RN, Varma SD
Diabetes 1982;31(Suppl 1 Pt 2):82-8. doi: 10.2337/diab.31.1.s82. PMID: 6819171

Recent systematic reviews

Global prevalence of asteroid hyalosis and projection of its future burden: a systematic review and meta-analysis.
Møller-Lorentzen TB, Eckmann-Hansen C, Faber C, Larsen M, Subhi Y
Acta Ophthalmol 2020 Dec;98(8):755-762. Epub 2020 May 15 doi: 10.1111/aos.14465. PMID: 32410360
Tears and Eyewear in Forensic Investigation-A Review.
Aparna R, Shanti Iyer R
Forensic Sci Int 2020 Jan;306:110055. Epub 2019 Nov 15 doi: 10.1016/j.forsciint.2019.110055. PMID: 31785512
Ocular involvement in systemic sclerosis: A systematic literature review, it's not all scleroderma that meets the eye.
Kreps EO, Carton C, Cutolo M, Cutolo CA, Vanhaecke A, Leroy BP, Smith V
Semin Arthritis Rheum 2019 Aug;49(1):119-125. Epub 2018 Dec 28 doi: 10.1016/j.semarthrit.2018.12.007. PMID: 30660382

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